骨水泥空心椎弓根螺钉短节段固定术治疗骨质疏松症腰椎滑脱症的临床疗效。,Scientific Reports

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骨水泥空心椎弓根螺钉短节段固定术治疗骨质疏松症腰椎滑脱症的临床疗效。
Scientific Reports ( IF 3.8 ) Pub Date : 2020-03-03 , DOI: 10.1038/s41598-020-60980-w
Yao-Yao Liu ₁ , Jun Xiao ₂ , Xiang Yin ₁ , Ming-Yong Liu ₁ , Jian-Hua Zhao ₁ , Peng Liu ₁ , Fei Dai ₂

Affiliation

许多临床研究表明，在骨质疏松性脊柱中使用骨水泥增强椎弓根螺钉治疗令人满意的临床疗效，但是，很少有研究涉及这种类型的螺钉在腰椎滑脱中的应用。这项研究旨在调查骨水泥注射空心椎弓根螺钉（CICPS）在腰椎滑脱合并骨质疏松症的中期临床疗效。2011年至2015年，本研究纳入了23例使用CICPS进行腰椎滑脱的腰椎间盘融合症（TLIF）。用Oswestry残疾指数（ODI）和视觉模拟量表（VAS）评估功能恢复和身体疼痛。分别记录手术时间，失血量和住院时间。进行腰椎X线计算机断层摄影术，以评估椎间盘间隙高度的损失，固定松动和骨融合率。23例患者的平均随访时间为22.5±10.2个月（范围6-36个月）。根据VAS和ODI评分，术后疼痛感和活动功能得到显着改善（p <0.05）。椎间盘间隙的高度减少了0.4±1.1 mm，并且植骨融合率为100％。没有观察到内部固定松动或螺钉拔出的情况。使用水泥增强的CICPS可能建议作为腰椎滑脱性骨质疏松患者的可行手术技术。6-36个月）。根据VAS和ODI评分，术后疼痛感和活动功能得到显着改善（p <0.05）。椎间盘间隙的高度减少了0.4±1.1 mm，并且植骨融合率为100％。没有观察到内部固定松动或螺钉拔出的情况。使用水泥增强的CICPS可能建议作为腰椎滑脱性骨质疏松患者的可行手术技术。6-36个月）。根据VAS和ODI评分，术后疼痛感和活动功能得到显着改善（p <0.05）。椎间盘间隙的高度减少了0.4±1.1 mm，并且植骨融合率为100％。没有观察到内部固定松动或螺钉拔出的情况。使用水泥增强的CICPS可能建议作为腰椎滑脱性骨质疏松患者的可行手术技术。

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Clinical efficacy of Bone Cement-injectable Cannulated Pedicle Screw Short Segment Fixation for Lumbar Spondylolisthesis with Osteoporosise.

Many clinical studies have shown a satisfactory clinical efficacy using bone cement-augmented pedicle screw in osteoporotic spine, however, few studies have involved the application of this type of screw in lumbar spondylolisthesis. This study aims to investigate the mid-term clinical outcome of bone cement-injectable cannulated pedicle screw (CICPS) in lumbar spondylolisthesis with osteoporosis. From 2011 to 2015, twenty-three patients with transforminal lumbar interbody fusion (TLIF) using CICPS for lumbar spondylolisthesis were enrolled in the study. Oswestry Disability Index (ODI) and Visual Analogue Scale (VAS) were used to evaluate faunctional recovery and physical pain; and operation time, blood loss and hospitalization time were recorded, respectively. Radiograph and computed tomography of lumbar spine was performed to assess loss of the intervertebral disc space height, fixation loosening, and the rate of bony fusion. The average follow-up time of 23 patients was 22.5 ± 10.2 months (range, 6-36 months). According to VAS and ODI scores, postoperative pain sensation and activity function were significantly improved (p < 0.05). The height of the intervertebral disc space was reduced by 0.4 ± 1.1 mm, and the bone graft fusion rate was 100%. No cases of internal fixation loosening or screw pullout was observed. CICPS using cement augmentation may suggest as a feasible surgical technique in osteoporotic patients with lumbar spondylolisthesis.

更新日期：2020-03-03

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