何毅，女，中共党员。2019年6月获西南大学理学博士学位，师从袁若教授，柴雅琴教授。2019年7月任西华大学理学院教师。主要研究方向为无机纳米材料与生物材料在生物传感器中的应用，旨在构建高性能的表面增强拉曼光谱生物传感器用于抗原抗体、DNA、抗生素以及环境污染物等的研究。
工作经历：
| 2019年7月-至今， 西华大学理学院 |
教育经历：
2010.09-2014.06 四川师范大学 化学专业 本科 2014.09-2019.06 西南大学 分析化学 研究生 研究方向： 主要研究方向为无机纳米材料与生物材料在生物传感器中的应用，旨在构建高性能的表面增强拉曼光谱生物传感器用于抗原抗体、DNA、抗生素以及环境污染物等的研究。 |
项目：
食品及农产品中危害残留物快速检测技术四川省青年科技创新研究团队-四川省科技计划项目专项资金
发表SCI论文：
[1] Runzi Zhang, Jia Yang, Yongguo Cao, Qianyan Zhang, Chenfeng Xie, Wanyi Xiong, Xiaojun Luo*, Yi He*. Efficient 2D MOFs nanozyme combining with magnetic SERS substrate for ultrasensitive detection of Hg2+. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 312, 2024, 124062.
[2] Runzi Zhang, Qianyan Zhang, Ying Gao, Jia Yang, Xue Zeng, Minghang Jiang, Mengjun Wang, Xiaojun Luo*, Yi He*. DNAzyme amplifaction strategy coupled with peanut-shaped FexOy @MMC@Au and COF@Au synergistic SERS enhancement for ultrasensitive analysis of chloramphenicol. Sensors and Actuators: B. Chemical, 401, 2024, 134962.
[3] Runzi Zhang, Qianyan Zhang, Jia Yang, Shuping Yu, Xiao Yang*, Xiaojun Luo*, Yi He*. Ultrasensitive detection strategy for CAP by molecularity imprinted SERS sensor based on multiple synergistic enhancement of SiO2@AuAg with MOFs@Au signal carrier. Food Chemistry, 445, 2024, 138717.
[4] Yi He*, Chenfeng Xie, Qianyan Zhang, Rui Cheng, Xiyu Liu, Yunli Guo, Chunhong Liu, Minghang Jiang, Mengjun Wang*, Xiaojun Luo*. SERS Immunoassay Based on an Enzyme-Catalyzed Cascade Reaction and Metal–Organic Framework/Alkaline Phosphatase for Ultrasensitive Detection of Adenosine Triphosphate. ACS Applied Materials & Interfaces, 16, 2024, 1712–1718.
[5] Jia Yang, Runzi Zhang, Jiaxian Liu, Renbo Xiong, Yi He*, Xiaojun Luo*, Xiao Yang*. Well-ordered Au@Ag NBPs/SiO2 nanoarray for sensitive detection of chloramphenicol via DNAzyme-assisted SERS sensing. Food Chemistry, 454, 2024, 139806.
[6] Runzi Zhang, Shunbi Xie*, Xiang He, Ying Gao, Mengjun Wang, Minghang Jiang, Xiaojun Luo, Yi He*. Ultrasensitive Detection of Chloramphenicol in Milk Using a “Y-Shaped” SERS Biosensor Based on Magnetic Plasmonic Nanostructures and EXPAR Technology. ACS Applied Nano Materials, 7, 2024, 24172−24180.
[7] Runzi Zhang, Shunbi Xie*, Qianyan Zhang, Ying Gao, Xiang He, Shanshan Jin, Junhao Leng, lian Zhang, Yi He*. "Explosive" CaCO3 microcapsules driven by EDTA combined with a "signal booster" semiconductor Zn0.995Ce0.005O SERS substrate for ultra-sensitive SERS detection of chloramphenicol. Analytica Chimica Acta, 1331, 2024, 343308.
[8] Runzi Zhang, Shunbi Xie*, Hongcheng Zhang, Jia Yang, Minghang Jiang*, Lian Zhang, Yi He*. A dual-mode colorimetric and surface-enhanced Raman strategy for chloramphenicol detection based on the Au@Pt nanozyme and EXPAR. Microchemical Journal, 207, 2024, 111990.
[9] Zhiyou Zeng, Xiaoyu Yang, Yongguo Cao, Sanshan Pu, Xinyu Zhou, Rongli Gu, Yiqian Zhang, Caijun Wu, Xiaojun Luo and Yi He*. High-efficiency SERS platform based on 3D porous PPDA@Au NPs as a substrate for the detection of pesticides on vegetables. Analytical Methods, 37, 2023, 9.
[10] Yi He*, Zhiyou Zeng, Yongguo Cao, Xiao Zhang, Caijun Wu*, Xiaojun Luo*. Ultrasensitive SERS biosensor based on Zn2+ from ZnO nanoparticle assisted DNA enzyme amplification for detection of miRNA. Analytica Chimica Acta, 1228, 2022, 0340.
[11] Yi He*，Zhiyou Zeng, Yongguo Cao, Xiao Zhang, Caijun Wu*, Xiaojun Luo*. Ultrasensitive SERS biosensor based on Zn2+ from ZnO nanoparticle assisted DNA enzyme amplification for detection of miRNA. Analytica Chimica Acta, 1228(2022)340340.
[12] Xiaojun Luo*, Weiling Yue, Shutong Zhang, Haopeng LIu, Zhinan Chen, Ling Qiao, Caijun Wu, Panjie Li*, Yi He*. SERS-CoV-2 proteins monitored by long-range surface plasmon field-enhanced Raman scattering with hybrid bowtie nanoaperture arrays and nanovavities. Lab on a Chip. 2023,23,388-399.
[13] Xiaojun Luo, Shutong Zhang, Zhichao Xia, Rui Tan, Qiuju Li, Ling Qiao, Yi He*, Guoqi Zhang*, Zhihong Xu*. Analytica Chimica Acta, 1241 (2023) 340803.
[14] Yi He*, Xiangjian Liao, Haonan Wu, Jialiang Huang, Yi Zhang, Yanyu Peng, Zhen Wang, Xin cao, Caijun Wu*, Xiaojun Luo*. A controllable SERS biosensor for ultrasensitive detection of miRNAs based on porous MOFs and subject-object recognition ability. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 289, 2023, 122134.
[15] Weiling Yue, Zhichao Xia, Zhiyou Zeng, Zhinan Chen, Ling Qiao, Panjie Li*, Yi He*, Xiaojun Luo*. In situ Surface-Enhanced Raman Scattering Detection of a SARS-CoV-2 Biomarker Using Flexible and Transparent Polydimethylsiloxane Films with Embedded Au Nanoplates. ACS Applied Nano Materials, 2022, 5, 12897-12906.
[16] Xiaojun Luo*, Ling Qiao, Zhichao Xia, Jiaming Yu, Xiaozhou, Wang, Juhong Huang, Chang Shu, Caijun Wu*, Yi He*. Shape- and Size-Dependent Refractive Index Sensing and SERS Performance of Gold Nanoplates. Langmuir, 2022, 38, 6454-6463.
[17] Minghang Jiang*, Mengfei Zhu, Mengjun Wang, Yi He, Xiaojun Luo, Caijun Wu; Liyun Zhang, Zhong Jin,* Review on Electrocatalytic Coreduction of Carbon Dioxide and Nitrogenous Species for Urea Synthesis, ACS Nano, 2023, 17, 3209-3224.
[18] Xiaojun Luo, Rui Tan, Qiuju Li, Jiaxin Chen, Yalin Xie, Jiayi Peng, Mei Zeng, Minghang Jiang*, Caijun Wu*, Yi He*. High-sensitivity long-range surface plasmon resonance sensing assisted by gold nanoring cavity arrays and nanocavity coupling. Phys. Chem. Chem. Phys. 2023.
[19] Yi He, Xia Yang, Ruo Yuan, and Yaqin Chai, “Off” to “On” Surface-Enhanced Raman Spectroscopy Platform with Padlock Probe-Based Exponential Rolling Circle Amplification for Ultrasensitive Detection of MicroRNA 155. Anal. Chem. 2017, 89, 2866−2872.
[20] Yi He, Xia Yang, Ruo Yuan, and Yaqin Chai, Switchable Target-Responsive 3D DNA Hydrogels as a Signal Amplification Strategy Combining with SERS Technique for Ultrasensitive Detection of miRNA 155. Anal. Chem. 2017, 89, 8538−8544.
[21] Yi He, Yue Wang, Xia Yang, Shunbi Xie, Ruo Yuan, and Yaqin Chai, Metal Organic Frameworks Combining CoFe2O4 Magnetic Nanoparticles as Highly Efficient SERS Sensing Platform for Ultrasensitive Detection of N‑Terminal Pro-Brain Natriuretic Peptide. ACS Appl. Mater. Interfaces 2016, 8, 7683−7690.
[22] Yi He, Shunbi Xie, Xia Yang, Ruo Yuan, and Yaqin Chai, Electrochemical Peptide Biosensor Based on in Situ Silver Deposition for Detection of Prostate Specific Antigen. ACS Appl. Mater. Interfaces 2015, 7, 13360−13366.
[23] Yi He, Xia Yang, Ruo Yuan, and Yaqin Chai, A novel ratiometric SERS biosensor with one Raman probe for ultrasensitive microRNA detection based on DNA hydrogel amplification. J. Meter. Chem. B 2019, 7, 2643--2647.