A Coumarin‐Based Fluorescent Probe for the Detection of Hypochlorite Ions and Its Applications in Test Paper and Cell Imaging
ChemistrySelect Pub Date : 2020-08-04  , DOI: 10.1002/slct.202002258                                                                                        
Ya Xie, Cuiping Zhou, Shiqing Zhang, Liqiang Yan, Xiongzhi Wu, Yang Shan

A turn on fluorescence probe was designed cleverly and synthesized simply through the condensation reaction between coumarin derivative and barbiturate, for sensitively specific recognition of hypochlorite ion (ClO⁻). This probe displayed a transient monitor process (about 5 min) to ClO⁻ in a wide range of pH values (3‐10), and the monitor limit could be estimated as low as 0.73μM. What's more, this probe could perform fluorescence imaging of ClO⁻ in living cells, and make ClO⁻ in aqueous solution appear on the convenient test strip visually.