研究领域
主要研究和感兴趣的领域：
1）基于多靶向策略的氧化阿扑菲和氧化异阿扑菲生物碱的结构修饰以及抗老年痴呆症活性研究。
2）新型兽用抗生素以及缓释制剂的合成与开发。
近期论文
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HAI-TAO ZHAO, SHU-MING ZHONG, JIANG-KE QIN and Huang Tang*. Novel Hybrids of Oxoisoaporphine-Tryptamine as Acetylcholinesterase-induced β-amyloid Aggregation Inhibitors, with Improved Antioxidant Properties. J. Ser. Chem. Soc. 2014, doi: 10.2298/JSC140319092Z.(SCI收录)
Wei Chena, Yuhuan Wub, Shuming Zhongb, Ling Chenga, Qinghua Li, Huang Tang*. Anti-neurotoxicity effects of oxoisoaporphine-lipoic acid hybrids. Chem-Biol. Interact. 2014, 223(5): 45–50. (SCI收录，影响因子3.154)
Zhong, Shuming; Wei, Shenqi; Liu, Yun; Tang, Huang*. Synthesis and Biological Evaluation of 6-[(Alkylamino) hydrazide-yl]-1-azabenzanthrone Derivatives. Chin. J. Org. Chem. 2014, 1: 137-146. (SCI收录)
Tang Huang , Hao-Tao Zhao, Shu-Ming Zhong, Zhi-Yu Wang, Zhen-Fen Chen. Novel Oxoisoaporphine-Based Inhibitors of Acetyl- and Butyrylcholinesterase and Acetylcholinesterase-Induced beta-Amyloid Aggregation. Bioorg. Med. Chem. Lett. 2012,22：2257-2261. (SCI收录，影响因子2.661)
Tang Huang; Zhao, L.-Z.; Zhao, H.-T.; Huang, S.-L.; Zhong, S.-M.; Qin, J.-K.; Chen, Z.-F.; Huang, Z.-S.; Liang, H., Hybrids of oxoisoaporphine-tacrine congeners: Novel acetylcholinesterase and acetylcholinesterase-induced beta -amyloid aggregation inhibitors. Eur. J. Med. Chem.2011, 46, (10), 4970-4979. (SCI收录，影响因子3.193)
Tang Huang, X.Dong Wang, Y.Biao Wei, S.Liang Huang, Z.Shu Huang, J.Heng Tan, L.Kun An, J.Yong Wu, A. Sun-Chi Chan, L.Quan Gu. Oxoisoaporphine Alkaloid Derivatives: Synthesis, DNA Binding Affinity and Cytotoxicity, Eur. J. Med. Chem. 2008, 43, 973-980. (SCI收录，影响因子2.882)
Huang Tang, F-X. Ning, Y-B. Wei, S-L. Huang, Z-S. Huang, A.S-C. Chan, L-Q. Gu. Derivatives of Oxoisoaporphine Alkaloids: A novel class of selective acetylcholinesterase inhibitors, Bioorg. Med. Chem. Lett. 2007, 17(13), 3765-3768. (SCI收录，影响因子2.56)
Tang. Huang, Y.Biao Wei, Chi Zhang, Fang-Xian Ning, Wei Qiao , Shi-Liang Huang, Lin M, Zhi-Shu Huang, Lian-Quan Gu. Synthesis, biological evaluation and molecular modeling of oxoisoaporphine and oxoaporphine derivatives as new dual inhibitors of acetylcholinesterase/butyrylcholinesterase." Eur. J. Med. Chem. 2009, 44(6), 2523-2532. (SCI收录，影响因子2.882)
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