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陶辉 在职博士后    

受教育经历

2017.09-2020.08    中国药科大学    临床药学  博士研究生

2009.09-2012.07    安徽医科大学    药理学     硕士研究生  

2005.09-2009.07    安徽医科大学    药学       本科  


工作经历

2023/06-至今   安徽医科大学第二附属医院    副教授、博士生导师

2022/10-至今   上海交通大学医学院             博士后(在职)

2012/07-至今   安徽医科大学第二附属医院     副研究员、硕士研究生导师


已发表论文

(*第一作者,#通讯作者)

(1)Sha Xu*; Hui Tao*; Wei Cao*; Li Cao; Yan Lin; Shi-Min Zhao; Wei Xu; Jing Cao; Jian-Yuan Zhao#; Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis, Signal Transduction and Targeted Therapy, 2021, 6(1): 54. IF=38.104 中科院1区(共同第一作者,排名第二)71次 

(2)Li-Chan Lin, Bin Tu, Kai Song, Zhi-Yan Liu, He Sun, Yang Zhou, Ji-Ming Sha, Jing-Jing Yang, Ye Zhang, Jian-Yuan Zhao, Hui Tao#. Mitochondrial quality control in cardiac fibrosis: Epigenetic mechanisms and therapeutic strategies. Metabolism-Clinical and Experimental, 2023, 145: 155626. IF=13.934 中科院1区 (通讯作者,The last)

(3)Ji-Ming Sha, Ren-Quan Zhang, Xian-Chen Wang, Yang Zhou, Kai Song, He Sun, Bin Tu, Hui Tao#. Epigenetic reader MeCP2 repressed WIF1 boosts lung fibroblast proliferation, migration and pulmonary fibrosis. Toxicology Letters, 2023, 381:1-12. IF=4.271 中科院2区(通讯作者,The last) 

(4)Rui Zhao*; Ke Cai*; Jing-Jing Yang*; Zhou Qian*; Wei Cao; Jie Xiang; Yi-Hui Shen; Lei-Lei Cheng; Wei-Dong Zang; Yan Lin; Yi-Yuan Yuan; Wei Xu; Hui Tao#; Shi-Min Zhao#; Jian-Yuan Zhao#; Nuclear ATR lysine-tyrosylation protects against heart failure by activating DNA damage response, Cell Reports, 2023. 42(4). 112400. IF=9.995中科院1区(共同通讯作者)

(5)Yang Zhou, Kai Song, Bin Tu, He Sun, Ji-Fei Ding, Yong Luo, Ji-Ming Sha, Rui Li, Ye Zhang, Jian-Yuan Zhao, Hui Tao#. METTL3 boosts glycolysis and cardiac fibroblast proliferation by increasing AR methylation. International Journal of Biological Macromolecules, 2022. 223: 899-915. IF=8.025中科院1区(通讯作者,The last) 

(6)He Sun, Kai Song, Yang Zhou, Ji-Fei Ding, Bin Tu, Jing-Jing Yang, Ji-Ming Sha, Jian-Yuan Zhao, Ye Zhang, Hui Tao#. MTHFR epigenetic derepression protects against diabetes cardiac fibrosis. Free Radical Biology and Medicine. 2022. 193: 330-341. IF=8.101中科院1区(通讯作者,The last) 

(7)Ji-Fei Ding, Yang Zhou, Sheng-Song Xu, Kai-Hu Shi, He Sun, Bin Tu, Kai Song, Hai-Yang Xuan, Ji-Ming Sha, Jian-Yuan Zhao, Hui Tao#. Epigenetic control of LncRNA NEAT1 enables cardiac fibroblast pyroptosis and cardiac fibrosis. European Journal of Pharmacology. 2023. 938: 175398. IF=5.195中科院2区(通讯作者,The last) 

(8)Ji-Fei Ding, He Sun, Kai Song, Yang Zhou, Bin Tu, Kai-Hu Shi, Dong Lu, Sheng-Song Xu, Hui Tao#. IGFBP3 epigenetic promotion induced by METTL3 boosts cardiac fibroblast activation and fibrosis. European Journal of Pharmacology. 2023. 942: 175494. IF=5.195中科院2区(通讯作者,The last) 

(9)Juan Wang, Yang Yang, Feng Sun, Yong Luo, Yan Yang, Jun Li, Wei Hu, Hui Tao#, Chao Lu#, Jing-Jing Yang#. ALKBH5 attenuates mitochondrial fission and ameliorates liver fibrosis by reducing Drp1 methylation. Pharmacological Research. 2023. 187: 106608. IF=10.334中科院1区(共同通讯)

(10)Jing-Jing Yang, Juan Wang, Yang Yang, Feng Sun, Yan Yang, Jun Li, Hui Tao#, Chao Lu#, Epigenetic control of mitochondrial fission enables hepatic stellate cells activation in liver fibrosis via PGC-1α-Drp1 pathway, Mitochondrion, 2022, 66: 38-50. IF=4.534中科院3区(共同通讯) 

(11)Hui Tao; Peng Shi; Xu-Dong Zhao; Hai-Yang Xuan#; Wen-Hui Gong#; Xuan-Sheng Ding#; DNMT1 deregulation of SOCS3 axis driver cardiac fibroblasts activation in diabetic cardiac fibrosis, Journal of Cellular Physiology, 2021, 236(5):3481-3494. IF=6.513 中科院1区 

(12)Hui Tao; Peng Shi; Xu-Dong Zhao; Hai-Yang Xuan#; Xuan-Sheng Ding#; MeCP2 inactivation of LncRNA GAS5 triggers cardiac fibroblasts activation in cardiac fibrosis, Cellular Signalling, 2020, 74:109705. IF=4.85 中科院2区 

(13)Hui Tao; Peng Shi; Hai-Yang Xuan#; Xuan-Sheng Ding#; DNA methyltransferase-1 inactivation of androgen receptor axis triggers homocysteine induced cardiac fibroblast autophagy in diabetic cardiac fibrosis, Archives of Biochemistry and Biophysics, 2020, 692: 108521. IF=4.114 中科院2区 

(14)Peng Shi*; Xu-Dong Zhao*; Kai-Hu Shi#; Xuan-Sheng Ding; Hui Tao#; MiR-21-3p triggers cardiac fibroblasts pyroptosis in diabetic cardiac fibrosis via inhibiting androgen receptor, Experimental Cell Research, 2021, 399(2):112464. IF=4.145 中科院3区

(15)Sheng-Song Xu; Ji-Fei Ding; Peng Shi; Kai-Hu Shi#; Hui Tao#; DNMT1-induced miR-152-3p suppression facilitates cardiac fibroblast activation in cardiac fibrosis, Cardiovascular Toxicology, 2021 Dec;21(12):984-999. IF=3.239 中科院3区 

(16)Qian She*; Peng Shi*; Sheng-Song Xu; Hai-Yang Xuan; Hui Tao#; Kai-Hu Shi#; Yan Yang#; DNMT1 Methylation of LncRNA GAS5 Leads to Cardiac Fibroblast Pyroptosis via Affecting NLRP3 Axis, Inflammation, 2020, 43(3):1065-1076. IF=4.657 中科院2区 

(17)Hui Tao; Jun-Ye Tao; Zheng-Yu Song; Peng Shi; Qin Wang; Zi-Yu Deng; Xuan-Sheng Ding#; MeCP2 triggers diabetic cardiomyopathy and cardiac fibroblast proliferation by inhibiting RASSF1A, Cellular Signalling, 2019, 63: 109387. IF=4.85 中科院2区  

(18)Hui Tao*; Chen Dai*; Ji-Fei Ding; Jing-Jing Yang; Xuan-Sheng Ding#; Sheng-Song Xu; Kai-Hu Shi#; Epigenetic aberrations of miR-369-5p and DNMT3A control Patched1 signal pathway in cardiac fibrosis, Toxicology, 2018, 410: 182-192. IF=4.571 中科院2区 

(19)Xu-Dong Zhao; Run-He Qin; Jing-Jing Yang; Sheng-Song Xu; Hui Tao#; Xuan-Sheng Ding; Kai-Hu Shi#; DNMT3A controls miR-200b in cardiac fibroblast autophagy and cardiac fibrosis, Inflammation Research, 2018, 67(8): 681-690. IF=6.986 中科院2区 

(20)Hui Tao*; Zheng-Yu Song*; Xuan-Sheng Ding#; Jing-Jing Yang; Kai-Hu Shi#; Jun Li; LncRNAs and miRs as epigenetic signatures in diabetic cardiac fibrosis: new advances and perspectives, Endocrine, 2018, 62(2): 281-291. IF=3.925 中科院3区 

(21)Hui Tao*; Zheng-Yu Song*; Xuan-Sheng Ding#; Jing-Jing Yang; Kai-Hu Shi#; Jun Li; Epigenetic signatures in cardiac fibrosis, special emphasis on DNA methylation and histone modification, Heart Failure Reviews, 2018, 23(5): 789-799. IF=4.654 中科院2区

(22)Hui Tao*; Jia-Gui Zhang*; Run-He Qin*; Chen Dai; Peng Shi; Jing-Jing Yang; Zi-Yu Deng#; Kai-Hu Shi#; LncRNA GAS5 controls cardiac fibroblast activation and fibrosis by targeting miR-21 via PTEN/MMP-2 signaling pathway, Toxicology, 2017, 386: 11-18. IF=4.571 中科院2区 

(23)Hui Tao*; Ze-Wen Chen*; Jing-Jing Yang; Kai-Hu Shi#; MicroRNA-29a suppresses cardiac fibroblasts proliferation via targeting VEGF-A/MAPK signal pathway, International Journal of Biological Macromolecules, 2016, 88: 414-423. IF=8.025 中科院1区

(24)Hui Tao; Jing-Jing Yang; Wei Hu; Kai-Hu Shi#; Zi-Yu Deng#; Jun Li; Noncoding RNA as regulators of cardiac fibrosis: current insight and the road ahead, Pflügers Archiv-European Journal of Physiology, 2016, 468(6): 1103-11. IF=4.458 中科院3区

(25)Hui Tao; Jing-Jing Yang#; Kai-Hu Shi; Jun Li#; Epigenetic factors MeCP2 and HDAC6 control α-tubulin acetylation in cardiac fibroblast proliferation and fibrosis, Inflammation Research, 2016, 65(5): 415-26. IF=6.986 中科院2区

(26)Hui Tao; Jing-Jing Yang#; Kai-Hu Shi#; Jun Li; Wnt signaling pathway in cardiac fibrosis: New insights and directions, Metabolism-Clinical and Experimental, 2016, 65(2): 30-40. IF=13.934 中科院1区

(27)Hui Tao; Jing-Jing Yang; Wei Hu; Kai-Hu Shi; Zi-Yu Deng#; Jun Li#; MeCP2 regulation of cardiac fibroblast proliferation and fibrosis by down-regulation of DUSP5, International Journal of Biological Macromolecules, 2016, 82: 68-75. IF=8.025 中科院1区

(28)Hui Tao; Kai-Hu Shi#; Jing-Jing Yang#; Jun Li; Epigenetic mechanisms in atrial fibrillation: New insights and future directions, Trends in Cardiovascular Medicine, 2016, 26(4): 306-18. IF=8.049 中科院2区

(29)Hui Tao; Jing-Jing Yang#; Kai-Hu Shi#; Non-coding RNAs as direct and indirect modulators of epigenetic mechanism regulation of cardiac fibrosis, Expert Opinion on Therapeutic Targets, 2015, 19(5):707-716. IF=6.902 中科院2区

(30)Hui Tao; Jing-Jing Yang#; Ze-Wen Chen; Sheng-Song Xu; Xiao Zhou; Hong-Ying Zhan; Kai-Hu Shi#; DNMT3A silencing RASSF1A promotes cardiac fibrosis through up-regulation of ERK1/2, Toxicology, 2014, 323: 42-50. IF=4.571 中科院2区

(31)Hui Tao*; Jing-Jing Yang*; Kai-Hu Shi#; Zi-Yu Deng#; Jun Li#; DNA methylation in cardiac fibrosis: New advances and perspectives, Toxicology, 2014, 323C: 125-129. IF=4.571 中科院2区

(32)Hui Tao; Kai-Hu Shi#; Jing-Jing Yang; Cheng Huang; Hong-Ying Zhan; Jun Li#; Histone deacetylases in cardiac fibrosis: current perspectives for therapy, Cellular Signalling, 2014, 26(3): 521-527. IF=4.85 中科院2区

(33)Hui Tao*; Jing-Jing Yang*; Jun Li#; MicroRNA-29a is a friend or foe for cardiac hypertrophy, Journal of the American College of Cardiology, 2014, 64(8):848-848. IF=27.203中科院1区

(34)Hui Tao*; Kai-Hu Shi*#; Jing-Jing Yang; Cheng Huang; Li-Ping Liu; Jun Li; Epigenetic regulation of cardiac fibrosis, Cellular Signalling, 2013, 25(9): 1932-1938. IF=4.85 中科院2区

(35)Kai-Hu Shi*#; Hui Tao*; Jing-Jing Yang; Jun-Xu Wu; Sheng-Song Xu; Hong-Ying Zhan; Role of microRNAs in atrial fibrillation: new insights and perspectives, Cellular Signalling, 2013, 25(11): 2079-2084. IF=4.85 中科院2区  

(36)Hui Tao; Kai-Hu Shi#; Jing-Jing Yang; Galectin-3, new potential therapeutic target for cardiac remodeling, European Journal of Heart Failure, 2013, 15(6): 709-709. IF=17.349 中科院1区

(37)Hui Tao, Jing-Jing Yang, Wei Hu#, Kai-Hu Shi #, Jun Li, HDAC6 Promotes Cardiac Fibrosis Progression through Suppressing RASSF1A Expression, Cardiology, 2016, 133(1): 18-26. IF=2.342   

(38)Hui Tao*, Meng Zhang*, Jing-Jing Yang#, Kai-Hu Shi#. MicroRNA-21 via Dysregulation of WW Domain-Containing Protein 1 Regulate Atrial Fibrosis in Atrial Fibrillation. Heart Lung and Circulation. 2018, 27(1):104-113. IF=2.975 中科院4区 

(39)Hui Tao*, Wei Cao*, Jing-Jing Yang, Kai-Hu Shi#, Xiao Zhou#, Li-Ping Liu, Jun Li. Long noncoding RNA H19 controls DUSP5/ERK1/2 axis in cardiac fibroblast proliferation and fibrosis. Cardiovascular Pathology. 2016, 25(5): 381-9. IF=3.975 中科院3区 

(40)Hui Tao, Cheng Huang, Jing-Jing Yang, Tao-Tao Ma, Er-Bao Bian, Lei Zhang, Xiong-Wen Lv, Yong Jin, Jun Li#. MeCP2 controls the expression of RASAL1 in the hepatic fibrosis in rats. Toxicology. 2011 Dec 18; 290(2-3):327-33. IF=4.571 中科院2区 

(41)Hui Tao, Wei Cao, Kai-Hu Shi#. The fibrosis biomarkers procollagen type III, N-terminal propeptide and transforming growth factor β1 as foes for patients with atrial fibrillation. American Heart Journal. 2014 Oct;168(4):e15. IF=5.099 中科院2区 

(42)Hui Tao, Jing-Jing Yang, Kai-Hu Shi#. Remote ischemic conditioning, a double-edged sword in left ventricular remodeling. International Journal of Cardiology. 2015 Feb 1;180:6. IF=4.164 中科院2区 

(43)Hui Tao, Jing-Jing Yang, Xiao Zhou#, Zi-Yu Deng, Kai-Hu Shi#, Jun Li. Emerging role of long noncoding RNAs in lung cancer: Current status and future prospects. Respiratory Medicine. 2016 Jan;110:12-9. IF=4.582 中科院3区 

(44) Hui Tao, Kai-Hu Shi#, Jing-Jing Yang. Platelet-derived growth factor, a novel potential therapeutic target for atrial fibrillation. Heart Rhythm. 2013 Jun;10(6):e71-2. IF=6.779 中科院2区 

(45)Xiao Zhou, Hui Tao#. Overexpression of microRNA-936 suppresses non-small cell lung cancer cell proliferation and invasion via targeting E2F2. Experimental and Therapeutic Medicine. 2018 Sep; 16(3):2696-2702. IF=2.751 中科院4区

(46)Yang Yang, Jing-Jing Yang, Hui Tao#, Wei-Sen Jin#. MicroRNA-21 controls hTERT via PTEN in human colorectal cancer cell proliferation. Journal of Physiology and Biochemistry. 2015 Mar; 71(1):59-68. IF=5.08 中科院2区

(47)Xiao-Hui Wang*, Sha Xu*, Xiang-Yu Zhou*, Rui Zhao, Yan Lin, Jing Cao, Wei- Dong Zang, Hui Tao, Wei Xu, Ming-Qing Li, Shi-Min Zhao, Li-Ping Jin#, and Jian-Yuan Zhao#. Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk. Nature Communications, 2021, 12(1): 3428. IF=17.694 中科院1区

(48)Dan Wang*, Feng Wang*, Kai-Hu Shi*, Hui Tao, Yang Li, Rui Zhao, Han Lu, Wenyuan Duan, Bin Qiao, Shi-Min Zhao, Hongyan Wang, Jian-Yuan Zhao. Lower Circulating Folate Induced by a Fidgetin Intronic Variant is Associated with Reduced Congenital Heart Disease Susceptibility. Circulation, 2017: 135(18):1733-1748. IF=39.918. 中科院1区