简介:

   杨继榕，博士，中国科学院深圳先进技术研究院副研究员，中国科学院特别研究助理。长期致力于骨/软骨组织修复再生的研究，并聚焦微环境调控干细胞分化和生物3D打印技术应用。先后主持国家自然科学基金青年基金、中国博士后基金面上项目、中国科学院特别研究助理项目、广东省基础与应用基础研究基金项目、以及深圳市项目；参与科技部重点研发计划和深圳市基础研究重点项目。迄今为止，以第一作者或通讯在Nature Communications、Biomaterials、Bone Research、Acta Biomaterialia、Composites Part B: Engineering等期刊发表相关论文10篇，累计发表论文20余篇。申请国家发明专利9项，授权发明专利3项。中国生物材料学会生物材料先进制造分会委员，中国医药生物技术学会3D打印分会委员，担任Biomaterials Translational 期刊青年编委。

研究方向:

骨/软骨修复与再生；生物3D打印；水凝胶；基质微环境调控。

主要学术任职:

中国科学院特别研究助理

学科类别：

生物医学工程；生物材料

主要代表论著:

(1) Tao Song; Fengxin Zhao; Ling Yan; Puxin Liu; Jirong Yang**; Changshun Ruan; Dongxiao Li; Yumei Xiao*; Xingdong Zhang; Structure driven bio-responsive ability of injectable nanocomposite hydrogels for efficient bone regeneration, Biomaterials, 2024, 309:122601.

(2) Jirong Yang, Zhigang Chen, Chongjian Gao, Juan Liu, Kaizheng Liu, Xiao Wang, Xiaoling Pan, Guocheng Wang, Hongxun Sang, Haobo Pan, Wenguang Liu, Changshun Ruan*. A mechanical-assisted post-bioprinting strategy for challenging bone defects repair, Nature Communications 2024, 15(1): 3565.

(3) Jirong Yang; Huimin He; Duo Li; Qian Zhang; Lizhi Xu; Changshun Ruan*; Advanced Strategies in the Application of Gelatin-based Bioink for Extrusion Bioprinting, Bio-Design and Manufacturing, in press.

(4) Tao Song#; Jirong Yang#; Puxin Liu; Minjun Liu; Dongxiao Li; Yumei Xiao*;

Yan Wang*, Xingdong Zhang; Icariin self-crosslinked network functionalized strontium-doped bioceramic scaffolds synergistically enhanced the healing of osteoporotic bone defects, Composites Part B: Engineering, 2022, 235:109759.

(5) Jirong Yang; Zizhao Tang; Yifan Liu; Zhaocong Luo; Yumei Xiao*; Xingdong Zhang; Comparison of chondro-inductivity between collagen and hyaluronic acid hydrogel based on chemical/physical microenvironment, International Journal of Biological Macromolecules, 2021, 182:1941–1952.

(6) Jirong Yang#; Yumei Xiao#; Zizhao Tang; Zhaocong Luo; Dongxiao Li; Qiguang Wang*; Xingdong Zhang; The negatively charged microenvironment of collagen hydrogels regulates the chondrogenic differentiation of bone marrow mesenchymal stem cells in vitro and in vivo, Journal of Materials Chemistry B, 2020, 8:4680-4693.

(7) Yanbo Liu#; Jirong Yang#; Zhaocong Luo; Dongxiao Li; Jian Lu; Qiguang Wang; Yumei Xiao*; Xingdong Zhang; Development of an injectable thiolated icariin functionalized collagen/hyaluronic hydrogel to promote cartilage formation in vitro and in vivo, Journal of Materials Chemistry B, 2019, 7:2845-2854.

(8) Jirong Yang; Yuanqi Li; Yanbo Liu; Dongxiao Li; Lei Zhang; Qiguang Wang*; Yumei Xiao*; Xingdong Zhang; Influence of hydrogel network microstructures on mesenchymal stem cells chondrogenesis in vitro and in vivo, Acta Biomaterialia, 2019, 91: 159-172.

(9) Jirong Yang; Yanbo Liu; Long He; Qiguang Wang; Lan Wang; Tun Yuan*; Yumei Xiao*; Yujiang Fan; Xingdong Zhang; Icariin conjugated hyaluronicacid/collagen hydrogel for osteochondral interface restoration, Acta Biomaterialia, 2018, 74: 156-167.