一 表面增强拉曼光谱（SERS）

贵金属纳米颗粒、二维贵金属纳米材料、MOFs/COFs多孔复合材料等SERS活性基底的设计、模拟和制备；

二 分析传感检测

水环境污染监控、食品安全分析、肿瘤标记物检测、病毒变异机理研究等；

三 光热-光动力治疗

光热/光动力试剂的开发，协同诱导癌细胞凋亡机理研究；

四 二维材料、金属纳米结构的等离激元光、电、磁学研究。

近年来主持的科研项目：

1. 四川省自然科学基金青年基金项目, 在研，主持。

2. 西华大学人才项目，在研，主持。

3. 国家建设高水平大学公派研究项目(已结项)。

4. 江苏省科技厅研究生科研与实践创新计划项目一项(已结项)。

近年来参与发表的学术论文：

1. Luo, X.; Tan, R.; Li, Q.; Chen, J.; Xie, Y.; Peng, J.; Zeng, M.; Jiang, M.;* Wu, C.;* He, Y.* High-sensitivity long-range surface plasmon resonance sensing assisted by gold nanoring cavity arrays and nanocavity coupling. Phys. Chem. Chem. Phys. 2023, 25, 9273–9281.

2. Luo, X.; Yue, W.; Zhang, S.; Liu, H.; Chen, Z.; Qiao, L.; Wu, C.;* Li, P.;* He, Y.* SARS-CoV-2 proteins monitored by long-range surface plasmon field-enhanced Raman scattering with hybrid bowtie nanoaperture arrays and nanocavities. Lab Chip. 2023, 23, 388−399. IF=7.52

3. Luo, X.; Zhang, S.; Xia, Z.; Tan, R.; Li, Q.; Qiao, L.; He, Y.;* Zhang, G.;* Xu, Z.* A combined surface-enhanced Raman spectroscopy (SERS)/colorimetric approach for the sensitive detection of malondialdehyde in biological samples. Anal. Chim. Acta. 2023, 1241, 340803. IF=6.91

4. He, Y.;* Liao, X.; Wu, H,; Huang, J.; Zhang, Y.; Peng, Y.; Wang, Z.; Cao, X.; Wu, C.;* Luo, X.* A controllable SERS biosensor for ultrasensitive detection of MiRNAs based on porous MOFs and subject-object recognition ability. Spectrochim. Acta, Part A. 2023, 289, 122134. IF=4.83

5. Wu, P.;* Luo, X.; Xu, Y.; Zhu, J.; Jia, W.; Fang, N.; Cai, C.* Zhu. J.-J.* Long-range SERS detection of the SARS-CoV‑2 antigen on a well-ordered gold hexagonal nanoplate film. Anal. Chem. 2022, 94, 17541−17550. IF=8.0

6. Yue, W.; Xia, Z.; Zeng, Z.; Chen, Z.; Qiao, L.; Li, P.;* He, Y.;* Luo, X.* In situ surface-enhanced Raman scattering detection of a SARS-CoV‑2 biomarker using flexible and transparent polydimethylsiloxane films with embedded Au nanoplates. ACS Appl. Nano Mater. 2022, 5, 12897−12906. IF=6.14

7. He, Y.;* Zeng, Z.; Cao, Y.; Zhang, X.; Wu, C.;* Luo, X.* Ultrasenstive SERS biosensor based on Zn²⁺ from ZnO nanoparticle assisted DNA enzyme amplification for detection of MiRNA. Anal. Chim. Acta. 2022. 1228, 340340.  IF = 6.91

8. Luo, X.;* Qiao, L.; Zhang, S.; Li, Q.; Liao, Y.; Rao, S.; Liu, H.; Zhao, Y.* S-vacancy-assisted dual-sites on NiCo₂S₄ for photoconversion of CO₂ to olefiant gas. Appl. Surf. Sci. 2022, 601, 154184(9). IF = 7.39

9. Luo, X.;* Qiao, L.; Xia, Z.; Yu. J.; Wang, X.; Huang, J.; Shu, C.; Wu, C.;* He, Y.* Shape- and size-dependent refractive index sensing and SERS performance of gold nanoplates. Langmuir 2022, 38, 6454−6463. IF = 4.33

10. Luo, X.; Zhao, X.; Gregory, W.; Marie-Helene, B.; Kevin, W.; Wu, P.;* Cai, C.* Bazuin, C. G.;* Masson, J.-F.* Multiplexed SERS detection of microcystins with aptamer-driven core-satellite assemblies. ACS Appl. Mater. Interfaces 2021, 13, 6545−6556. IF = 10.38

11. Luo, X.; Zhu, J.; Jia, W.; Fang, N.; Wu, P.;* Cai, C.;* Zhu. J.-J.* Long-range surface-enhanced Raman scattering on plasmonic nanoholes array sandwiched in symmetrical dielectric environments to boost Raman response for ultrasensitive detection of MiRNA. ACS Appl. Mater. Interfaces 2021, 13, 18301−18313. IF = 10.38

12. Luo, X.; Kang, T.; Zhu, J.; Wu, P.; * Cai, C.* Sensitivity-improved SERS detection of methyltransferase assisted by plasmonically engineered nanoholes array and hybridization-chain reaction. ACS Sens. 2020, 5, 3639−3648. IF = 9.62

13. Luo, X.;Xing, Y.; Galvan, D. D.; Zheng, E.; Wu, P.;* Cai, C.* and Yu. Q.* Plasmonic gold nanohole array for surface-enhanced Raman scattering detection of DNA methylation. ACS Sens. 2019, 4, 1534−1542. IF = 9.62

14. Luo, X.; Jiang, L.; Kang, T.; Xing, Y.; Zheng, E.;Wu, P.;* Cai, C.* and Yu. Q.* Label-Free Raman observation of TET1 protein-mediated epigenetic alterations in DNA. Anal. Chem. 2019, 91, 7304−7312. IF = 8.00

15. Luo, X.; Liu X.; Pei, Y.; Ling, Y.; Wu, P.;* Cai, C.* Leakage-free polypyrrole-Au nanostructures for combined Raman detection and photothermal cancer therapy. J. Mater. Chem. B, 2017, 5, 7949−7962. IF=7.57.