研究兴趣：植物内生真菌天然产物的生物合成途径解析

文章发表：

1. H.B. Xu^#, Z.B. Yuan^#, S. Yang^#, Z.P. Su, X.D. Hou, Z.W. Deng, Y. Zhang, Y.J. Rao*, Discovery of a fungal P450 with an unusual two-step mechanism for constructing bicyclo[3.2.2]nonane skeleton, 2024, JACS, accepted.

2. X.D. Hou^#, H.B. Xu^#, Z.W. Deng, Y.J. Yan, Z.B. Yuan, X.Z. Liu, Z.P. Su, S. Yang, Y. Zhang, Y.J. Rao*, Discovery of the Biosynthetic Pathway of Beticolin 1 Reveals a Novel Non-heme Iron-dependent Oxygenase for Anthraquinone Ring Cleavage, Angew, 2022, online.

3. X.D. Hou#, H.B. Xu# Z.B. Yuan, Z.W. Deng, K. Fu, Y. Gao, C.M. Liu, Y. Zhang, Y.J. Rao*, Structural analysis of an anthrol reductase inspires enantioselective synthesis of enantiopure hydroxycycloketones and β-halohydrins, Nature Communications, Accepted, 2023.

4. X.Z. Liu, Z.B. Yuan, H. Su, X.D. Hou, Z.W. Deng, H.B. Xu, B.D. Guo, D.J. Yin, X. Sheng, Y.J. Rao*, Molecular Basis of the Unusual Seven-membered Methylenedioxy Bridge Formation Catalyzed by Fe(II)/α-KG-dependent Oxygenase CTB9, ACS Catal, Accepted.

5. T.G. Zhou, S.Y. Yu, H.B. Xu, H.L. Liu, Y.J. Rao*,, Stimulating fungal cell wall integrity by exogenous β-glucanase to improve the production of fungal natural products, 2022, Applied Microbiology and Biotechnology, Accepted

6. Z.B. Yuan, H.B. Xu, Y. Zhang, Y.J. Rao*, Biosynthetic Pathways of Dimeric Natural Products Containing Bisanthraquinone and Related Xanthones, ChembioChem, 2023.