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胡博 博士后    

2022年9月毕业于山东师范大学化学院,获理学博士学位,导师为徐克花教授。主要研究方向为纳米诊疗探针的设计、合成及生物应用。近年来发展了多种性能优良的纳米荧光探针,实现了疾病相关重要活性分子的高灵敏识别、成像,并将其应用于相关生理病理过程的检测与调控。在学术期刊发表论文14篇,其中以第一作者在Angew. Chem. Int. Ed.,Biomaterials,ACS Appl. Mater. Inter.,Anal. Chem.,Sensor. Actuat. B-Chem.等杂志发表论文7篇。

主持科研项目

中国博后基金面上资助(2023M731857)

山东省自然科学基金青年项目(ZR202211150201)

青岛市博士后项目资助4030431060114

湖南大学重点实验室开放课题202301010365

代表性论文

1. Bo Hu, Fanpeng Kong, Xiaonan Gao, Lulu Jiang, Xiaofeng Li, Wen Gao, Kehua Xu*, Bo Tang*. Avoiding Thiol Compound Interference: A Nanoplatform Based on High-Fidelity Au–Se Bonds for Biological Applications. Angewandte Chemie-International Edition, 2018, 57(19):5306-5309.

2. Bo Hu, Ranran Cheng, Xiaojun Liu, Xiaohong Pan, Fanpeng Kong, Wen Gao, Kehua Xu*, Bo Tang*. A nanosensor for in vivo selenol imaging based on the formation of Au-Se bonds. Biomaterials, 2016, 92: 81-89.

3. Bo Hu, Ranran Cheng, Xiaonan Gao, Xiaohong Pan, Fanpeng Kong, Xiaojun Liu, Kehua Xu*, Bo Tang*. Targetable Mesoporous Silica Nanoprobes for Mapping the Subcellular Distribution of H2Se in Cancer Cells. ACS Applied Materials & Interfaces, 2018, 10(20):17345-17351.

4. Bo Hu, Qin Zhang, Xiaonan Gao, Kehua Xu*, Bo Tang*. Monitoring the Activation of Caspases-1/3/4 for Describing the Pyroptosis Pathways of Cancer Cells. Analytical Chemistry, 2021, 93(35):12022-12031.

5.  Bo Hu, Zengteng Zhao, Xiaonan Gao, Xiaoxiao Song, Zihao Xu, Bo Tang, Kehua Xu*. Se-modified gold nanorods for enhancing the photothermal therapy efficiency--avoiding the off-target problem induced by biothiols. Journal of Materials Chemistry B, 2021, 9(42): 8832-8841.

6. Bo Hu, Qin Zhang, Xiaoyi Lv, Xiaonan Gao, Xiaojun Liu, Kehua Xu*and Bo Tang*. Acidic-driven aggregation of selenol-functionalized zwitterionic gold nanoparticles improves photothermal treatment efficacy of tumors. Materials Chemistry Frontiers, 2022, 6: 775-782.

7. Xiaonan Gao#, Bo Hu#, Zengteng Zhao, Tianrun Niu, Yifan Liu, Kehua Xu*, Bo Tang. Synthesis of Au-Se Bonded Nanoprobe for Specific Detection of Thrombin in Lung Cancer Cells. Sensors and Actuators B: Chemical, 2022, 352(1):130999.