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杨子默 博士生     进组时间: 2016.09

学习经历:2012.09-2016.06  山东大学

                 2016.09-至今  清华大学药学院博士研究生


邮箱:yzm16@mails.tsinghua.edu.cn


研究方向:蛋白质降解技术


已发表论文:

Gao, H.; Yang, Z.; Yang, X.; Rao, Y. Synthesis and evaluation of osimertinib derivatives as potent EGFR inhibitors. Bioorganic & Medicinal Chemistry 2017, 25, 4553-4559.

Su, S.; Yang, Z.; Gao, H.; Yang, H.; Zhu, S.; An, Z.; Wang, J.; Li, Q.; Chandarlapaty, S.; Deng, H.; Wu, W.; Rao, Y. Potent and Preferential Degradation of CDK6 via Proteolysis Targeting Chimera Degraders. Journal of Medicinal Chemistry 2019,.

Yang, X.; Chen, X.; Yang, Z.; Xi, Y.; Wang, L.; Wu, Y.; Yan, Y.; Rao, Y. Synthesis, Evaluation, and Structure–Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation. Journal of Medicinal Chemistry 2018, 61, 8693-8706.