The incorporation of weak bonds containing heteroatoms along the polymer backbone has become a popular tool to accelerate degradation. Many methods have already been reported for the synthesis of degradable heteroatom-containing polymers based mainly on conventional step-growth and chain-growth ring-opening polymerizations (ROP). In recent years, ring-opening metathesis polymerization (ROMP) has evolved as an emerging approach for the synthesis of various types of degradable polymers, from carbocyclic norbornene derivatives to heterocyclic olefin monomers. The classic/high-performance ruthenium (Ru)-based catalysts are not only highly reactive to C=C double bonds but also highly tolerant to polar functional groups. Hence, a rich library of functional groups can be incorporated into cyclic olefin monomers and then transferred to the polymer backbone. This review covers the synthesis of various degradable heteroatom-containing (co)polymers via ROMP, including poly(thio)acetals/polyketals, polyorthoesters, polyesters, polycarbonates, polyphosphoesters/polyphosphoamidates, poly(enol ether)s, poly(silyl ether)s, polydisulfides, polyketones, polyacylsilanes, polyamides, and polyureas, as well as their degradable mechanism and ability under different conditions. The review also highlights applications in tissue engineering and medicine.

沿着聚合物主链并入含有杂原子的弱键已成为加速降解的流行工具。已经报道了许多主要基于常规逐步增长和链增长开环聚合（ROP）的可降解含杂原子聚合物的合成方法。近年来，开环复分解聚合 (ROMP) 已发展成为一种合成各种类型可降解聚合物的新兴方法，从碳环降冰片烯衍生物到杂环烯烃单体。经典/高性能钌 (Ru) 基催化剂不仅对 C=C 双键具有高反应性，而且对极性官能团具有高度耐受性。因此，丰富的官能团库可以结合到环烯烃单体中，然后转移到聚合物主链上。本综述涵盖了通过 ROMP 合成各种可降解的含杂原子（共）聚合物，包括聚（硫代）缩醛/聚缩酮、聚原酸酯、聚酯、聚碳酸酯、聚磷酯/聚磷酰胺、聚（烯醇醚）、聚（硅醚） 、聚二硫化物、聚酮、聚酰基硅烷、聚酰胺和聚脲，以及它们在不同条件下的降解机理和能力。该评论还强调了组织工程和医学中的应用。聚（烯醇醚）、聚（硅醚）、聚二硫化物、聚酮、聚酰基硅烷、聚酰胺和聚脲，以及它们在不同条件下的降解机理和能力。该评论还强调了组织工程和医学中的应用。聚（烯醇醚）、聚（硅醚）、聚二硫化物、聚酮、聚酰基硅烷、聚酰胺和聚脲，以及它们在不同条件下的降解机理和能力。该评论还强调了组织工程和医学中的应用。