教育经历
2007年9月-2011年7月,中南民族大学药学院 药学专业学士学位
2011年9月-2014年7月,暨南大学药学院 药物化学专业硕士学位
2015年9月-2019年7月,清华大学药学院 生物学专业博士学位
工作经历
2014年8月-2015年8月,清华大学医学院 研究助理
2019年9月-至今,在五邑大学药学与食品工程学院从事教学、科研工作
科研方向
药物化学---神经退行性疾病药物的研发
有机化学---氮杂环卡宾催化的反应研究
科研项目
五邑大学高层次引进人才启动经费,氮杂环卡宾催化的β位官能团化反应研究,100万元,2019.09-2024.08,主持。
发表文章
Shaofa Sun, # Ming Lang, # Jian Wang.* N-Heterocyclic Carbene-Catalyzed β-Indolylation of α- Bromoenals with Indoles. Adv. Synth. Catal. 2019, DOI: 10.1002/adsc.201900699.
Ming Lang and Wang Jian*. A carbene-catalyzed tandem isomerization/cyclisation strategy: an efficient assembly of benzoxazinones. Org. Chem. Front. 2019, 6, 1367-1371.
Jianbo Bie, Ming Lang, Jian Wang.* Enantioselective N-Heterocyclic Carbene-Catalyzed Kinetic Resolution of Anilides. Org. Lett. 2018, 20, 5866-5871.
Ming Lang,# Qianfa Jia,# Jian Wang.* N-Heterocyclic Carbene-Catalyzed Annulation of Ylides with Ynals: Direct Access to α-Pyrones. Chem. Asian J. 2018, 13, 2427-2430.
Ming Lang and Jian Wang.* N‐Heterocyclic Carbene‐Catalyzed Enantioselective β‐Amination of α‐Bromoenals Enabled by a Proton‐Shuttling Strategy. Eur. J. Org. Chem. 2018, 2958-2962.
Jicheng Wu, Ming Lang, Jian Wang.* Photoredox-Catalyzed Cross-Coupling of Enamides for the Assembly of β-Difluoroimine Synthons. Org. Lett. 2017, 19, 5653-5656
Qianfa Jia, Dongli Li, Ming Lang, Kun Zhang, Jian Wang.* 4‐Dimethylaminopyridine‐Mediated [3+3] Cycloaddition of Aza‐oxyallyl Cations and Nitrones. Adv. Synth. Catal. 2017, 359, 3837-3842.
Wenjun Li, Manjaly J. Ajitha, Ming Lang, Kuo-Wei Huang,* Jian Wang.* Catalytic Intermolecular Cross-Couplings of Azides and LUMO-Activated Unsaturated Acyl Azoliums. ACS Catal. 2017, 7, 2139-2144.
Lei Wang, Jianwei Zhang, Ming Lang, Jian Wang.* Palladium-catalyzed ring contraction reaction of naphthoquinones upon reaction with alkynes. Org. Chem. Front. 2016, 3, 603-608.
Zheng Liu, Wei Cai, Ming Lang, Ruizuo Yan, Zhenshen Li, Gaoxiao Zhang, Pei Yu, Yuqiang Wang, Yewei Sun.* Neuroprotective Effects and Mechanisms of Action of Multifunctional Agents Targeting Free Radicals, Monoamine Oxidase B and Cholinesterase in Parkinson’s Disease Model. J. Mol. Neurosci. 2017, 61, 498-510.
Wei Liu, Ming Lang, Moussa B.H. Youdim, Tamar Amit, Yewei Sun, Zaijun Zhang, Yuqiang Wang, Orly Weinreb.* Design, synthesis and evaluation of novel dual monoamine-cholinesterase inhibitors as potential treatment for Alzheimer's disease. Neuropharmacology. 2016, 109, 376-385.
Ming Lang,# Hui Yao,# Pengfei Fu, Wei Cai, Yuqiang Wang, Pei Yu.* An unexpected replacement of a methyl with an amino in the tetramethylpyrazine system. Res. Chem. Intermed. 2015, 41, 5621-5626.
Ming Lang, Ruizuo Yan, Yuqiang Wang, Pei Yu.* A Selective O- and N-Acylation Protocol for Carbamyl Chloride. Chin. J. Org. Chem. 2014, 34, 1227-1230.
Daping Xu, Hongwei Duan, Zaijun Zhang*, Wei Cui, Liang Wang, Yewei Sun, Ming Lang, Pui Man Hoi, Yifan Han, Yuqiang Wang, Simon MingYuen Lee*. The Novel Tetramethylpyrazine Bis-nitrone (TN-2) Protects Against MPTP/MPP+-Induced Neurotoxicity via Inhibition of Mitochondrial-Dependent Apoptosis. J. Neuroimmune. Pharmacol. 2014, 9, 245-258.
Pei Yu, Longfei Xia, Jing Zhao, Gaoxiao Zhang, Zaijun Zhang, Ming Lang, and Yuqiang Wang*. Synthesis and Preliminary Anticancer Evaluation of 10-Hydroxycamptothecin Analogs. Biol. Pharm. Bull. 2012, 35, 1295-1299.
专利申请
汪舰, 别建波, 郎明. 一种含氮杂环化合物及其制备方法与在抑制激酶活性中的应用. 申请号: 2016110219387.
陈立功, 程丽丽, 梁宇, Yueming Li, 汪舰, 郎明. 双胍类探针及其制备方法. 申请号: 2017105644761.
汪舰, 郎明, 钟毅, 马伟伟, 杜书文. 一类3,5-二取代乙内酰脲类化合物及其制备方法与应用. 申请号: 2018105997147.
王玉强, 穆萨·B·H·尤迪姆, 孙业伟, 张在军, 张高小, 于沛, 易鹏 , 郎明, 刘伟. 一种具有神经保护作用的化合物及其制备方法和应用. 申请号: CN201410033815.(已授权)