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李祥瑞 进组时间: 2018    离组时间: 2021

·学习及工作经历:

2009.09–2013.06 淮海工学院 学士

2013.07–2018.08 南京正济医药研究有限公司 有机合成研究员

2018.09–2021.06 南京工业大学 硕士

2021.07–至今  南京赛斯赛克医药科技有限公司 总经理     


·邮箱:lixiangrui110@163.com


·发表成果:

(1) Stereoselective synthesis of fluoroalkylated (Z)-alkene via nickel-catalyzed and iron-mediated fluoroalkylation of alkynes

        Xiang-Rui Li, Wen-Xin Li, Zi-Lun Yu, Chuanji Shen, Xiaocong Zhou,* Xue-Qiang Chu, Weidong Rao, Zhi-Liang Shen*

      Org. Chem. Front. 20218, 6377-6383.

(2) Iron(0)-mediated Reformatsky Reaction for the Synthesis of β-Hydroxyl Carbonyl Compounds

      Xuan-Yu Liu,# Xiang-Rui Li,# Chen Zhang, Xue-Qiang Chu, Weidong Rao, Teck-Peng Loh,* and Zhi-Liang Shen* (# Equal contribution)

      Org. Lett. 2019, 21, 5873-5878.

(3) Indium-Mediated Difunctionalization of Iodoalkyl-Tethered Unactivated Alkenes via an Intramolecular Cyclization  and an Ensuing Palladium-Catalyzed 

      Cross-Coupling Reaction with Aryl Halide

      Xuan-Di Song, Xiang-Rui Li, Ya-Wen Wang, Xue-Qiang Chu, Weidong Rao, Haiyan Xu, Guo-Zhi Han,* and Zhi-Liang Shen*

      Org. Chem. Front. 2020, 7, 2703-2709.

(4) Iron(0)-mediated Henry-type Reaction of Bromonitromethane with Aldehydes for the Efficient Synthesis of 2-Nitro-alkan-1-ols.

      Si-Xuan Zhang, Xiang-Rui Li, Wen-Xin Li, Wei-Dong Rao, Danhua Ge*, Zhi-Liang Shen, Xue-Qiang Chu*.

      Chin. J. Org. Chem. 2021, 41, 235-241.

  (5)一种镍催化铁介导的炔烃氟代烷基化合成(Z)-烯烃的方法及产物;ZL202110827235.8 (CN113548968B);沈志良,褚雪强,王雅文,李祥瑞。