陈家念 - 广西师范大学 - 化学与药学学院

研究领域

主要研究和感兴趣的领域： 1. Me-too药物设计、合成及构效关系研究； 2. 药物新剂型研究，特别是肿瘤靶向递药系统的构建及性能评价。

近期论文

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Jianian Chen, Shaoshun Li, Qi Shen, Folic acid and cell-penetrating peptide conjugated PLGA-PEG bifunctional nanoparticles for vincristine sulfate delivery, European Journal of Pharmaceutical Sciences, 2012, 47(2): 430 – 443. (SCI, 医学三区) Jianian Chen, Huijuan He, Shaoshun Li, Qi Shen, An HPLC method for the pharmacokinetic study of vincristine sulfate-loaded PLGA–PEG nanoparticle formulations after injection to rats, Journal of Chromatography B, 2011, 879(21): 1967 – 1972. (SCI, 医学三区) Jianian Chen, Shaoshun Li, Qi Shen, Huijuan He, Yi Zhang, Enhanced cellular uptake of folic acid-conjugated PLGA–PEG nanoparticles loaded with vincristine sulfate in human breast cancer, Drug Development and Industrial Pharmacy, 2011, 37(11): 1339 – 1346. (SCI, 医学四区) Tiecheng Zhang, Jianian Chen, Qi Shen, Weisan Pan, Characterization and evaluation of nanostructured lipid carrier as a vehicle for oral delivery of etoposide，European Journal of Pharmaceutical Sciences, 2011, 43(3):174 – 179. (SCI, 医学三区) Jianian Chen, Guichun Yang, Haiqing Zhang, Zuxing Chen, A review: Non-cross-linked polystyrene bound reagents, catalysts and syntheses, Reactive and Functional Polymers, 2006, 66(12): 1434 – 1451. (SCI, 工程二区) Jianian Chen, Junqi Nie, Yanling Huang, Zuxing Chen，Guichun Yang, Synthesis of a new chiral auxiliary: non-cross-linked polystyrene bound (4S)-oxazolidine-2-thione, Journal of Chemical Research, 2006, 696 – 697. Haiqing Zhang, Guichun Yang, Jianian Chen, Zuxing Chen, Synthesis of thiophene derivatives on soluble polymer-support using Gewald reaction, Synthesis, 2004, 18: 3055 – 3059. (SCI, 化学三区) Haiqing Zhang, Guichun Yang, Jianian Chen, Zuxing Chen, Gewald synthesis of 2-aminothiophenes on a soluble polymer-support, Journal of Chemical Research, 2004, 360 – 361. 陈家念，沈琦，李绍顺，纳米粒给药系统逆转肿瘤多药耐药性的研究进展, 药学学报, 2009, 44(4): 333 – 337. (中文核心期刊)