祝贺课题组张志豪同学的论文在Letters in Organic Chemistry刊物上发表
发布时间：2024-03-28
Ligand-Free, Copper-Catalyzed Coupling Reaction of Aryl Aluminum Reagents with N-Aryl Thiosuccinimides
Zhihao Zhang1,2,#, Xiaoying Jia1,2,#, Jiaxia Pu1,2, Lirong Han1,2, Jinsong Hou1,2 and Qinghan Li1,2,*
Abstract:
A highly efficient and simple cross-coupling reaction of
N
-aryl aluminum reagents with Naryl thiosuccinimides for the synthesis of diarylsulide derivatives using CuCl (20 mol%) as a catalyst is reported. Under the optimum reaction conditions, the coupling reaction between aryl aluminum reagents with different substituents and N-aryl thiosuccinimides with different substituents can be carried out smoothly with 18-94% isolated yields of diarylsulides. The method avoids the use of expensive transition metals, such as Pd, Ir, or Rh, phosphine ligands, and has the advantages of simple operation and high reaction efficiency. The structures of all the target compounds are confirmed by
1
HNMR and
13
CNMR.