姜立波 男,博士,教授,博士生导师
办公室:山东理工大学13号教学楼E22
电子邮箱:libojiang@sdut.edu.cn
青年泰山学者、教授,2019年入选山东省泰山学者“青年专家”。2016年博士毕业于北京林业大学并留校任教,2021年任职于山东理工大学生命与医药学院。在国际国内重要学术期刊发表论文50余篇,其中第一/共同第一作者/通讯作者25篇;参编专著章节2篇;授权发明专利4项。主持国家自然科学基金项目2项,参与国家自然科学基金面上,国际交流合作等项目多项。
研究方向:
统计遗传学与生物信息学,针对复杂性状基因解析这一当前生物学理论研究所面临的最主要难题之一,发展统计与计算的方法探究复杂性状的遗传机制。研究成果先后获得教育部高等学校科学研究优秀成果奖二等奖和北京市科学技术奖三等奖。
学习、工作经历
2005.09-2009.06, 山东农业大学, 林学院, 本科/学士
2009.09-2012.06, 甘肃农业大学, 草业学院, 研究生/硕士(导师: 沈慧敏)
2012.09-2016.12, 北京林业大学, 生物科学与技术学院, 研究生/博士(导师: 邬荣领)
2016.12-2021.9, 北京林业大学, 生物科学与技术学院, 讲师、硕士生导师(破格)
2021.9 -至今,山东理工大学,生命与医药学院,特聘教授、博士生导师
科研成果
1. 科研项目
国家自然科学基金面上项目,31870689,梅花垂枝性状的关联分析及遗传机理解析,2019/01-2022/12,60万元,在研,参加
国家自然科学基金国际合作与交流项目,3181101067,功能表型联姻功能作图:植物复杂性状农艺耐旱性解析的新途径,2018/10-2021/12,160万,在研,参加
国家自然科学基金青年项目,31700576,林木复杂性状系统作图计算平台构建,2018/01-2020/12,25万元,结题,主持
北京林业大学科技创新计划项目,BLX201715,基于博弈论的基因调控网络重构,2018/01-2019/12,8万元,结题,主持
国家自然科学基金委员,面上项目,31971398,全基因组系统作图(systems mapping)研究三种细菌种间互作遗传机制,2020-01至2023-12, 58万元,在研,参加
国家自然科学基金委员会, 面上项目, 31971681, 基于异速生长理论的旱柳根系耐盐基因网络枢纽发掘, 2020-01至2023-12, 58万元, 在研, 参加
国家自然科学基金委员会, 面上项目, 31971620, 基于精细取样和时空转录组等分析杨树维管形成层周期性活动规律和调控机制, 2020-01至2023-12, 58万元, 在研,参加
国家自然科学基金委员会,面上项目,32070601,复杂性状博弈作图模型构建与应用,2021-01至2024-12, 58万元,在研,主持
2. 科研成果与奖励
针对复杂性状这一当代生物学最具有挑战性的难题,发展统计模型和计算机算法对其内在的遗传机制进行解析,近几年来取得了一批具有国际影响力的突破性研究成果,发表40余篇SCI论文,分别收录在Nature Communications、iScience, Trends in Genetics和Briefings in Bioinformatics等国际著名期刊,并获3项国家发明专利授权。具体如下所示:
①代表性论文
[1] Rongling Wu, Libo Jiang. Recovering dynamic networks in big static datasets. Physics Reports, 2021.
[2] Libo Jiang, Christopher H. Griffin, Rongling Wu. SEGN: Inferring real-time gene networks mediating phenotypic plasticity. Computational and Structural Biotechnology Journal, 2020, 18: 2510-2521.
[3] Libo Jiang, Xiang yu Ren, Rongling Wu. Computational characterization of double reduction in autotetraploid natural populations. The Plant Journal, 2020.
[4] Qianru Zhang, Zhifang Su, Yunqian Guo, Shilong Zhang, Libo Jiang*, and Rongling Wu. Genome-wide association studies of callus differentiation for the desert tree, Populus euphratica. Tree Physiology, 2020, 40(12): 1762-1777.
[5] Libo Jiang#, Xinjuan Liu#, Xiaoqing He, Yi Jin, Yige Cao, Xiang Zhan, Christopher H. Griffin, Claudia Gragnoli, Rongling Wu. A behavioral model for mapping the genetic architecture of gut-microbiota networks. Gut Microbes, 2020: 1-15.
[6] Jingwen, Gan, Yige Cao, Libo Jiang*, Rongling Wu. Mapping Covariation Quantitative Trait Loci That Control Organ Growth and Whole-Plant Biomass.Frontiers in Plant Science, 2019, 10: 719.
[7] Ping Wang, LiboJiang*, Meixia Ye, Xuli Zhu, Rongling Wu. The genomic landscape of crossover interference in the desert tree Populus euphratica. Frontiers in Genetics, 2019, 10: 440.
[8] Libo Jiang#, Jian Xu#, Mengmeng Sang, Yan Zhang, Meixia Ye, Hanyuan Zhang, Biyin Wu, Youxiu Zhu, Peng Xu, Ruyu Tai, Zixia Zhao, Yanliang Jiang, Chuanju Dong, Lidan Sun, Christopher H. Griffin, Claudia Gragnoli, Rongling Wu*. A Drive to Driven Model of Mapping Intraspecific Interaction Networks.iScience, 2019, 22: 109-122.
[9] Libo Jiang, Lidan Sun, Meixia Ye, Jing Wang, Yaqun Wang, Matthieu Bogard*, Xavier Lacaze, Antoine Fournier, Katia Beauchêne, David Gouache, Rongling Wu*. Functional mapping of N deficiency-induced response in wheat yield-component traits by implementing high-throughput phenotyping. The Plant Journal, 2019, 97(6), 1105-1119.
[10] Libo Jiang#, Xiaoqing He#, Yi Jin#, Meixia Ye#, Mengmeng Sang, Nan Chen, Jing Zhu, Zuoran Zhang, Jinting Li, Rongling Wu*.A mapping framework of competition-cooperation QTLs that drive community dynamics. Nature Communications, 2018, 9(1): 3010.
[11]Libo Jiang,Chaozhong Shi, Meixia Ye, Feifei Xi, Yige Cao, Lina Wang, Miaomiao Zhang, Mengmeng Sang, Rongling Wu*. A computational-experimental framework for mapping plant coexistence. Methods in Ecology and Evolution, 2018, 9(5): 1335-1352.
[12]Libo Jiang, Miaomiao Zhang, Mengmeng Sang, Meixia Ye, Rongling Wu*. Evo-Devo-EpiR: a genome-wide search platform for epistatic control on the evolution of development. Briefings in Bioinformatics, 2017, 18(5): 754-760.
[13] Libo Jiang#, Meixia Ye#, Sheng Zhu#, Yi Zhai, Meng Xu, Minren Huang, Rongling Wu*. Computational identification of genes modulating stem height-diameter allometry. Plant Biotechnology Journal, 2016, 14(12), 2254-2264.
[14] Xuli Zhu#, Libo Jiang#, Meixia Ye#, Lidan Sun, Claudia Gragnoli, Rongling Wu*. Integrating evolutionary game theory into mechanistic genotype-phenotype mapping. Trends in Genetics, 2016, 32(5): 256-268.
[15]Libo Jiang#, Jingyuan Liu#, Xuli Zhu, Meixia Ye, Lidan Sun, Xavier Lacaze, Rongling Wu*. 2HiGWAS: a unifying high-dimensional platform to infer the global genetic architecture of trait development. Briefings in Bioinformatics, 2015, 16(6): 905-911.
[16] Libo Jiang#, Jose A. Clavijo#, Lidan Sun#, Xuli Zhu, Mehul S. Bhakta, Salvador A. Gezan, Melissa Carvalho, C. Eduardo Vallejos*, Rongling Wu*. Plastic expression of heterochrony quantitative trait loci (hQTLs) for leaf growth in the common bean (Phaseolus vulgaris). New Phytologist, 2015, 207(3): 872-882.
②专利
[1] 姜立波,邬荣领, 冯思思. 一种同源四倍体自然群体的连锁不平衡分析模型的构建. 2017.06, 中国, ZL201410013164.8
[2] 邬荣领, 姜立波, 张健, 王晶, 叶梅霞. 基于基因调控网络的胡杨无性系选育方法. 2017.08, 中国, ZL201410532492.9
[3] 邬荣领, 姜立波, 张健, 王晶, 张苗苗. 基于基因与蛋白调控网络的林木精确育种方法和系统. 2018.03, 中国, ZL201410532915.7
③参编专著
[1] Lidan Sun, Libo Jiang, Meixia Ye, Xuli Zhu, Jing Wang, Kirk Gosik, Rongling Wu. Functional Mapping: How to Map Genes for Phenotypic Plasticity of Development. Evolutionary Biology: Biodiversification from Genotype to Phenotype. Springer International Publishing, 2015: 3-17.
[2] Kaiyue Liu, Wenhao Bo, Lina Wang, Rongling Wu, Libo Jiang*. (2018). Functional Mapping of Plant Growth in Arabidopsis thaliana. In Next Generation Plant Breeding. IntechOpen.
④获得的学术奖励
[1] 姜立波,2HiGWAS: a unifying high-dimensional platform to infer the global genetic architecture of trait development,中国林学会,梁希青年论文奖,二等奖,2016
[2] 姜立波(2/7),林木数量性状基因解析理论与方法,北京市,北京市科学技术奖,三等奖,2017(邬荣领,姜立波,薄文浩,孙丽丹,庞晓明,王忠,叶梅霞)
[3] 姜立波(2/5),复杂性状功能作图理论,教育部,高等学校科学研究优秀成果奖(自
然科学奖),二等奖,2017(邬荣领,姜立波,薄文浩,孙丽丹,叶梅霞)
[4] 姜立波,A mapping framework of competition-cooperation QTLs that drive community dynamics,中国林学会,梁希青年论文奖,二等奖,2020
社会兼职
中国林学会会员,担任期刊Frontiers in Genetics编辑,以及Briefings in Bioinformatics,Heredity,BMC Genetics,BMC Genomic等期刊的审稿人。
荣誉称号
山东省泰山学者青年专家