个人简介：
嵇豪 男，博士，2018年毕业于江南大学，获发酵工程专业工学博士学位。主要从事微生物代谢工程，生物化工及生物功能材料等领域的研究，重点关注工业微生物对环境压力的响应机制，及其在生物化工领域的应用等。近年来先后参与国家自然科学基金5项，主持浙江省自然科学基金项目及温州市科技局项目各1项，获得授权发明专利2项，累计发表学术论文19篇，其中以通讯或第一作者发表的SCI论文8篇。
科研项目：
1. 浙江省自然科学基金探索项目Q，LQ20C200015，极端酸性压力诱导库德毕赤酵母细胞形态发生的分子机制研究，2020/01-2022/12，10万元，在研，主持
2. 温州市基础性科研项目，2018G0178，多耐受酵母Pichia kudriavzevii低pH发酵生产D-木糖酸的关键技术研究，2019/01-2020/12，5万元，在研，主持
3. 国家自然科学基金面上项目，31972418，白菜花粉响应低温胁迫的lncRNA-BrCBF4-COR基因调控通路研究，2020/01-2023/12，56万元，在研，参加。
4. 国家自然科学基金面上项目，31570052，耐超高渗工业酵母的CgHOG 途径及其抗逆性应答转录调节研究，2016/01-2019/12，65万元，已结题，参加
5. 国家自然科学基金面上项目，31270061，紫色红曲菌色素和桔霉素合成关键基因的克隆及表达调控，2013/01-2016/12，80万元，已结题，参加
6. 国家自然科学基金面上项目，31070008，红曲菌γ-氨基丁酸代谢相关基因（gabaX）的克隆、鉴定和功能分析，2011/01-2013/12，33万元，已结题，参加
7. 国家自然科学基金青年基金项目，21002092，白蚁共生放线菌的抗菌成分研究，2011/01-2013/12，19万元，已结题，参加
期刊论文
1. Hao Ji, Ke Xu, Xiameng Dong, Da Sun, Renyi Peng, Sue Lin, Kailun Zhang, Libo Jin, Transcriptional profiling reveals molecular basis and the role of arginine in response to low-pH stress in Pichia kudriavzevii, Journal of Bioscience and Bioengineering, 2020, https://doi.org/10.1016/j.jbiosc.2020.07.014
2. Renyi Peng, Hao Ji, Libo Jin, Sue Lin, Yijiang Huang, Ke Xu, Qinsi Yang, Da Sun, Wei Wu, Macrophage-based therapies for atherosclerosis management, Journal of Immunology Research, 2020, 23(6093): 1-11（co-first author）
3. Ji H, Lu X, Zong H, Zhuge B. Functional and expression studies of two novel STL1 genes of the osmotolerant and glycerol utilization yeast Candida glycerinogenes. J Gen Appl Microbiol. 2018 Jul 23;64(3):121-126
4. Hao Ji, Xinyao Lu, Hong Zong, Bin Zhuge. γ-aminobutyric acid accumulation enhances the cell growth of Candida glycerinogenes under hyperosmotic conditions. J. Gen. Appl. Microbiol, 2018 May 21;64(2):84-89.
5. Hao Ji, Xinyao Lu, Hong Zong, Bin Zhuge(*). A synthetic hybrid promoter for D-xylonate production at low pH in the tolerant yeast Candida glycerinogenes, Bioengineered, 2017, 8(6): 700~706
6. Hao Ji, Bin Zhuge, Hong Zong, Xinyao Lu, Huiying Fang, Jian Zhuge. Role of CgHOG1 in stress responses and glycerol overproduction of Candida glycerinogenes. Current Microbiology, 2016, 73(6): 827~833
7. Hao Ji, Xinyao Lu, Chengyin Wang, Hong Zong, Huiying Fang, Jin Sun, Jian Zhuge, Bin Zhuge. Identification of a novel HOG1 homologue from an industrial glycerol producer Candida glycerinogenes. Current Microbiology, 2014, 69 (6): 909~914
8. Hao Ji, Donghua Jiang, Lilin Cao. Optimization of Fermentation parameters on T-DNA inserted Monascus purpureus mutant MT24 with high pigments production capacity. Research Journal of Biotechnology, 2012, 7(2): 9~13
9. Sue Lin, Shiwen Su, Libo Jin, Renyi Peng, Da Sun, Hao Ji, Youjian Yu, Jian Xu, Identification of microRNAs and their targets in inflorescences of an Ogura-type cytoplasmic male-sterile line and its maintainer fertile line of turnip (Brassica rapa ssp. rapifera) via high-throughput sequencing analysis, PLoS ONE, 2020, 15(7): e0236829
10. Da Sun, Jia Chen, Yuan Wang, Hao Ji, Renyi Peng, Libo Jin, Wei Wu. Advances in refunctionalization of erythrocyte-based nanomedicine for enhancing cancer-targeted drug delivery. Theranostics, 2019.9.21, 9(23): 6885-6900.
11. Meilin Zhao, Dingchang Shi, Xinyao Lu, Hong Zong, Bin Zhuge, Hao Ji. Ethanol fermentation from non-detoxified lignocellulose hydrolysate by a multi-stress tolerant yeast Candida glycerinogenes mutant. Bioresource Technology, 2019, 273:634-640.
12. Yang F, Lu X, Zong H, Ji H, Zhuge B. Gene expression profiles of Candida glycerinogenes under combined heat and high-glucose stresses. J Biosci Bioeng. 2018 Apr 30. pii: S1389-1723(18)30017-3.
13. D Jiang, H Ji, Y Ye, J Hou. Studies on screening of higher γ-aminobutyric acid-producing Monascus and optimization of fermentation. European Food Research and Technology, 2011, 232(3): 541~547
14. Jiang donghua; Liu qinying; Song yiming; Ji Hao, Antimicrobial compound from a novel Streptomyces termitum strain ATC-2 against Xanthomonas oryzae pv. Oryzae. Research journal of biotechnology, 2013.7.1, 8(7): 66~70
15. Xinyao Lu, yuqin Wang, Hong Zong, Hao Ji, Bin zhuge, Zhuoli Dong. Bioconversion of L-phenylalanine to 2-phenylethanol by the novel stress-tolerant yeast Candida glycerinogenes WL2002-5, Bioengineered, 2016, 7(6): 418~423.
16 Ji, H., Xu, K., Dong, X., Sun, D., & Jin, L. (2021). Sequential Production of D-xylonate and Ethanol from Non-Detoxified Corncob at Low-pH by Pichia kudriavzevii via a Two-Stage Fermentation Strategy. Journal of Fungi, 7(12), 1038.
17 Ji, H., Peng, R., Jin, L., Ma, J., Yang, Q., Sun, D., & Wu, W. (2021). Recent Advances in ROS-Sensitive Nano-Formulations for Atherosclerosis Applications. PHARMACEUTICS,1452.MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND.
18 Xu, Jingyu; Tang, Zonghao; He, Youwu; Cai, Shufang; Wang, Beini; Zhang, Susu; Wu, Man; Qian, Kai; Zhang, Kailun; Chai, Bo; Chen, Guorong; Xu, Ke; Ji, Hao; Xiao, Jian; Wu, Yanqing, Dl-3-n-Butylphthalide Ameliorates Diabetic Nephropathy by Ameliorating Excessive Fibrosis and Podocyte Apoptosis, Frontiers in Pharmacology, 2021, 12: 628950.
19 Jin, Libo; Zeng, Guoming; Chen, Haojie; Wang, Lei; Ji, Hao; Lin, Sue; Peng, Renyi; Sun, Da, Mechanism of Lignin Degradation via White Rot Fungi Explored Using Spectral Analysis and Gas Chromatography-Mass Spectrometry, BioResources, 2021, 16(3): 5494-5507.
20 Ye, Lu-Xia; An, Ning-Chen; Huang, Peng; Li, Duo-Hui; Zheng, Zhi-Long; Ji, Hao; Li, Hao; Chen, Da-Qing; Wu, Yan-Qing; Xiao, Jian; Xu, Ke; Li, Xiao-Kun; Zhang, Hong-Yu, Exogenous platelet-derived growth factor improves neurovascular unit recovery after spinal cord injury, Neural Regeneration Research, 2021, 16(4): 765-771.
21 Xu, Ke; Chai, Bo; Zhang, Kailun; Xiong, Jun; Zhu, Yiru; Xu, Jingyu; An, Ningchen; Xia, Weidong; Ji, Hao; Wu, Yanqing; Li, Hao; Xiao, Jian; Feng, Zhiguo; Zhang, Hongyu, Topical Application of Fibroblast Growth Factor 10-PLGA Microsphere Accelerates Wound Healing via Inhibition of ER Stress, Oxidative Medicine and Cellular Longevity, 2020, 2020: 8586314.
22 许可; 吴艳青; 嵇豪; 贾尝; 柴波; 张凯伦; 张宏宇, 用于促进伤口愈合的药物及方法, 2020-12-30, 中国, CN202011612639.7.
嵇豪; 金立波; 孙达; 彭仁义; 林苏娥; 董夏梦, 抑制库德毕赤酵母菌株细胞聚集的方法、构建和应用, 2020-06-10, 中国, CN202010522228.2.
23 陆信曜，诸葛斌，宗红，嵇豪.产甘油假丝酵母HOG途径应答研究进展[J].中国科学:生命科学,2019,49(05):585-594.
24 嵇豪; 蒋冬花; 周琴; 汪鹏荣; 董夏梦; 蔡琪敏, D001阳离子交换树脂分离红曲霉发酵液中γ-氨基丁酸的研究, 中国粮油学报, 2011,(08): 95~99
25 嵇豪; 蒋冬花; 杨叶; 周琴; 王长春, 响应面法优化超声波辅助提取红曲米中水溶性色素, 浙江师范大学学报(自然科学版), 2011, (01): 91~96
26 嵇豪，蒋冬花，叶砚，等. 红曲色素的提取工艺及其稳定性的研究[J].中国调味品, 2010, 35(7): 86-89.
发明专利：
1. 高产红曲色素紫色红曲霉Mp-41菌株及其应用, 授权发明专利，第二
2. 一种过表达产甘油假丝酵母CgGAD1提高渗透压耐受性的方法 ，发明专利，第五
3. 高产灵菌红素的粘质沙雷氏菌(Serratia marcescens)Sm-128菌株及其应用，授权发明专利，第五、
联系方式：电话：18367803306 Email：20180031@wzu.edu.cn