World Journal of Microbiology and Biotechnology ( IF 4.0 ) Pub Date : 2021-03-29 , DOI: 10.1007/s11274-021-03041-2 Patrícia F Ávila 1 , Marcos F Silva 1 , Manoela Martins 1 , Rosana Goldbeck 1
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Abstract
Cello-oligosaccharides (COS) are linear oligosaccharides composed of β-1,4-linked glucopyranose units. They comprise a group of important new oligosaccharides of significant interest and potential applications in the pharmaceutical, food, chemical, and feed industries, currently emerging as potential prebiotic compounds. COS from lignocellulosic biomass, specifically the agro-industrial residues and by-products of the forestry industry, constitute a new attractive process that imposes the sustainable use of biomass resources. Two main strategies have been used for the production of COS: acid-based and enzyme-based cellulose hydrolysis. The latter has been considered more attractive due to the use of milder reaction conditions and less production of monomers. This review summarizes that although COS is emerging as a potential prebiotic with also other potential applications, there is a lack of information regarding the large-scale production, which could be associated with the recalcitrant nature of cellulose compared to other polysaccharides, which hinders the hydrolysis of its dense network.
Graphic abstract
中文翻译：
从木质纤维素生物质中生产纤维寡糖及其新兴的益生元应用
摘要
纤维寡糖 (COS) 是由 β-1,4-连接的吡喃葡萄糖单元组成的线性寡糖。它们包含一组在制药、食品、化学和饲料行业中具有重要意义和潜在应用的重要新寡糖，目前正作为潜在的益生元化合物出现。来自木质纤维素生物质的 COS，特别是农工业残留物和林业副产品，构成了一个新的有吸引力的过程，强制可持续利用生物质资源。两种主要策略已用于生产 COS：基于酸的和基于酶的纤维素水解。由于使用较温和的反应条件和较少的单体产量，后者被认为更具吸引力。
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