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2020年06月23日,祝贺付建冶博士文章被Coordination Chemistry Reviews期刊接收!
发布时间:2020-10-10

付建冶博士在Coordination Chemistry Reviews期刊上发表题为“Janus nanoparticles for cellular delivery chemotherapy: Recent advances 

and challenges”(https://doi.org/10.1016/j.ccr.2020.213467)的文章,文章摘要如下:



Abstract


Anisotropic Janus nanoparticles have been widely investigated in recent years on both the nanoparticles preparation strategies and the advanced applications. Janus 

nanoparticles possess biphasic geometry of distinct compositions or asymmetric morphologies that bring distinct novel properties. Janus nanoparticles have been 

widely used in various applications such as catalysts, nanomotors, and nanomedicine. In biomedical fields, the special spatially separated surface chemistry of Janus 

nanoparticles provides efficient targeting and delivery capability, which can be used to design next generation delivery vectors. Moreover, the unique asymmetric 

morphology of Janus nano-particles exhibits unusual behaviours when internalized by cells. Janus nanoparticles can be developed as new probes to investigate the 

nanoparticlecell interaction during the critical cellular delivery processes. This review focuses on recent progress of the design and synthesis of novel Janus 

nanoparticles and their unusual performance in cellular delivery related applications. The advantages and new opportunities of Janus nanoparticles as cellular 

delivery vectors are discussed.