芳香伯胺的毒性、危害和安全处理,ACS Chemical Health & Safety

当前位置： X-MOL 学术 › ACS Chem. Health Saf. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

芳香伯胺的毒性、危害和安全处理
ACS Chemical Health & Safety ( IF 2.9 ) Pub Date : 2023-11-09 , DOI: 10.1021/acs.chas.3c00073
Saba A. Gheni ₁ , Mudheher M. Ali ₁ , Goh C. Ta ₂ , Hannah J. Harbin ₃ , Saad A. Awad ₄

Affiliation

芳香胺 (AA) 是一类重要的有机化合物，在染料生产、橡胶制造和药物合成等多种行业中都有应用。尽管有各种应用，但它们严重危害人类健康和环境。本文概述了一些芳香伯胺 (PAA) 的毒性、危害和安全处理，重点介绍代表性实例，如苯胺、甲苯胺、硝基苯胺、氯苯胺和萘胺。PAAs 的致癌性和致突变性是一个值得关注的问题，它会影响职业接触此类化学品的工人的健康。非职业性接触烟草烟雾和家用产品也会导致留在室内的老年患者出现健康问题。这些污染物造成的水和土壤污染会对水生生物和地下水质量产生不利影响。因此，必须遵循适当的处理和处置协议，以尽量减少其对人类健康和环境的影响。此外，本综述还以具体示例讨论了欧盟 (EU) 和日本对苯胺危害分类之间的差异。本次审查中提供的信息强调了了解与 PAA 相关的毒性、危害和安全处理实践的重要性，以确保负责任地使用它们并减轻潜在风险。

"点击查看英文标题和摘要"

Toxicity, Hazards, and Safe Handling of Primary Aromatic Amines

Aromatic amines (AAs) are an important class of organic compounds that find their application in various industries, such as dye production, rubber manufacturing, and pharmaceutical synthesis. Despite the various applications, they significantly harm human health and the environment. This article provides an overview of the toxicity, hazards, and safe handling of some primary aromatic amines (PAAs), focusing on representative examples, such as aniline, toluidine, nitroaniline, chloroaniline, and naphthylamine. The carcinogenicity and mutagenicity of PAAs are a matter of concern that impacts the health of workers who are occupationally exposed to such chemicals. Nonoccupational exposure to tobacco smoke and household products also causes health issues in elderly patients who remain indoors. Water and soil contamination by these pollutants adversely affects aquatic organisms and groundwater quality. Thus, proper handling and disposal protocols must be followed to minimize their impact on human health and the environment. Additionally, this review discusses the discrepancies between the European Union (EU) and Japan’s hazard categorization for aniline as a specific example. The information presented in this review emphasizes the importance of understanding toxicity, hazards, and safe handling practices associated with PAAs to ensure their responsible use and mitigate potential risks.

更新日期：2023-11-09

点击分享查看原文

点击收藏

阅读更多本刊新发论文