Materials Today Communications ( IF 3.7 ) Pub Date : 2022-10-06 , DOI: 10.1016/j.mtcomm.2022.104617 Shayan Barzegar , Mohammad Hadi Aryaie Monfared , Martin A Hubbe
Cellulose and lignin are natural, abundant, biodegradable, and environmentally friendly polymers. In addition, the presence of reactive functional groups and the ability to chemically modify cellulose and lignin provide great potential for development of products for the medical sciences and pharmaceuticals. Hydrogels in drug delivery systems have potential to give better performance of drugs. The properties of hydrogels and their constituent polymers are among the most challenging issues in this field. Research has shown that biopolymers, mainly cellulose and lignin, are excellent components for drug delivery hydrogels. These two biopolymers and their derivatives can be used as matrix hydrogels and cross-linking agents, improving mechanical properties and designing an engineered function for hydrogels, including their usage as pharmaceutical agents.
中文翻译:
纤维素和木质素作为制备药物应用水凝胶的有利候选物
纤维素和木质素是天然、丰富、可生物降解和环保的聚合物。此外,反应性官能团的存在以及对纤维素和木质素进行化学改性的能力为医学和制药产品的开发提供了巨大的潜力。药物输送系统中的水凝胶具有提高药物性能的潜力。水凝胶及其组成聚合物的性质是该领域最具挑战性的问题之一。研究表明,生物聚合物,主要是纤维素和木质素,是药物传递水凝胶的优良成分。这两种生物聚合物及其衍生物可用作基质水凝胶和交联剂,改善机械性能并设计水凝胶的工程功能,