研究方向：多功能抗肿瘤金属化合物

在读期间发表论文：

1. Man XY, Li WJ, Zhu MH, Li SH, Xu G, Zhang ZL, Yang F*, Liang H*. Anticancer tetranuclear Cu(I) complex catalyzes a click reaction to synthesize a chemotherapeutic agent in situ to achieve targeted dual-agent combination therapy for cancer. Angewandte Chemie-International Edition, 2024, DOI:10.1002/anie.202411846.

2. Man XY, Li WJ, Zhu MH, Li SH, Xu G, Zhang ZL, Liang H*, Yang F*. Rational design of a hetero-multinuclear gadolinium(III)-copper(II) complex: integrating magnetic resonance imaging, photoacoustic imaging, mild photothermal therapy, chemotherapy and immunotherapy of cancer. Journal of Medicinal Chemistry, 2024, 67, 15606–15619.

3. Man XY, Li SH, Xu G, Li WJ, Zhu MH, Zhang ZL, Liang H*, Yang F*. Developing a copper(II) isopropyl 2-pyridyl ketone thiosemicarbazone compound based on the IB subdomain of human serum albumin–indomethacin complex: inhibiting tumor growth by remodeling the tumor microenvironment. Journal of Medicinal Chemistry, 2024, 67, 5744–5757.

4. Man XY#, Yang TF#, Li WJ, Li SH, Xu G, Zhang ZL, Liang H*, Yang F*. Developing a gadolinium(III) compound based on apoferritin for targeted magnetic resonance imaging and dual-modal therapy of cancer. Journal of Medicinal Chemistry, 2023, 66: 7268–7279.

5. Zhu MH#, Man XY#, Yang TF, Li WJ, Li SH, Xu G, Zhang ZL, Liang H*, Yang F*. Developing a hetero-trinuclear erbium(III)-copper(II) complex based on apoferritin: targeted photoacoustic imaging and multi-modality therapy of tumor. Journal of Medicinal Chemistry, 2023, 66, 15424−15436.

6. Man XY, Sun ZW, Li SH, Xu G, Li WJ, Zhang ZL, Liang H*, Yang F*. Development of a platinum(II) compound based on indocyanine green@human serum albumin nanoparticles: integrating phototherapy, chemotherapy, and immunotherapy to overcome tumor cisplatin resistance. Rare Metals, 2024, https://doi.org/10.1007/s12598-024-02759-w.

学习经历：

2020/09-至今，广西师范大学化学与药学学院(博士在读)

2010/09-2013/06，中南大学化学化工学院(硕士)

2006/09-2010/06，吉首大学化学化工学院(学士)

工作经历：

2013/07-至今，遵义医科大学药学院(教师)

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