2,5-Dicyanofuran (DCF) is an important biomass-derived platform compound primarily used to prepare bio-based adiponitrile, which is the key precursor for the synthesis of nylon 66 and 1,6-hexanediisocyanate (HDI). In this study, one-pot, green and safe synthesis of DCF from 2,5-diformylfuran (DFF) and hydroxylamine ionic liquid salts was proposed. Eco-friendly hydroxylamine ionic liquid salts were used as the nitrogen source. Ionic liquid exhibited three-fold function of co-solvent, catalysis and phase separation. The conversion of DFF and yield of DCF reached 100% under the following optimum reaction conditions: temperature of 120 ℃ for 70 min, volume ratio of paraxylene: [HSO₃-b-Py]·HSO₄ of 2:1, and molar ratio of DFF:(NH₂OH)₂·[HSO₃-b-Py]·HSO₄ of 1:1.5. The reaction mechanism for the synthesis of DCF was proposed, and the kinetic model was established. The reaction order with respect to DFF and intermediate product 2,5-diformylfuran dioxime (DFFD) was 1.06 and 0.16, and the reaction activation energy was 64.07 kJ·mol⁻¹and 59.37 kJ·mol⁻¹ respectively. After the reaction, the ionic liquid was easy to separate, recover and recycle.

2,5-二氰基呋喃 (DCF) 是一种重要的生物质衍生平台化合物，主要用于制备生物基己二腈，是合成尼龙 66 和 1,6-己二异氰酸酯 (HDI) 的关键前体。本研究提出以2,5-二甲酰基呋喃（DFF）和羟胺离子液体盐为原料一锅法、绿色、安全地合成DCF。使用环保的羟胺离子液体盐作为氮源。离子液体表现出共溶剂、催化和相分离三重功能。在以下最佳反应条件下，DFF的转化率和DCF的收率达到100%：温度120℃，反应时间70 min，对二甲苯体积比：[HSO ₃ -b-Py]·HSO ₄为2:1，摩尔比DFF:(NH ₂ OH) ₂ ·[HSO₃ -b-Py]·HSO ₄为 1:1.5。提出了合成DCF的反应机理，建立了动力学模型。DFF和中间产物2,5-二甲酰基呋喃二肟(DFFD)的反应级数为1.06和0.16，反应活化能分别为64.07 kJ·mol ^-1和59.37 kJ·mol ^-1。反应后离子液体易于分离、回收和循环利用。