In patients with symptomatic paroxysmal atrial fibrillation, pulsed field ablation is non-inferior to cryoballoon ablation for preventing the recurrence of atrial tachyarrhythmia, according to findings from the SINGLE SHOT CHAMPION trial.

Two clinical trials presented at the ACC.25 describe the expanding indications for the glucagon-like peptide 1 receptor agonist semaglutide in patients with type 2 diabetes mellitus.

Findings from the BHF PROTECT-TAVI trial indicate that the routine use of cerebral embolic protection devices during transcatheter aortic valve implantation does not decrease the incidence of stroke within 72 h after the intervention.

Researchers have engineered a millimetre-scale, bioresorbable, optoelectronic system that can be minimally invasively implanted into the heart and wirelessly controlled by a light source on the surface of the skin to provide temporary cardiac pacing.

Mia Manojlovic and Melaku Taye Amogne highlight the 1986 study that unravelled the primary structure of apolipoprotein B100 and laid a foundation for subsequent studies on the role of this apolipoprotein.

Hooi Min Lim describes how the Bogalusa Heart Study emphasized the importance of primordial prevention of cardiovascular disease and profoundly influenced subsequent cardiovascular research on children and adolescents.