近日，课题组研究成果 “Ruthenium-catalyzed acceptorless dehydroge.native coupling of o-aminobenzyl alcohols with ketones to quinolines in the presence of carbonate salt" 发表在 J. Catal. 2021, 395, 340-349

A ruthenium complex bearing a functional 2,20-bibenzimidazole ligand [(p-cymene)Ru(BiBzImH2)Cl][Cl] was designed, synthesized and found to be a general and highly efficient catalyst for the synthesis of quinolines via acceptorless dehydrogenative coupling of o-aminobenzyl alcohols with ketones in the presence of carbonate salt. It was confirmed that NH units in the ligand are crucial for catalytic activity. The application of this catalytic system for the scale-gram synthesis of biologically active molecular was also undertaken. Notably, this research exhibits new potential of metal–ligand bifuctional catalysts for acceptorless dehydrogenative reactions.

该论文网址：

https://www.sciencedirect.com/science/article/pii/S002195172030508X

课题组另一项研究成果 “N‑Methylation of Amines with Methanol in the Presence of Carbonate Salt Catalyzed by a Metal−Ligand Bifunctional Ruthenium Catalyst [(p‑cymene)Ru(2,2′-bpyO)(H2O)]” 发表在   J. Org. Chem. 2021, 86, 2621−2631。

A ruthenium complex [(p-cymene)Ru(2,2′-bpyO)(H2O)] was found to be a general and efficient catalyst for the Nmethylation of amines with methanol in the presence of carbonate salt. Moreover, a series of sensitive substituents, such as nitro, ester, cyano, and vinyl groups, were tolerated under present conditions. It was confirmed that OH units in the ligand are crucial for the catalytic activity. Notably, this research exhibited the potential of metal−ligand bifunctional ruthenium catalysts for the hydrogen
autotransfer process.

该论文网址：

https://pubs.acs.org/doi/10.1021/acs.joc.0c02685