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刘聪 博士、副教授、硕士生导师     进组时间: 2018.07

刘聪,博士

职 称:副教授

研究方向:微生物学

邮 箱:liucong0426@126.com

联系方式:江苏省徐州市,江苏师范大学生科院4号楼105

教育经历:

2014.09-2018.06:中国农业大学,生物学院微生物系,博士研究生,获理学博士学位

2007.09-2010.07:中国农业大学,生物学院微生物系,硕士研究生,获理学硕士学位

2002.09-2006.07:东北农业大学,生命科学学院生物工程系,本科,获学士学位

工作经历:

2022.07-至今:江苏师范大学,生命科学学院,副教授

2018.06-2022.06:江苏师范大学,生命科学学院,讲师

2013.12-2014.08:新加坡南洋理工大学,环境工程研究中心,访问学者

2013.09-2014.06:江苏师范大学,江苏省药用植物生物技术重点实验室,助理实验师

2010.08-2013.06:国药集团北京生物制品研究所有限责任公司,质保部,助理工程师

主要工作业绩:

2019年入选江苏省“双创计划”科技副总;2019年获徐州市发明协会科技创新三等奖;获得江苏师范大学第十届青年教师教学优胜奖三等奖;目前共承担本科生课程6门;主持国家自然科学青年项目1项、江苏师范大学自然科学研究基金1项;以第一或通讯作者共发表SCI论文20篇;并发表教改论文1篇。

执教课程:

基因工程;生物化学;分子生物学实验;微生物学实验;高级微生物学;外文文献导读;

研究方向:

细菌生物被膜分子机制和生物制药:主要从事微生物形成生物被膜的分子机制研究,主要研究对象为Shewanella putrefaciencs CN32菌株,该菌株具有较强的金属还原能力,在微生物发电、环境修复中有重要作用,同时也是海水鱼腐败菌和条件致病菌。该菌能形成生物被膜,生物被膜的形成在其环境修复过程中有重要的作用,因此其研究具有重要意义。除此之外,还对粘质沙雷氏菌合成生物农药灵菌红素的代谢调控进行基础研究。

承担项目:

1.    国家自然科学基金面上项目:第二信使cAMPc-di-GMP响应碳源信号交叉调控腐败希瓦氏菌生物被膜起始吸附的分子机制(32370583),项目主持人;项目来源:国家基金委;期限:2024.01-2027.12;经费:50万元

2.    国家自然科学基金青年科学基金项目:转录因子SlyA调控腐败希瓦氏菌生物被膜形成的分子机制研究(31900401),项目主持人;项目来源:国家基金委;期限:2020.01-2022.12;经费:24万元

3.    江苏省自然科学基金面上项目:β-内酰胺类抗生素诱导腐败希瓦氏菌形成生物被膜的分子机制;项目主持人;项目来源:江苏省科技厅;期限:2023.07-2026.06;经费:10万元

4.    江苏师范大学自然科学研究基金项目:腐败希瓦氏菌形成生物被膜的关键功能基因鉴定(18XLRX034);项目主持人;项目来源:江苏师范大学;期限:2019.01-2020.12;经费:30万元

代表性论文:

1.      Cong Liu#, Di Sun#, Jiawen Liu, Ying Chen, Xuge Zhou, Yunrui Ru, Jingrong Zhu, Weijie Liu*. cAMP and c-di-GMP synergistically support biofilm maintenance through the direct interaction of their effectors. Nature communications, 2022, 13, 1493.

第一作者,SCI一区,自然指数期刊,IF17.694,独立完成单位,亮点文章

2.      Jiawen Liu, Jingrong Zhu, Qian Xu, Rui Shi, Cong Liu*, Di Sun*, Weijie Liu*. Functional identification of two novel carbohydrate-binding modules of glucuronoxylanase CrXyl30 and their contribution to the lignocellulose saccharification. Biotechnology for Biofuels and Bioproducts, 2023,16:40. 通讯作者,SCI一区,A4IF7.67

3.      Jiawen Liu, Qian Xu, Yan Wu, Di Sun, Cong Liu, Jingrong Zhu, Cong Liu*, Weijie Liu*. Potentiating the chitinolytic system of Serratia marcescens BWL1001 by carbohydrate-binding modules of ChiB and ChiC. Enzyme and Microbial Technology, 2022.

通讯作者,SCI三区,IF: 3.705

4.      Weijie Liu #, Zhen Dong#, Di Sun, Ying Chen, Shiwei Wang, Jingrong Zhu, Cong Liu*. Bioconversion of kitchen wastes into bioflocculant and its pilot-scale application in treating iron mineral processing wastewater. Bioresource Technology, 2019, 288:121505.

通讯作者,SCI一区,IF11.889

5.      Cong Liu#, Yan Hao#, Jihong Jiang, Weijie Liu*. Valorization of untreated rice bran towards bioflocculant using a lignocellulose-degrading strain and its use in microalgal biomass harvest. Biotechnology for Biofuels, 2017, 10(1): 90.      第一作者,SCI一区,IF7.67

6.      Weijie Liu*, Chenchu Zhao, Jihong Jiang, Qian Lu, Yan Hao, Liang Wang, Cong Liu*. Bioflocculant production from untreated corn stover using Cellulosimicrobium cellulans L804 isolate and its application to harvesting microalgae. Biotechnology for Biofuels, 2015, 8(1):1-12.                                                                                                                                                              通讯作者,SCI一区,IF7.67

7.      Cong Liu, Jinshui Yang, Liang Liu, Baozhen Li, Hongli Yuan*, Weijie Liu*. Sodium lactate negatively regulates Shewanella putrefaciens CN32 biofilm formation via a three-component regulatory system (LrbS-LrbA-LrbR). Applied and Environmental Microbiology, 201783(14), e00712-17.                                                           美国微生物学会期刊,第一作者,SCI二区TopIF5.005

8.      Di Sun#, Weijie Liu#, Xuge Zhou, Yunrui Ru, Jiawen Liu, Jingrong Zhu, Cong Liu*. Organic hydroperoxide induces prodigiosin biosynthesis in an OhrR-dependent manner in Serratia sp. ATCC 39006. Applied and Environmental Microbiology, 2022, 88, e02041-21.

 通讯作者,美国微生物学会期刊,SCI二区TopIF5.005

9.      Weijie Liu, Zhen Dong, Di Sun, Qinxin Dong, Shiwei Wang, Jingrong Zhu, Cong Liu*. Production of bioflocculant using feather waste as nitrogen source and its use in recycling of straw ash-washing wastewater with low-density and high pH property. Chemosphere, 2020, 252, 126495.                                                                                                                                                     通讯作者,SCI二区TOPIF8.943

10.   Cong Liu, Yanting You, Ruofei Zhao, Di Sun, Peng Zhang, Jihong Jiang, Aihua Zhu, Weijie Liu*. Biosurfactant production from Pseudomonas taiwanensis L1011 and its application in accelerating the chemical and biological decolorization of azo dyes. Ecotoxicology and Environmental Safety, 2017, 145: 8-15.                                                                                                  第一作者,SCI二区,IF7.129

11.   Weijie Liu#,*, Cong Liu#, Liang Liu, Yanting You, Jihong Jiang, Zhengkun Zhou, Zhen Dong. Simultaneous decolorization of sulfonated azo dyes and reduction of hexavalent chromium under high salt condition by a newly isolated salt-tolerant strain Bacillus circulans BWL1061. Ecotoxicology and Environmental Safety, 2017,141:9-16.

共同第一作者,SCI二区,IF7.129

12.   Cong Liu, Di Sun, Jingrong Zhu, Weijie Liu*. Two-component signal transduction systems: a major strategy for connecting input stimuli to biofilm formation. Frontiers in Microbiology, 2019, 9, 3279                                                             第一作者,SCI二区TopIF6.064

13.   Weijie Liu#, Ying Chen#, Xuge Zhou, Jiawen Liu, Jingrong Zhu, Shiwei Wang, Cong Liu*, Di Sun*. The cyclic AMP receptor protein, Crp, is required for the decolorization of acid yellow 36 in Shewanella putrefaciens CN32. Frontiers in Microbiology, 2020, 11, 596372.

通讯作者,SCI二区TopIF6.064

14.   Cong Liu, Di Sun, Jingrong Zhu, Jiawen Liu and Weijie Liu*. The Regulation of Bacterial Biofilm Formation by cAMP-CRP: A Mini-Review. Frontiers in Microbiology, 2020, 11, 802.                                                                                    第一作者,SCI二区TopIF6.064

15.   Weijie Liu, Yanting You, Di Sun, Shiwei Wang, Jingrong Zhu, Cong Liu*. Decolorization and detoxification of water-insoluble Sudan dye by Shewanella putrefaciens CN32 co-cultured with Bacillus circulans BWL1061. Ecotoxicology and Environmental Safety, 2018,166:11-17.                                                                                                                                              通讯作者,SCI二区,IF6.129

16.   Cong Liu, Di Sun, Jiawen Liu, Jingrong Zhu, Weijie Liu*. Recent advances and perspectives in efforts to reduce the production and application cost of microbial flocculants. Bioresources and Bioprocessing, 2021, 8, 51.            第一作者,SCI二区,IF4.983

17.   Jiawen Liu#, Di Sun#, Jingrong Zhu, Cong Liu*, Weijie Liu*. Carbohydrate-binding modules targeting branched polysaccharides: Overcoming side-chain recalcitrance in a non-catalytic approach. Bioresources and Bioprocessing, 2021, 8, 28.

通讯作者,SCI二区,IF4.983

18.   Weijie Liu, Jing Yang, Yanning Tian, Xuge Zhou, Shiwei Wang, Jingrong Zhu, Di Sun*, Cong Liu*. An in situ extractive fermentation strategy for enhancing prodigiosin production from Serratia marcescens BWL1001 and its application to inhibiting the growth of Microcystis aeruginosa. Biochemical Engineering Journal, 2021, 166, 107836.                                                                通讯作者,SCI二区,IF4.446

19.   Cong Liu, Ke Wang, Jihong Jiang, Weijie Liu*, Jingyuan Wang. A novel bioflocculant produced by a slat-tolerant, alkaliphilic and biofilm-forming strain Bacillus agaradhaerens C9 and its application in harvesting Chlorella minutissima UTEX2341. Biochemical Engineering Journal. 2015, 93: 166-172.                                                                                                           第一作者,SCI二区,IF: 4.446

20.   Jiawen Liu#, Cong Liu#, Shilei Qiao, Zhen Dong, Di Sun, Jingrong Zhu, Weijie Liu*. One-step fermentation for producing xylo-oligosaccharides from wheat bran by recombinant Escherichia coli containing an alkaline xylanase. BMC Biotechnology, 2022, 22, 6.

共同第一作者,SCI三区,IF3.329

21.   Yunrui Ru#, Jiawen Liu#, Peijing Xu, Wenhui Gao, Di Sun, Jingrong Zhu, Cong Liu*, Weijie Liu*. Application of the biosurfactant produced by Bacillus velezensis MMB-51 as an efficient synergist of sweet potato foliar fertilizer. Journal of Surfactants and Detergents, 2022.                                                                                                                                                                   通讯作者,SCI四区,IF1.972

教改论文:

1.     刘聪,孙地,朱静榕,蒋虹,刘伟杰*。基因工程教学改革的分析与思考。教育现代化,20204月第32期。

主要获奖:

1.      江苏省高等学校科学技术研究成果三等奖(厅级,第二完成人)

2.      2021第四届全国大学生生命科学竞赛三等奖(国家级,第二指导教师)2020

3.      第四届全国大学生生命科学创新创业大赛指导教师三等奖(国家级,第一指导教师)2019

4.      江苏省“双创计划”科技副总(省部级,2019

5.      徐州市发明协会科技创新三等奖(徐州市发明协会,2018

6.      江苏师范大学第十届青年教师教学优胜奖三等奖