Mefentrifluconazole is the first product of a new sub-class of triazoles fungicides, i.e., the isopropanol triazoles, with the broad spectrum and high activity. In this study, the potential and biochemical activities of mefentrifluconazole against Botrytis cinerea were investigated. The frequency distribution of all EC₅₀ values of mefentrifluconazole against mycelial growth and germ tube elongation of 106 isolates formed unimodal curve, with the mean EC₅₀ values of 0.124 ± 0.025 and 0.015 ± 0.008 μg/mL, respectively. The effect of mefentrifluconazole against gray mold was determined on detached leaves of cucumber in vivo, the treatment of mefentrifluconazole at 200 μg/mL provided 100% preventative efficacy and 72.7% curative efficacy. No evident correlation was detected between the sensitivity of B. cinerea to mefentrifluconazole and that to tebuconazole, difenoconazole, myclobutanil, hexaconazole, triadimefon, flusilazole and pyrisoxazole (P > 0.05). Mefentrifluconazole treatment resulted in the increase of mycelium branch, the decrease of ergosterol content and the changes of the permeability of cell membrane. These studies evaluated the potential of mefentrifluconazole to control gray mold and helped us to understand the possible biochemical activity of mefentrifluconazole against B.cinerea.

甲芬三氟康唑是新的三唑类杀菌剂亚类的第一产品，即异丙醇三唑，具有广谱和高活性。在这项研究中，研究了潜在的和潜在的生化活性的fenfenfluconazole对灰葡萄孢。苯丙胺氟康唑的所有EC ₅₀值对106菌株的菌丝体生长和生殖管伸长的频率分布形成单峰曲线，平均EC ₅₀分别为0.124±0.025和0.015±0.008μg/ mL。在体内对黄瓜离体叶片测定了甲氰氟虫唑对灰霉病的作用，以200μg/ mL的浓度处理甲芬氟康唑可提供100％的预防效果和72.7％的疗效。灰葡萄孢菌对甲芬氟康唑的敏感性与对戊丁康唑，二苯并氟康唑，甲氯丁腈，己康唑，三唑酮，氟西拉唑和吡x唑的敏感性之间没有发现明显的相关性（P > 0.05）。甲芬氟康唑处理导致菌丝体分支增加，麦角固醇含量降低，细胞膜通透性改变。这些研究评估了甲芬氟康唑控制灰霉病的潜力，并帮助我们了解了甲芬氟康唑对B.cinerea的可能生化活性。