In patients with peripheral arterial occlusive disease (PAOD) a restricted circulation in cutaneous microvessels has been reported. In this study the velocity of erythrocytes (very) in finger nailfold capillaries - a vascular area without upstream macroangiopathy - and also in toe nailfold capillaries - a post-stenotic area -was investigated using capillary microscopy in apparently healthy subjects and patients with PAOD. Already in finger nailfold capillaries very of patients with PAOD under resting conditions was significantly lower than in capillaries of healthy subjects. This was also true for the circulation in toe capillaries. In addition, the erythrocyte velocities under resting conditions in the toe capillaries were significantly lower than in the finger capillaries. Similar results were found for the duration and the maximum velocity of postocclusive hyperemia. It is concluded that the resting blood flow in the skin microcirculation is impaired in PAOD patients, both under resting conditions and during postocclusive hyperemia in finger as well in toe nailfold capillaries.

中文翻译：

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周围动脉闭塞性疾病患者的皮肤微循环：手指和脚趾甲部毛细血管循环的比较。

据报道患有外周动脉闭塞性疾病（PAOD）的患者皮肤微血管循环受限。在这项研究中，使用毛细管显微镜在表面健康的受试者和PAOD患者中研究了手指甲皱毛细血管（无上游大血管病变的血管区域）以及脚趾甲皱毛细血管（狭窄后区域）中的红细胞速度。在休息条件下，PAOD患者的手指甲中的毛细血管已经大大低于健康受试者的毛细血管。脚趾毛细血管中的循环也是如此。此外，脚趾毛细血管在静息条件下的红细胞速度明显低于手指​​毛细血管。在闭塞后充血的持续时间和最大速度方面发现了相似的结果。结论是，PAOD患者在静息状态下以及手指和趾甲毛细血管闭塞后充血期间的皮肤微循环静息血流均受到损害。