程娘梅:理学硕士,福建医科大学孟超肝胆医院研究实习员,曾参与福建省科技重大专项项目、肿瘤免疫治疗抗体工程技术研究中心、福建省自然基金等项目,近五年内在相关领域发表多篇SCI论文和专利。
主持或参与项目:
1、福建医科大学,启航基金项目,2019QH1298,转录组学分析片仔癀抑制肝癌细胞侵袭、迁移的分子机制与验证,2020-04至2023-04,5万元,已结题,主持
2、福建省卫生健康委,青年科研项目,2020QNA072,Lnc-CCNH-8调控肝癌细胞PD-L1表达的机制研究, 2021-01至2023-12,5万元,已结题, 主持
3、福州市科技局,医疗项目,2021-S-100,CircBARD1调控肝癌侵袭/迁移的分子机制研究,2021-06至2023.06,6万元,已结题,主持。
4、福建省科学技术厅, 自然科学基金项目, 2023J011467, 环状RNA circ_0058051调控肝癌转移的分子机制研究, 2023-08 至 2026-08, 10万元, 在研, 主持
代表论文和专利:
(1)Ling Li #, Niangmei Cheng#, Xinhui Huang #, Xiadi Weng , Yubin Jiao , Jingfeng Liu, Wuhua Guo. Efficacy and safety of endovascular brachytherapy combined with transarterial chemoembolization for the treatment of hepatocellular carcinoma patients with type III or IV portal vein tumor thrombosis. World J Surg Oncol. 2022; 20: 30.
(2)Yingchao Wang #, Yue Zhong #, Xiaoyuan Zheng#, Niangmei Cheng #, Yong Yang, Ye Yang , Fei Wang, Qiuyu Zhuang, Yao Huang, Wuhua Guo, Naishun Liao, Xiaoyu Yang , Bixing Zhao, Xiaolong Liu. LncRNA TIALD contributes to hepatocellular carcinoma metastasis via inducing AURKA lysosomal degradation. Cell Death Discov. 2023 Aug 26;9(1):316.
(3)Song You#, Niangmei Cheng #, Fei Wang, Xiaoyuan Zheng, Yingchao Wang, Bixing Zhao,* and Jingfeng Liu. Hsa_circ_0001687 Function as a ceRNA to Facilitate Hepatocellular Carcinoma Progression via miR-140- 3p/FOXQ1 Axis. Protein & Peptide Letters,2023.9. 1-11.
(4)Jiahui Xiong#, Yongping Lai #, Niangmei Cheng #, Jizhe Liu#, Fei Wang , Xiaoyuan Zheng , Yingchao Wang, Qiuyu Zhuang , Yantin Lin, Jingfeng Liu , Yixuan Yang , Bixing Zhao *, Xiaoyu Yang **. Lnc-PLA2G4A-4 facilitates the progression of hepatocellular carcinoma by inducing versican expression via sponging miR-23b-3p. Heliyon. 2023 Jul 26;9(8):e18698.
(5)Wang Jianhua#, *; Cheng Niangmei#; Yang Qiu; Zhang Zhihua; Zhang Qiqing*. Double-Layered Collagen/Silk Fibroin Composite Scaffold that Incorporates TGF-beta 1 Nanoparticles for Cartilage Tissue Engineering. Journal of Biomaterials and Tissue Engineering, 2015, 5: 357-363.
(6) Jianhua Wang; Qiu Yang; Niangmei Cheng; Xiaojun Tao; Zhihua Zhang; Xiaomin Sun; Qiqing Zhang*; Collagen/silk fibroin composite scaffold incorporated with PLGA microsphere for cartilage repair, Materials Science and Engineering C, 2016, 61: 705-711.
授权发明专利
(1) 张其清; 王建华; 程娘梅; 杨秋; 张志华; 负载生长因子的丝素蛋白/胶原蛋白支架材料及制备方法, 2017-01-25, 中国, ZL201510062718.8
(2) 张其清; 王建华; 程娘梅; 杨秋; 张志华; 负载BMP丝素蛋白/胶原蛋白支架材料及其制备方法, 2017-01-25, 中国, ZL201510062801.5