姚鸿，男，1989年出生，中国药科大学药物化学专业副研究员，硕士生导师。2013年获中国药科大学基础药学理科基地班专业学士学位，2018年获中国药科大学药物化学专业博士学位，同年留校于药学院药化系做师资博士后，2021年晋升为副研究员。

从事研究方向为药物化学、化学生物学及药物设计学，针对肿瘤、心脑血管疾病、神经退行性疾病开展创新小分子药物设计以及药物合成新技术研究。近年来以第一作者身份在Journal of Medicinal Chemistry、European Journal of Medicinal Chemistry、Chemical Communications等专业领域国际著名刊物上发表SCI收录论文10篇；作为课题负责人主持了国家自然科学基金青年基金项目一项，江苏省青年基金项目一项，江苏省博士后日常科研资助一项，博士后面上项目一项，参与国家自然科学基金面上项目２项。

联系方式：hyao1989@sina.cn

代表性论文：

1.      Hong Yao,^# Giuseppe Uras,^# Pengfei Zhang,# Shengtao Xu, Ying Yin, Jie Liu, Shuai Qin, Xinuo Li, Stephanie Allen, Renren Bai, Qi Gong, Haiyan Zhang,* Zheying Zhu,* and Jinyi Xu*. Discovery of Novel Tacrine−Pyrimidone Hybrids as Potent Dual AChE/GSK‑3 Inhibitors for the Treatment of Alzheimer’s Disease. J. Med. Chem. 2021, 64, 7483−7506.

2.      Hong Yao , Shaowen Xie, Xiaoqian Ma, Junkai Liu, Hongyu Wu, Aijun Lin, Hequan Yao, Dahong Li, Shengtao Xu*, Dong-Hua Yang, Zhe-Sheng Chen, Jinyi Xu*. Identification of a Potent Oridonin Analogue for Treatment of Triple-Negative Breast Cancer. J. Med. Chem. 2020, 63, 8157−8178.

3.      Hong Yao^#, Shanshan Luo^#, Junkai Liu, Shaowen Xie, Yanpeng Liu, Jinyi Xu*, Zheying Zhu, Shengtao Xu*. Controllable Thioester-based Hydrogen Sulfide Slow-Releasing Donors as Cardioprotective Agents. Chem. Commun., 2019, 55, 6193-6196.

4.      Hong Yao, Feijie Xu, Guangyu Wang, Shaowen Xie, Wenlong Li, Hequan Yao, Cong Ma, Zheying Zhu, Jinyi Xu*, Shengtao Xu*. Design, Synthesis, and Biological Evaluation of Truncated Deguelin Derivatives as Hsp90 Inhibitors. Eur. J. Med. Chem, 2019, 167, 485-498.

5.      Hong Yao, Guoxiang Wei, Yanpeng Liu, Hequan Yao, Zheying Zhu, Wencai Ye, Xiaoming Wu, Jinyi Xu*, Shengtao Xu*. Synthesis, Biological Evaluation of Fluorescent 23-Hydroxybetulinic Acid Probes, and Their Cellular Localization Studies. ACS Med. Chem. Lett., 2018, 9, 1030-1034.