Ten previously undescribed compounds, including two benzobicyclic ketones, one cycloheptenone oxide derivative, three guaiane-type sesquiterpenes, and four alkaloids, along with one known cycloheptenone oxide derivative, were isolated from the whole plants of Taraxacum mongolicum Hand.-Mazz. Their structures were elucidated by UV, IR, HR-ESI-MS, 1D and 2D NMR spectroscopy, ECD spectroscopy, or X-ray diffraction analysis. Notably, benzobicyclic ketones have never been isolated from nature before. The 70% EtOH–H₂O extract of T. mongolicum displayed a significant inhibitory activity (33%) against croton oil-induced mouse ear edema. The two cycloheptenone oxide derivatives exhibited anti-inflammatory activities at 10 μM and significantly reduced the nitric oxide (NO) and interleukin-6 (IL-6) levels in RAW 264.7 macrophages induced by lipopolysaccharide (LPS), with inhibitory rates of 26.4–64.4%.

从蒲公英Hand.-Mazz的全植物中分离出10种先前未描述的化合物，包括两种苯并双环酮、一种氧化环庚烯酮衍生物、三种愈创甘油醚型倍半萜和四种生物碱，以及一种已知的氧化环庚烯酮衍生物。通过紫外、红外、HR-ESI-MS、1D 和 2D NMR 光谱、ECD 光谱或 X 射线衍射分析阐明了它们的结构。值得注意的是，苯并双环酮以前从未从自然界中分离出来。蒙古木霉的 70% EtOH–H ₂ O 提取物对巴豆油诱导的小鼠耳水肿表现出显着的抑制活性（33%）。这两种环庚烯酮氧化物衍生物在 10 μM 时表现出抗炎活性，并显着降低脂多糖 (LPS) 诱导的 RAW 264.7 巨噬细胞中的一氧化氮 (NO) 和白细胞介素 6 (IL-6) 水平，抑制率为 26.4–64.4 %。