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Most recent advances on enzyme-activatable optical probes for bioimaging
Aggregate ( IF 13.9 ) Pub Date : 2021-2-12 , DOI: 10.1002/agt2.32
Ju Mei 1 , He Tian 1
Affiliation  

Enzyme-activatable optical probes are emerging as a new class of promising imaging tools for precise diagnosis of diseases at early stage with high target-to-background ratio, remarkably improved sensitivity, and dramatically enhanced specificity. This review briefly summarizes the most recent advances in this booming area, and analyzes the molecular design and working mechanism to offer insights into their biomedical applications.

中文翻译:

用于生物成像的酶激活光学探针的最新进展

酶激活光学探针正在成为一类新的有前途的成像工具,用于早期精确诊断疾病,具有高目标背景比、显着提高的灵敏度和显着增强的特异性。本综述简要总结了这一蓬勃发展领域的最新进展,并分析了分子设计和工作机制,以提供对其生物医学应用的见解。
更新日期:2021-09-22
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