Response surface methodology was used to develop pH-sensitive gelatin-based films containing red cabbage extract and zinc oxide nanoparticles (ZnONPs). We also evaluated oxidized sucrose (OS), prepared via the periodate oxidation of sucrose, as a cross-linker to compensate for gelatin solubility. Solubility decreased in films containing higher OS levels. The minimum WVP of the cross-linked gelatin films was obtained at 12.8 % OS and high levels of ZnONPs. Antioxidant activity was reinforced by both ZnONPs and OS. Higher OS concentrations caused decreased opacity, while ZnONPs had the opposite effect. The optimum treatment included 0.043 % ZnONPs and 11.45 % OS. Together, ZnONPs and OS resulted in enhanced strength and decreased flexibility. Greater antimicrobial activity was witnessed against Staphylococcus aureus than Escherichia coli. The optimum film’s color changed from reddish-purple to blue-green between pH 3−12. In summary, we reinforced the gelatin film structure and achieved functional characteristics in a novel, intelligent, and active packaging material.

响应表面方法被用于开发包含红甘蓝提取物和氧化锌纳米颗粒（ZnONPs）的pH敏感的明胶基薄膜。我们还评估了通过蔗糖的高碘酸盐氧化制备的氧化蔗糖（OS），作为交联剂以补偿明胶的溶解度。含有较高OS含量的胶卷的溶解度降低。交联的明胶薄膜的最小WVP在OS为12.8％和高含量的ZnONP时获得。ZnONP和OS均增强了抗氧化活性。较高的OS浓度导致不透明度降低，而ZnONP具有相反的效果。最佳处理包括0.043％的ZnONP和11.45％的OS。ZnONP和OS一起导致强度提高和柔韧性下降。观察到对金黄色葡萄球菌具有更高的抗菌活性比大肠埃希菌大。最佳膜的颜色在pH值3-12之间从红紫色变为蓝绿色。总而言之，我们在一种新颖，智能且有效的包装材料中增强了明胶膜的结构并实现了功能特性。