A novel quench molecularly imprinted electrochemiluminescence sensor (MIECLS) based on a covalent organic framework composite (COF-300-Au) with enhanced electrochemiluminescence (ECL) signal from CsPbBr₃ quantum dots and cross-linked 3-thiopheneacetic acid functionalized AuNPs (3-TAA@AuNPs) was developed for the detection of the environmental pollutant benzo(a)pyrene (BaP). A composite material constructed of COF-300-Au with a large specific surface area served as the sensor's support substrate, providing more CsPbBr₃ and imprint recognition sites. Electropolymerization was then employed to form an AuNPs three-dimensional imprinting layer with polythiophene cross-linked using BaP as a template and 3-TAA@AuNPs as a functional monomer. A specific cross-linked imprinting recognition effect was recorded on BaP along with the quenching effect of quinones. The density functional theory (DFT) evaluation of the binding mechanism between 3-TAA@AuNPs and BaP revealed powerful MIECLS toward the detection of BaP at concentrations ranging from 10⁻¹⁴ to 10⁻⁵M, with a detection limit of as low as 4.1×10⁻¹⁵ M.

一种新型淬灭分子印迹电化学发光传感器 (MIECLS)，基于共价有机骨架复合材料 (COF-300-Au)，具有来自 CsPbBr 3 量子点和交联 3-噻吩乙酸功能化 AuNP (3-TAA) 的增强电化学发光 (ECL ₎信号@AuNPs）是为检测环境污染物苯并（a）芘（BaP）而开发的。由具有大比表面积的COF-300-Au构成的复合材料作为传感器的支撑基底，提供更多的CsPbBr ₃和印记识别位点。然后以BaP为模板、3-TAA@AuNPs为功能单体，采用电聚合法形成聚噻吩交联的AuNPs三维印迹层。BaP 上记录了特定的交联印记识别效应以及醌的猝灭效应。对 3-TAA@AuNPs 和 BaP 之间结合机制的密度泛函理论 (DFT) 评估揭示了强大的 MIECLS 对浓度范围为 10 -14 至 10 -5 ^M的^BaP的检测，检测限低至 4.1 ×10 ⁻¹⁵ M。