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徐盛涛 副研究员 博士生导师    

徐盛涛,男,19875月生,副研究员,硕士生导师。2010年本科毕业于中国药科大学制药工程专业,2015年获得中国药科大学药物化学专业博士学位,同年留校于药学院药物化学系担任师资博士后,20184月获聘为特聘副研究员,20206月转为副研究员。

主要研究方向为针对肿瘤、心脑血管疾病、神经退行性疾病开展创新小分子药物设计以及药物合成新技术研究。作为课题负责人主持了国家自然科学基金面上项目一项,青年基金项目一项,博士后面上项目一项,博士后特别资助一项。共发表SCI论文50余篇,其中以第一作者或通讯作者在学科权威杂志Journal of Medicinal Chemistry, European Journal of Medicinal Chemistry, Green ChemistryJournal of Natural Products等发表论文20余篇。获得授权专利10项。


联系方式:13601402481cpuxst@163.comcpuxst@cpu.edu.cn


近期代表性论文:

  1. Hong Yao, Shaowen Xie, Xiaoqian Ma, Junkai Liu, Hongyu Wu, Aijun Lin, Hequan Yao, Dahong Li, Shengtao Xu*, Dong-Hua Yang, Zhe-Sheng Chen, Jinyi Xu*. Identification of a potent oridonin analogue for treatment of triple-negative breast cancer. J. Med. Chem. 2020, 63:8157-8178. (IF=6.205)

  2. Junkai Liu, Hong Yao, Xinnan Li, Hongyu Wu, Aijun Lin, Hequan Yao, Jinyi Xu*Shengtao Xu*. Organocatalytic 1,5-trifluoromethylthio-sulfonylation of vinylcyclopropane mediated by visible light in the water phase. Org. Chem. Front. 2020, 7:1314-1320. (IF=5.155)

  3. Shanshan Luo#Shengtao Xu#, Junkai Liu, Fenfen Ma, Yi Zhun Zhu*. Design and synthesis of novel SCM-198 analogs as cardioprotective agents: Structure-activity relationship studies and biological evaluations. Eur. J. Med. Chem.2020, 200: 112469. (IF=5.572)

  4. Hong Yao, Shanshan Luo, Junkai Liu, Shaowen Xie, Yanpeng Liu, Jinyi Xu*, Zheying Zhu, Shengtao Xu*.Controllable thioester-based hydrogen sulfide slow-releasing donors as cardioprotective agents.Chem. Commun.2019, 55: 6193-6196. (IF=5.996)

  5. Wenlong Li, Feijie Xu, Wen Shuai, Honghao Sun, Hong Yao, Cong Ma, Shengtao Xu*, Hequan Yao, Zheying Zhu, Dong-Hua Yang, Zhe-Sheng Chen, Jinyi Xu*. Discovery of novel quinoline-chalcone derivatives as potent antitumor agents with microtubule polymerization inhibitory activity. J. Med. Chem.2019,62:993-1013. (IF=6.054)