教育经历：

2012/08-2015/06，天津大学，化工学院，博士，导师：Victor C. Yang

2006/08-2009/06，清华大学 & 北京协和医学院，生物药剂学，硕士，

2002/09-2006/07，天津大学，材料科学与工程学院，学士。

科研与学术工作经历：

2016/10-至今，清华大学，药学院，博士后，合作导师：钱锋； 

2015/07-2016/10，天津大学，天津化学化工协同创新中心，专任副研究员；

2011/09-2012/08, 中国科学院上海药物研究所，药物制剂中心，技术员；

2009/07-2011/03，亚宝药业集团北京药物研究院，药物分析室，研发人员。

主持或参加科研项目（课题）及人才计划项目情况（按时间倒序排序）：

1. 博士后基金委面上一等资助项目，基于细胞代谢调控实现KRAS基因突变胰腺癌靶向药物递送（2017M610094），在研，项目负责人；

2. 天津市临床药物关键技术重点实验室开放课题，基于温度响应的DNA Linker的构建及其在药物传递系统中的应用（CTD2016-03），在研，项目负责人；

3. 自然科学基金青年科学基金项目，基于肿瘤靶向及特异性激活的“前药”性大分子药物给药系统治疗结肠癌的研究（81402856），结题，项目参与人;

已发表学术论文（期刊论文）

# Co-first author

1. Junxiao Ye^#, Xing Pei^#, Hui Cui, Zhili Yu, Hyukjin Lee, Jianxin Wang, Xu Wang, Lu Sun, Huining He*, Victor C. Yang, Cellular uptake mechanism and comparative in vitro cytotoxicity studies of monomeric LMWP-siRNA conjugate, Journal of Industrial & Engineering Chemistry,63 (2018) 103-111. (IF:4.421)
2. Junxiao Ye, Ergang Liu, Junbo Gong, Jianxin Wang, Yongzhuo Huang, Huining He*, Victor C. Yang*, High-Yield Synthesis of Monomeric LMWP(CPP)-siRNA Covalent Conjugate for Effective Cytosolic Delivery of siRNA, Theranostics, 7 (2017) 2495-2508. (IF:8.76)
3. Zhili Yu^#, Junxiao Ye^#, Xing Pei, Lu Sun, Ergang Liu, Jianxin Wang, Yongzhuo Huang, Seung Jin Lee, Huining He*, Improved method for synthesis of low molecular weight protamine–siRNA conjugate, Acta Pharmaceutica Sinica B, 8 (2018) 116-126. (IF: 6.014)
4. Junxiao Ye^#, Ergang Liu^#, Zhili Yu, Xing Pei, Sunhui Chen, Pengwei Zhang, Meong Cheol Shin, Junbo Gong, Huining He*, Victor C. Yang*, CPP-Assisted Intracellular Drug Delivery, What Is Next?, International Journal of Molecular Sciences, 17 (2016) 1892. (IF:3.226)
5. Junxiao Ye^#, Meong Cheol Shin^#, Qiuling Liang, Huining He*, Victor C. Yang*, 15 years of ATTEMPTS: A macromolecular drug delivery system based on the CPP-mediated intracellular drug delivery and antibody targeting, Journal of Controlled Release, 205 (2015) 58-69. (IF:7.786)
6. Huining He^#, Junxiao Ye^#, Ergang Liu, Qiuling Liang, Quan Liu, Victor C. Yang*, Low molecular weight protamine (LMWP): a nontoxic protamine substitute and an effective cell-penetrating peptide, Journal of Controlled Release, 193 (2014) 63-73. (IF:7.786)
7. Huining He^#, Junxiao Ye^#, Yinsong Wang, Quan Liu, Hee Sun Chung, Young Min Kwon, Meong Cheol Shin, Kyuri Lee, Victor C Yang*, Cell-penetrating peptides meditated encapsulation of protein therapeutics into intact red blood cells and its application, Journal of Controlled Release, 176 (2014) 123-132. (IF:7.786)
8. Junxiao Ye, Huining He*, Junbo Gong, Weibing Dong, Yongzhuo Huang, Jianxin Wang, Guanyi Chen, Victor C. Yang*. Ultrasound-mediated targeted microbubbles: a new vehicle for cancer therapy, Frontiers of Chemical Science & Engineering, 7 (2013) 20-28. (IF:1.712)
9. Junxiao Ye, Wang Wei, Li Hui Quan, Chun Yu Liu, Qi Chang, Yong Hong Liao*, An LC–MS/MS method for the simultaneous determination of chlorogenic acid, forsythiaside A and baicalin in rat plasma and its application to pharmacokinetic study of Shuang-huang-lian in rats, Journal of Pharmaceutical & Biomedical Analysis, 52 (2010) 625-630. (IF:3.255)
10. Pengwei Zhang, Junxiao Ye, Ergang Liu, Lu Sun, Jiacheng Zhang, Seung Jin Lee, Junbo Gong*, Huining He*, Victor C. Yang*, Aptamer-coded DNA nanoparticles for targeted doxorubicin delivery using pH-sensitive spacer, Frontiers of Chemical Science & Engineering, 11 (2017) 1-8. (IF:1.712)
11. Sunhui Chen^#, Qiuling Liang^#, Ergang Liu, Zhili Yu, Lu Sun, Junxiao Ye, Meong Cheol Shin, Jianxin Wang, Huining He*, Curcumin/sunitinib co-loaded BSA-stabilized SPIOs for synergistic combination therapy for breast cancer, Journal of Materials Chemistry B, 5 (2017) 4060-4072. (IF:4.543)
12. Huining He^#, Lu Sun^#, Junxiao Ye, Ergang Liu, Sunhui Chen, Qiuling Liang, Meong Cheol Shin, Victor C. Yang*, Enzyme-triggered, cell penetrating peptide-mediated delivery of anti-tumor agents, Journal of Controlled Release, 240 (2016) 67-76. (IF:7.786)
13. Rongbao Qi, Jingkang Wang, Junxiao Ye, Hongxun Hao*, Ying Bao, The solubility of cefquinome sulfate in pure and mixed solvents, Frontiers of Chemical Science & Engineering, 10 (2016) 245-254. (IF:1.712)
14. Ergang Liu, Jianyong Sheng, Junxiao Ye, Y. Wang, Junbo Gong, Victor C. Yang*, Jianxin Wang, Huining He*, CPP mediated insulin delivery: current status and promising future, Curr Pharm Biotechnol, 15 (2014) 240-255.( IF:2.459)
15. Huining He, Qiuling Liang, Meong Cheol Shin, Kyuri Lee, Junbo Gong, Junxiao Ye, Quan Liu, Jingkang Wang, Victor Yang*, Significance and strategies in developing delivery systems for bio-macromolecular drugs, Frontiers of Chemical Science & Engineering, 7 (2013) 496-507. (IF:1.712)
16. Huining He, Junxiao Ye, Jianyong Sheng, Jianxin Wang, Yongzhuo Huang,  Guanyi Chen, Jingkang Wang, Victor C. Yang*.Overcoming oral insulin delivery barriers: application of cell penetrating peptide and silica-based nanoporous composites, Frontiers of Chemical Science & Engineering, 7 (2013) 9-19. (IF:1.712)
17. Yongxin Yang, Yifan Jiang, Zhao Wang, Jinhua Liu, Lu Yan, Junxiao Ye, Yongzhuo Huang*, Skin-permeable quaternary nanoparticles with layer-by-layer structure enabling improved gene delivery, Journal of Materials Chemistry B, 22 (2012) 10029-10034. (IF: 4.543)
18. Rong Han, Junxiao Ye, Lihui Quan, Chunyu Liu, Ming Yang, Yonghong Liao*, Evaluating pulmonary toxicity of Shuang-Huang-Lian in vitro and in vivo, Journal of Ethnopharmacology, 135 (2011) 522-529. (IF:2.981)
19. Xiaobin Liu, Junxiao Ye, Lihui Quan, Chunyu Liu, Xuliang Deng, Ming Yang, Yonghong Liao*, Pulmonary delivery of scutellarin solution and mucoadhesive particles in rats, European Journal of Pharmaceutics & Biopharmaceutics, 70 (2008) 845-852. (IF:4.159)

联系邮箱：yjx0902@126.com