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研究领域

手性化合物分离分析、天然药物的提取分离与结构改造。

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Xiao-Chao Huang, Meng Wang, Ying-Ming Pan, Gui-Yang Yao, Heng-Shan Wang*, Xiao-Yan Tian, Jiang-Ke Qin, Ye Zhang*. Synthesis and antitumor activities of novel thiourea α-aminophosphonates from dehydroabietic acid. European Journal of Medicinal Chemistry. 2013, 69: 508–520. Man-Yi Ye, Gui-Yang Yao, Ying-Ming Pan, Zhi-Xin Liao, Ye Zhang, Heng-Shan Wang. Synthesis and antitumor activities of novel α-aminophosphonate derivatives containing an alizarin moiety. European Journal of Medicinal Chemistry. 2014, 83(18): 116–128 Jian-Fei Li, Ri-Zhen Huang, Gui-Yang Yao, Man-Yi Ye, Heng-Shan Wang, Ying-Ming Pan, Jing-Teng Xiao. Synthesis and biological evaluation of novel aniline-derived asiatic acid derivatives as potential anticancer agents. European Journal of Medicinal Chemistry, 2014, 86(30), 175-188 Gui-yang Yao, Man-yi Ye, Ri-zhen Huang, Ya-jun Li, Ying-ming Pan, Qing Xu, Zhi-Xin Liao*, Heng-shan Wang*. Synthesis and antitumor activities of novel rhein α-aminophosphonates conjugates. Bioorganic & Medicinal Chemistry Letters. 2014, 24(2): 501–507 Xiao-Chao Huang, Meng Wang, Ying-Ming Pan, Xiao-Yan Tian, Heng-Shan Wang*, Ye Zhang*. Synthesis and antitumor activities of novel α-aminophosphonates dehydroabietic acid derivatives. Bioorganic & Medicinal Chemistry Letters. 2013, 23(19): 5283–5289 Xiao-Chao Huang, Meng Wang, Heng-Shan Wang*, Zhen-Feng Chen, Ye Zhang*, Ying-Ming Pan. Synthesis and antitumor activities of novel dipeptide derivatives derived from dehydroabietic acid. Bioorganic & Medicinal Chemistry Letters. 2014, 24(6): 1511–1518 Gui-yang Yao, Man-yi Ye, Ri-zhen Huang, Ya-jun Li, Yong-tao Zhu, Ying-ming Pan, Zhi-Xin Liao*, Heng-shan Wang*. Synthesis and antitumor activity evaluation of maleopimaric acid N-aryl imide atropisomers. Bioorganic & Medicinal Chemistry Letters.2013, 23(19): 5283–5289 Ying-Chun Wang, Yu-Yang Xie, Hong-En Qu, Heng-Shan Wang*, Ying-Ming Pan, and Fu-Ping Huang. Ce(OTf)3- Catalyzed [3 + 2] Cycloaddition of Azides with Nitroolefins: Regioselective Synthesis of 1,5-Disubstituted 1,2,3- Triazoles, J. Org. Chem., 2014, 79, 4463-4469. Yan-li Xu, Ying-ming Pan*, Qiang Wu, Heng-shan Wang* and Pei-zhen Liu. Regioselective Synthesis of 1,3,5-Substituted Benzenes via the InCl3/2-Iodophenol- Catalyzed Cyclotrimerization of Alkynes. J. Org. Chem. 2011, 76 (20): 8472–8476. Yu-Yang Xie, Ying-Chun Wang, Hong-En Qu, Xian-Chun Tan, Heng-Shan Wang*, and Ying-Ming Pan*. Regioselective Synthesis of β-Aryl Enaminones and 1,4,5-Trisubstituted 1,2,3-Triazoles from Chalcones and Benzyl Azides, Advanced Synthesis &Catalysis. 2014, in press. Xu Wang, Ying-ming Pan*, Xiao-chao Huang, Zhong-yuan Mao and Heng-shan Wang* A novel methodology for synthesis of dihydropyrazole derivatives as potential anticancer agents, Org. Biomol. Chem., 2014, 12: 2028-2032. Pei Liu, Yingming Pan*, Yanli Xu, Hengshan Wang*. PTSA-catalyzed Mannich- type–cyclization –oxidation tandem reactions: one-pot synthesis of 1,3,5-substituted pyrazoles from aldehydes, hydrazines and alkynes. Organic & Biomol. Chem., 2012, 10: 4696–4698. Guiyang Yao, Yajun Li, Yongtao Zhu, Yingming Pan, Fuping Huang, Hengshan Wang* and Zhixin Liao*. Protonation-controlled axial chirality in maleopimaric imides. New J. Chem., 2014, 38, 693-699. Ying-Chun Wang, Heng-Shan Wang*, Guo-Bao Huang, Fu-Ping Huang, Kun Hu, Ying-Ming Pan*.A one-pot approach to 4,5-dihydropyrazoles from ketones, arylacetylenes, and hydrazines. Tetrahedron. 2014, 70(8): 1621–1628. Qi Gao, Shenyan Li, Yingming Pan, Yanli Xu, Hengshan Wang. The indium-catalysed hydration of alkynes using substoichiometric amounts of PTSA as additive. Tetrahedron, 69(19): 3775-3781 Pingtan Lin, Shulin Zhao*, Xin Lu, Fanggui Ye, Hengshan Wang*. Preparation of a dual‐enzyme co‐immobilized capillary microreactor and simultaneous screening of multiple enzyme inhibitors by capillary electrophoresis, Journal of Separation Science, 2013, 36(15): 2538–2543. Man-Yi Ye, Gui-Yang Yao, Jing-Chen Wei, Ying-Ming Pan*, Zhi-Xin Liao and Heng-Shan Wang*. Synthesis, Cytotoxicity, DNA binding and Apoptosis of Rhein Phosphonate Derivatives as Antitumor Agents. Int. J. Mol. Sci. 2013, 14, 9424-9439. Hengshan Wang*, Xiaoyan Tian, Da Yang, Yingming Pan, Qiang Wu, Chunhuan HeSynthesis and enantiomeric recognition ability of 22-crown-6 ethers derived from rosin acid and BINOL Tetrahedron: Asymmetry, 2011, 22: 381–386. Ming-xiong Tan, Dian-hua Gan, Liu-xin Wei, Ying-ming Pan, Shao-qing Tang, Heng-shan Wang* Isolation and characterization of pigment from Cinnamomum burmannii’ peel. Food Research International, 2011, 44: 2289-2294. Hengshan Wang*, Chunhuan He, Yingming Pan, Guiyang Yao, Qiang Wu and Honggui Deng. Synthesis and amines enantiomeric recognition ability of binaphthyl-appended 22-crown-6 ethers derived from rosin acid. J Inclusion Phenomena and Macrocyclic Chemistry, 2011, DOI 10.1007/s10847-011-0040-5

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