一、研究方向

①人工智能算法驱动的虚拟药物筛选及药物作用机制

②系统药理学驱动多模态中药复方成分优化

二、研究成果

①Li Yi, Wang Kexin, Chen Yupeng, Cai Jieqi, Qin Xuemei, Lu Aiping, et al. A System Pharmacology Model for Decoding the Synergistic Mechanisms of Compound Kushen Injection in Treating Breast Cancer. Front. Pharmacol. 12:723147. doi: 10.3389/fphar.2021.723147（第一作者，Frontiers in Pharmacology，中科院2区，IF=5.81）；

②Wu Qi, Yin Chuanhui, Li Yi, Cai Jieqi, Yang Hanyun, Huang Yingying, et al. Detecting Critical Functional Ingredients Group and Mechanism of Xuebijing Injection in Treating Sepsis. Front. Pharmacol. 12:769190. doi: 10.3389/fphar.2021.769190（共同共一作者，3/3，Frontiers in Pharmacology，中科院2区，IF=5.81）;

③Wu Jie, Wang Kexin, Liu Qinwen, Li Yi, Huang Yingying, Liu Yujie , et al. An Integrative Pharmacology Model for Decoding the Underlying Therapeutic Mechanisms of Ermiao Powder for Rheumatoid Arthritis. Front. Pharmacol. 13:801350. doi: 10.3389/fphar.2022.801350（共同第一作者，3/3， Frontiers in Pharmacology，中科院2区，IF=5.81 ）；

④Liu Yujie, Liu Qinwen, Yin Chuanhui, Li Yi, Wu Jie, Chen Quanlin, et al. Uncovering Hidden Mechanisms of Different Prescriptions Treatment for Osteoporosis via Novel Bioinformatics Model and Experiment Validation. Front. Cell Dev. Biol. 10:831894. doi: 10.3389/fcell.2022.831894（共同作者，4/9，Frontiers in Cell and Developmental Biology，中科院2区，IF=6.684）;

⑤Wang Kexin, Li Kai, Chen Yupeng, Wei Genxia, Yu Hailang, Li Yi, et al. Computational Network Pharmacology–Based Strategy to Capture Key Functional Components and Decode the Mechanism of Chai-Hu-Shu-Gan-San in Treating Depression. Front. Pharmacol. 12:782060. doi: 10.3389/fphar.2021.782060（共同作者，6/12， Frontiers in Pharmacology，中科院2区，IF=5.81）；

⑥Chen Yupeng, Wang Kexin, Cai Jieqi, Yi Li, Yu Hailang, Wu Qi, et al. Detecting key functional components group and speculating the potential mechanism of Xiao-Xu-Ming decoction in treating stroke（共同作者，4/13， Frontiers in Cell and Developmental Biology，中科院2区，IF=6.684 ）