Biosensors and Bioelectronics ( IF 10.7 ) Pub Date : 2021-01-21 , DOI: 10.1016/j.bios.2021.113011 Eric S. McLamore , Evangelyn Alocilja , Carmen Gomes , Sundaram Gunasekaran , Daniel Jenkins , Shoumen P.A. Datta , Yanbin Li , Yu (Jessie) Mao , Sam R. Nugen , José I. Reyes-De-Corcuera , Paul Takhistov , Olga Tsyusko , Jarad P. Cochran , Tzuen-Rong (Jeremy) Tzeng , Jeong-Yeol Yoon , Chenxu Yu , Anhong Zhou
We review the challenges and opportunities for biosensor research in North America aimed to accelerate translational research. We call for platform approaches based on: i) tools that can support interoperability between food, environment and agriculture, ii) open-source tools for analytics, iii) algorithms used for data and information arbitrage, and iv) use-inspired sensor design. We summarize select mobile devices and phone-based biosensors that couple analytical systems with biosensors for improving decision support. Over 100 biosensors developed by labs in North America were analyzed, including lab-based and portable devices. The results of this literature review show that nearly one quarter of the manuscripts focused on fundamental platform development or material characterization. Among the biosensors analyzed for food (post-harvest) or environmental applications, most devices were based on optical transduction (whether a lab assay or portable device). Most biosensors for agricultural applications were based on electrochemical transduction and few utilized a mobile platform. Presently, the FEAST of biosensors has produced a wealth of opportunity but faces a famine of actionable information without a platform for analytics.
中文翻译:
生物传感器的盛宴:北美的食品,环境和农业传感技术(FEAST)
我们回顾了北美旨在加速转化研究的生物传感器研究的挑战和机遇。我们要求基于以下平台方法:i)支持食品,环境与农业之间互操作性的工具,ii)用于分析的开源工具,iii)用于数据和信息套利的算法,以及iv)基于使用启发的传感器设计。我们总结了将分析系统与生物传感器结合在一起以改善决策支持的精选移动设备和基于电话的生物传感器。分析了北美实验室开发的100多种生物传感器,包括基于实验室的便携式设备。这篇文献综述的结果表明,近四分之一的手稿侧重于基础平台的开发或材料表征。在针对食品(收获后)或环境应用进行分析的生物传感器中,大多数设备都是基于光学转导的(无论是实验室分析还是便携式设备)。大多数用于农业应用的生物传感器均基于电化学转导,很少利用移动平台。当前,生物传感器的盛宴带来了很多机会,但是在没有分析平台的情况下面临着可操作信息的饥荒。