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个人简介

EDUCATION and TRAINING 1999-2003: Dalian University of Technology, China, B.S., Polymer 2003-2009: Dalian University of Technology, China, Ph. D., Biochemical engineering 2009-2011: Dalian University of Technology, China, Postdoctoral fellow, Biomedical engineering Current grant support: 1. Fundamental Research Funds for the Central Universities (No.DUT19LAB17, 2019.01-2020.12) 2. Dalian Major Research and Development Program (2018.01-2020.12) 3. Dalian High Level Talent Innovation Support Project (No.2016RQ023, 2016.10-2019.09) 4. National Major Research and Development Program (No.2016YFC1103000, 2016.06-2020.12)

研究领域

1. Bioseparation techniques for protein purification. 2. Biomedical materials for blood purification treatments.

近期论文

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Meng, X.; Xiong, H.; Ji, F.; Gao, X.; Han, L.; Wu, Z.; Jia, L; Ren, J.*, Facile surface treatment strategy to generate dense lysozyme layer on ultra-high molecular weight polyethylene enabling inhibition of bacterial biofilm formation. Colloids and Surfaces B: Biointerfaces 2023, 225:113243. Ren, J.; Xiong, H.; Huang, C.; Ji, F.; Jia, L.*, An engineered peptide tag-specific nanobody for immunoaffinity chromatography application enabling efficient product recovery at mild conditions. Journal of Chromatography A 2022, 1676: 463274. Ren, J.; Meng, X.; Xiang, X; Ji, F.; Gao, X.; Han, L.; Jia, L*. Tyrosine-based dual-functional interface for trapping and on-site photo-induced covalent immobilization of proteins. Bioconjugate Chemistry 2022, 33 (5): 829-838 Ren, J.; Xiang, X; Ji, F.; Gao, X.; Han, L.; Jia, L*. Benzotriazole-5-carboxylic as a mixed-mode ligand for chromatographic separation of antibody with enhanced adsorption capacity. Journal of Chromatography B 2021, 1179:122652. Ren, J.; Zhang, C.; Ji, F.; Jia, L.*, Characterization and comparison of two peptide-tag specific nanobodies for immunoaffinity chromatography. Journal of Chromatography A 2020, 1624: 461227. Huang, C.; Ren, J.*; Ji, F.; Muyldermans, S.; Jia, L.*, Nanobody-Based high-performance immunosorbent for selective beta 2-microglobulin purification from blood. Acta Biomaterialia 2020, 107: 232-241. Peng, Q.; Zang, B.; Zhao, W.; Li, D.; Ren, J.; Ji, F.; Jia, L.*,Efficient continuous-flow aldehyde tag conversion using immobilized formylglycine generating enzyme. Catalysis Science & Technology 2020, 10(2): 484-492. Bao X.; Ren J.; Wang Y.; Jia L.*, Quantitative determination of the beta-2-microglobulin monomer by gel filtration chromatography, Chinese Journal of Chromatography 2019, 37(5): 533-538. Zang, B.; Ren, J.; Li, D.; Huang, C.; Ma, H.; Peng, Q.; Ji, F.; Han, L.; Jia, L.*, Freezing-assisted synthesis of covalent C–C linked bivalent and bispecific nanobodies. Organic & Biomolecular Chemistry 2019, 17(2), 257-263. Long, X.; Ren, J.*; Zhang, C.; Ji, F.; Jia, L., Facile and Controllable Fabrication of Protein-Only Nanoparticles through Photo-Induced Crosslinking of Albumin and Their Application as DOX Carriers. Nanomaterials 2019, 9:5. Ren, J.; Tian, K.; Jia, L.*; Han, X.; Zhao, M., Rapid covalent immobilization of proteins by phenol-based photochemical cross-linking. Bioconjugate Chemistry 2016, 27 (10), 2266-2270. Gao, M.; Ren, J.*; Tian, K.; Jia, L.*V, Characterization of non-specific protein adsorption induced by triazole groups on the chromatography media using Cu (I)-catalyzed alkyne-azide cycloaddition reaction for ligand immobilization. Journal of Chromatography A 2016, 1476, 63-68. Zang, B.; Ren, J.*; Xu, L.; Jia, L.*, Direct site-specific immobilization of protein A via aldehyde-hydrazide conjugation. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences 2016, 1008, 132-138. Han, L.; Chu, S.; Wei, H.; Ren, J.; Xu, L.; Jia, L.*, Functionalized magnetic Fe3O4-beta-cyclodextran nanoparticles for efficient removal of bilirubin. Journal of Nanoscience and Nanotechnology 2016, 16 (6), 5537-5545. Yang, L.; Han, L.; Ren, J.; Wei, H.; Jia, L.*, Coating process and stability of metal-polyphenol film. Colloids and Surfaces a-Physicochemical and Engineering Aspects 2015, 484, 197-205. Wei, H.; Han, L.; Tang, Y.; Ren, J.; Zhao, Z.; Jia, L.*, Highly flexible heparin-modified chitosan/graphene oxide hybrid hydrogel as a super bilirubin adsorbent with excellent hemocompatibility. Journal of Materials Chemistry B 2015, 3 (8), 1646-1654. Ren, J.; Han, P.; Wei, H.; Jia, L.*, Fouling-resistant behavior of silver nanoparticle-modified surfaces against the bioadhesion of microalgae. ACS Applied Materials & Interfaces 2014, 6 (6), 3829-3838. Ren, J.; Yao, P.; Cao, Y.; Cao, J.; Zhang, L.; Wang, Y.; Jia, L.*, Application of cyclodextrin-based eluents in hydrophobic charge-induction chromatography: Elution of antibody at neutral pH. Journal of Chromatography A 2014, 1352, 62-68. Ren, J.; Yao, P.; Chen, J.; Jia, L.*V, Salt-independent hydrophobic displacement chromatography for antibody purification using cyclodextrin as supermolecular displacer. Journal of Chromatography A 2014, 1369, 98-104. Xu, L.; Wang, C.; Chen, L.; Ren, J.; Xie, J.; Jia, L.*, Detection of A beta-interacting proteins via a novel A beta-adsorbents that use immobilized regular comb polymer. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences 2014, 971, 94-98. Ren, J.; Wang, L.; Han, X.; Cheng, J.; Lv, H.; Wang, J.; Jian, X.; Zhao, M.; Jia, L.*, Organic silicone sol-gel polymer as a noncovalent carrier of receptor proteins for label-free optical biosensor application. ACS Applied Materials & Interfaces 2013, 5 (2), 386-394. Wei, H.; Han, L.; Ren, J.; Jia, L.*, Anticoagulant surface coating using composite polysaccharides with embedded heparin-releasing mesoporous silica. ACS Applied Materials & Interfaces 2013, 5 (23), 12571-12578. Wei, H.; Ren, J.; Han, B.; Xu, L.; Han, L.; Jia, L.*, Stability of polydopamine and poly(DOPA) melanin-like films on the surface of polymer membranes under strongly acidic and alkaline conditions. Colloids and Surfaces B-Biointerfaces 2013, 110, 22-28. Wang, L.; Ren, J.; Han, X.; Claes, T.; Jian, X.; Bienstman, P.; Baets, R.; Zhao, M.*; Morthier, G., A label-free optical biosensor built on a low-cost polymer platform. IEEE Photonics Journal 2012, 4 (3), 920-930. Wei, H.; Xu, L.; Ren, J.; Jia, L.*, Adsorption of bilirubin to magnetic multi-walled carbon nanotubes as a potential application in bound solute dialysis. Colloids and Surfaces a-Physicochemical and Engineering Aspects 2012, 405, 38-44. Ren, J.; Bai, Y.; Hao, L.; Dong, Y.; Pi, Z.; Jia, L.*, Amelioration of experimental autoimmune myasthenia gravis rats by blood purification treatment using 4-mercaptoethylpyridine-based adsorbent. Journal of Biomedical Materials Research Part A 2011, 98A (4), 589-595. Ren, J.; Jia, L.*; Xu, L.; Lin, X.; Pi, Z.; Xie, J., Removal of autoantibodies by 4-mercaptoethylpyridine-based adsorbent. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences 2009, 877 (11-12), 1200-1204.

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