Amphipathic poly-β-peptides for intracellular protein delivery,Chemical Communications

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Amphipathic poly-β-peptides for intracellular protein delivery
Chemical Communications ( IF 4.3 ) Pub Date : 2022-03-08 , DOI: 10.1039/d2cc00453d
Qianyi Ren ₁ , Qi Chen ₂ , Lanfang Ren ₁ , Chuntao Cao ₂ , Runhui Liu ₂ , Yiyun Cheng ₁

Affiliation

A series of amphipathic poly-β-peptides are designed for intracellular protein delivery. The poly-β-peptides with higher molecular weight and hydrophobic contents exhibit higher protein loading and superior delivery efficiency. The lead material efficiently delivers proteins into cells with reserved bioactivity.

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