Our research is focused primarily upon the development of new strategies and methodologies for the synthesis of complex nitrogen heterocycles, including complex pyridine and quinoline derivatives, dihydropyridine and dihydroquinoline derivatives, tetrahydropyridine and tetrahydroquinoline derivatives, et al. We have successfully established mild and efficient methods for a series of biologically active nitrogen heterocycles, such as azacoumarins azachromones, azabenzofurans, azaindoles, et al.