Email: 9321512262@qq.com
微信公众号:ALMD-KUST
实验室网址:https://www.x-mol.com/groups/ALMD
地址:昆明理工大学(莲华校区),材料科学与工程学院
个人简介:
何佳,女,四川广元人,2023年9月在四川大学获得化学博士学位,2023年12月以昆明理工大学“高层人人才引进”入职材料科学与工程学院。从事体外诊断、生物医学组织工程的研究,从事柔性可穿戴传感器的研究。在体外诊断材料的制备上,研究了二维纳米片上MOFs的原位生长以及分级多孔结构的调控,实现了对IMAC、MOCA以及基于亲水作用的功能性亲和材料的设计、制备与性能优化,实现对磷酸化肽段的高效富集。在纳米级器件的制备与优化上,综合进行纳米材料设计、掺杂和复合改性、微观结构调制、界面调控、器件结构设计,为实现不同工作场景下器件化运用提供了基础。在柔性可穿戴传感器的研究上,通过利用各种物理、化学和生物传感器以无创或微创方式实时挖掘生理(生物物理和/或生化)信息,为临床诊断提供了替代途径。在Materials&Design、Journal of Colloid and Interface Science、Acs Applied Materials & Interfaces、Journal of Materials Chemistry B等期刊发表 SCI 论文 15篇。申请发明专利 1 项,参与了 2 项国家自然科学基金,1 项四川省科技计划项目。
研究方向:
1.新型框架多孔复合材料的制备及其在体外诊断中的应用;
2.柔性可穿戴技术。
教育经历:
1. 2018-09至2023-09,四川大学,生物医学工程学院,博士
2. 2014-09至2018-06,东北师范大学,化学学院,学士
在研项目:
1.昆明理工大学高层次人才培养经费,80万,2024.02-2032.02,主持。
代表性论文:
1. Jia He, Bin Luo, Huinan Zhang, Zhiyu Li, Nanhang Zhu, Fang Lan , Yao Wu. Surfactant-free synthesis of covalent organic framework nanospheres in water at room temperature. Journal of Colloid and Interface Science, 2022, 606, 1333-1339.
2. Jia He, Lingzhu Yu, Zhiyu Li, Shengdong Ba, Fang Lan, Yao Wu. Catalyst regulated interfacial synthesis of self-standing covalent organic framework membranes at room temperature for molecular separation. Journal of colloid and interface science, 2022, 629, 428-437.
3. Jia He, Lingzhu Yu, Bin Luo, Yicheng Liu, Fang Lan, and Yao Wu. Dielectric barrier discharge induced Oxid-Ti3C2Tx/UIO-66-NH2 Composites for efficient phosphopeptides enrichment. Materials&Design233(2023)112193.
4. Bin Luo, Jia He, Zhiyu Li, Fang Lan, Yao Wu. Glutathione-Functionalized Magnetic Covalent Organic Framework Microspheres with Size Exclusion for Endogenous Glycopeptide Recognition in Human Saliva. Acs Applied Materials & Interfaces, 2019, 11, 47218-47226.
5. Lingzhu Yu, Jia He, Shuang Yan, Yicheng Liu, Fang Lan, and Yao Wu. Magnetic MXene/PAMAM Composites with Flexible Dimensional Regulation for Highly Effective Enrichment of Phosphopeptides. ACS Sustainable Chemistry & Engineering 2022 10 (7), 2494-2508.
6. Luo Bin, Li Guohao, Li Zhiyu, He Jia, Zhou Juan, Wu Lijuan, Lan Fang, Wu Yao, Construction of a magnetic covalent organic framework with synergistic affinity strategy for enhanced glycopeptide enrichment. Journal of Materials Chemistry B, 2021, 9, 6377-6386.
7. Bin Luo, Lingzhu Yu, Jia He, Zhiyu Li, Fang Lan, Yao Wu, Magnetic polymer nanomaterials for sample pretreatment in proteomicst. Materials Advances, 2021, 2, 2200-2215.
8. Shuang Yan, Bin Luo, Jia He, Fang Lan, Yao Wu, Phytic acid functionalized magnetic bimetallic metal-organic frameworks for phosphopeptide enrichment. Journal of Materials Chemistry B, 2021, 9, 1811-1820.
9. Bin Luo, Lingzhu Yu, Zhiyu Li, Jia He, Chunjie Li, Fang Lan* and Yao Wu, Complementary multiple hydrogenbond-based magnetic composite microspheres for high coverage and efficient phosphopeptide enrichment in bio-samples. Journal of Materials Chemistry B, 2020, 8, 8414-8421.
10. Lingzhu Yu, Bin Luo, Zhiyu Li, Jia He, Fang Lan, Yao Wu, PAMAM-PMAA brush-functionalized magnetic composite nanospheres: a smart nanoprobe with tunable selectivity for effective enrichment of mono-, multi-, or globalphosphopeptides. Journal of Materials Chemistry B, 2020, 8, 1266-1276.
11. Bin Luo, Qiang Chen, Jia He, Zhiyu Li, Lingzhu Yu, Fang Lan, Yao Wu, Boronic Acid-Functionalized Magnetic Metal-Organic Frameworks via a Dual-LigandStrategy for Highly Efficient Enrichment of Phosphopeptides and Glycopeptides. Acs Sustainable Chemistry & Engineering, 2019, 7, 6043-6052.
12. Bin Luo, Lingzhu Yu, Jia He, Zhiyu Li, Fang Lan, Yao Wu, Design of guanidyl-functionalized magnetic covalent organic framework for highly selective capture of endogenous phosphopeptides. Journal of Chromatography B 1145 (2020) 122080.
13. Shengdong Ba, Bin Luo, Zhiyu Li, Jia He, Fang Lan, Yao Wu, Mesoporous covalent organic framework microspheres with dual-phase separation strategy for high-purity glycopeptide enrichment. Journal of Chromatography A 1684 (2022) 463575.
专利情况:
1.蓝芳,何佳,吴尧,一种介质阻挡放电诱导Oxid-Ti3C2Tx/UIO-66-NH2复合材料的制备方法及其应用,2023-06-16,中国,202310717370.6