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李昌华 教授 博士生导师    

    

学习和工作经历:

    南开大学药物化学生物学国家重点实验室研究员、药学院教授。国家优青基金获得者,天津市高层次引进人才,南开大学百名青年学科带头人。2007年获中国科技大学学士学位,2012年获中国科技大学博士学位(导师:刘世勇教授),读博期间在德国美因茨大学学习一年(导师:Manfred Schmidt教授),2012-2015年在日本东京大学和RIKEN从事博士后研究(合作导师:Takuzo AIDA教授),2015年回南开大学组建独立课题组。

科研成果:

    迄今已在JACS (2篇,独立通讯), Angew. Chem. Int. Ed. (3篇,1篇独立通讯&2篇一作), Adv. Mater., Adv. Func. Mater, ACS Nano, Small, Anal. Chem., Macromolecules等国际知名学术期刊上发表30余篇SCI论文,共计申请11项国家发明专利。研究工作已开始受到国内外同行专家的认可和关注,已发表的论文共被SCI引用1800余次,H因子22,1篇论文入选ESI Highly Cited Papers (As of March 2013), 2篇论文被选为JACS Spotlight、ACS Noteworthy Chemistry研究亮点专栏重点报道。曾荣获天津市青年科技创新人才奖、安徽省科学技术奖一等奖、 中国科学院院长特别奖、中国科学院优秀博士学位论文奖、教育部学术新人奖、求是研究生奖等学术奖励。

近期代表作:

  • M. H. Su,# Q. J. Han,# X. S. Yan, Y. N. Liu, P. Luo, W. H. Zhai, Q. Z. Zhang*, L. Y. Li, C. H. Li* “A Supramolecular Strategy to Engineering a Non-photobleaching and Near-Infrared Absorbing Nano-J-Aggregate for Efficient Photothermal Therapy”
    ACS Nano 2021, 15, 5032-5042. (# These authors contributed equally)
  • X. S. Yan,# M. H. Su,# Y. N. Liu, Y. K. Zhang, H. Zhang, C. H. Li* “Molecularly Engineered Hierarchical Nanodisc from Antiparallel J−stacked BODIPY Conjugates: Application to Theranostics with Mutually Beneficial Properties”
    Adv. Funct. Mater. 2021, 31, 2008406. (# These authors contributed equally)
  • M. H. Su, S. X. Li, H. Zhang, J. Q. Zhang, H. L. Chen, C. H. Li* “Nano-Assemblies from J-Aggregated Dyes: A Stimuli-Responsive Tool Applicable to Living Systems”
    J. Am. Chem. Soc. 2019141, 402-413.
  • W. H. Zhai, Y. K. Zhang, M. Liu, H. Zhang, J. Q. Zhang, C. H. Li* “Universal Scaffold for an Activatable Photosensitizer with Completely Inhibited Photosensitivity”
    Angew. Chem. Int. Ed. 201958, 16601-16609. (Selected as Hot Paper) (Highlighted by SYNFACTS)
  • H. L. Chen, X. J. He, M. H. Su, W. H. Zhai, H. Zhang, C. H. Li* “A General Strategy Toward Highly Fluorogenic Bioprobes Emitting across the Visible Spectrum”
    J. Am. Chem. Soc. 2017139, 10157-10163. (Highlighted by JACS Spotlights)
  • C. H. Li, T. Wu, C. Y. Hong, G. Q. Zhang*, S. Y. Liu* “A General Strategy to Construct Fluorogenic Probes from Charge-Generation Polymers (CGPs) and AIE-Active Fluorogens via Triggered Complexation” 
    Angew. Chem. Int. Ed. 201251, 455-459. (Highlighted by ACS Noteworthy Chemistry; ESI Highly Cited Papers)
  • C. H. Li, Y. X. Zhang, J. M. Hu, J. J. Cheng*, S. Y. Liu* “Reversible Three-State Switching of Multicolor Fluorescence Emission by Multiple Stimuli Modulated FRET Processes within Thermoresponsive Polymeric Micelles” 
    Angew. Chem. Int. Ed. 201049, 5120-5124.

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