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研究领域

1、稀土配合物发光探针的设计、合成及其在生物检测中的应用 2、钌配合物磷光探针的设计、合成及其在成像测定中的应用 3、纳米尺度荧光探针的研制及其在生物标记中的应用

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Lin Zhang, Yanjiao Wang, Zhiqiang Ye*, Dayong Jin, Jingli Yuan*, New class of tetradentate ?-diketonate-europium complexes that can be covalently bound to proteins for time-gated fluorometric application, Bioconjugate Chem., 2012, 23 (6), 1244-1251. Lu Tian, Zhichao Dai, Lin Zhang, Ruoyu Zhang, Zhiqiang Ye*, Jing Wu, Dayong Jin, Jingli Yuan*, Preparation and time-gated luminescence bioimaging applications of long-wavelength-excited silica-encapsulated europium nanoparticles, Nanoscale, 2012, 4 (11), 3551-3557. Run Zhang, Zhiqiang Ye,* Yuejiao Yin, Guilan Wang, Dayong Jin, Jingli Yuan,* James A. Piper, “Developing red-emissive ruthenium(II) complex-based luminescent probes for cellular imaging”, Bioconjugate Chemistry, 2012, 23(4), 725-733. Mingjing Liu, Zhiqiang Ye,* Guilan Wang and Jingli Yuan,* “Synthesis and time-gated fluorometric application of a europium(III) complex with a borono-substituted terpyridine polyacid ligand”, Talanta, 2012, 91, 116-121. Yunna Xiao, Zhiqiang Ye,* Guilan Wang and Jingli Yuan,* “A Ratiometric Luminescence Probe for Highly Reactive Oxygen Species Based on Lanthanide Complexes” Inorg. Chem., 2012, 51(5),2940-2946. Guanfeng Cui, Zhiqiang Ye*, Jinxue Chen, Guilan Wang, Jingli Yuan,* “Design and synthesis of a terbium(III) complex-based luminescence probe for time-gated luminescence detection of mercury(II) ions” J. Fluoresc., 2012, 22, 261-267. Xiangyou Liu, Zhiqiang Ye, Wei Wei, Yuguang Du, Jingli Yuan, Ding Ma, “Artificial luminescent protein as a bioprobe for time-gated luminescence bioimaging”, Chem. Commun., 2011, 47,8139-8141. Yonggang Chen, Weihua Guo, Zhiqiang Ye,* Guilan Wang and Jingli Yuan,* “A europium(III) chelate as an efficient time-gated luminescent probe for nitric oxide”, Chem. Commun., 2011, 47, 6266–6268. Zhiqiang Ye,* Jinxue Chen, Guilan Wang, Jingli Yuan,* “Development of a Terbium Complex-Based Luminescent Probe for Imaging Endogenous Hydrogen Peroxide Generation in Plant Tissues”, Anal. Chem. 2011, 83, 4163–4169. Run Zhang, Xiaojing Yu, Yuejiao Yin, Zhiqiang Ye,* Guilan Wang, Jingli Yuan,* ”Development of a heterobimetallic Ru(II)-Cu(II) complex for highly selective and sensitive luminescence sensing of sulfide anions”, Analytica Chimica Acta, 2011, 691, 83–88. Guanfeng Cui, Zhiqiang Ye*, Run Zhang, Guilan Wang, Jingli Yuan,* “Development of a novel terbium(III) chelate-based luminescent probe for highly sensitive time-resolved luminescence detection of hydroxyl radical”. Talanta, 2011, 84, 971–976. Wenzhu Zhang, Dan Zhao, Run Zhang, Zhiqiang Ye, Guilan Wang, Jingli Yuan, Mei Yang, “A ruthenium(II) complex based turn-on electrochemiluminescence probe for the detection of nitric oxide”, Analyst, 2011,136, 1867-1872. Burki Rajendar, Arivazhagan Rajendran, Zhiqiang Ye, Eriko Kanai, Yusuke Sato, Seiichi Nishizawa, Marek Sikorski and Norio Teramae. “Effect of substituents of alloxazine derivatives on the selectivity and affinity for adenine in AP-site-containing DNA duplexes”. Org. Biomol. Chem., 2010, 8(21), 4949-4959. Haitao Dong, Yan Liu, Dandan Wang, Wenzhu Zhang, Zhiqiang Ye*, Guilan Wang, Jingli Yuan*, “Preparation of europium-quantum dots and europium-fluorescein composite nanoparticles available for ratiometric luminescent detection of metal ions”, Nanotechnology, 2010, 21, 395504-395511. Zhiqiang Ye*, Guilan Wang, Jinxue Chen, Xiaoyan Fu, Wenzhu Zhang, Jingli Yuan*, “Development of a novel terbium chelate-based luminescent chemosensor for time-resolved luminescence detection of intracellular Zn2+ ions”, Biosens. Bioelectron., 2010, 26, 1043-1048. Cuihong Song, Zhiqiang Ye, Guilan Wang, Jingli Yuan*, Yafeng Guan*, “Core-shell nanoarchitectures: A strategy to improve the efficiency of luminescence resonance energy transfer”, ACS Nano, 2010, 4, 5389-5397. Run Zhang, Xiaojing Yu, Zhiqiang Ye*, Guilan Wang, Wenzhu Zhang, Jingli Yuan*, “Turn-on luminescent probe for cysteine/homocysteine based on a ruthenium(II) complex”, Inorg. Chem., 2010, 49 (17), 7898-7903. Run Zhang, Zhiqiang Ye*, Guilan Wang, Wenzhu Zhang, Jingli Yuan*, “Development of a ruthenium(II) complex-based luminescent probe for imaging nitric oxide production in living cells”, Chem. - Eur. J., 2010, 16 (23), 6884-6891. Cuihong Song, Zhiqiang Ye, Guilan Wang, Jingli Yuan*, Yafeng Guan*, “A lanthanide complex-based ratiometric luminescent probe specific for peroxynitrite”, Chem. - Eur. J., 2010, 16 (22), 6464-6472. Yan Liu, Haitao Dong, Wenzhu Zhang, Zhiqiang Ye,* Guilan Wang, Jingli Yuan*, “Preparation of a novel colorimetric luminescence sensor strip for the detection of indole-3-acetic acid”, Biosens. Bioelectron., 2010, 25 (10), 2375-2378. Lina Jiang, Jing Wu, Guilan Wang, Zhiqiang Ye*, Wenzhu Zhang, Dayong Jin, Jingli Yuan*, James Piper, “Development of a visible-light-sensitized europium complex for time-resolved fluorometric application”, Anal. Chem., 2010, 82 (6), 2529-2535. Hongfei Jiang, Guilan Wang, Wenzhu Zhang, Xiaoyu Liu, Zhiqiang Ye*, Dayong Jin, Jingli Yuan*, Zhiguang Liu, “Preparation and time-resolved luminescence bioassay application of multicolor luminescent lanthanide nanoparticles”, J. Fluoresc., 2010, 20 (1), 321-328. Haitao Dong, Yan Liu, Zhiqiang Ye*, Wenzhu Zhang, Guilan Wang, Zhiguang Liu, Jingli Yuan*, “Luminescent nanoparticles of silica-encapsulated cadmium-tellurium (CdTe) quantum dots with a core-shell structure: Preparation and characterization”, Helv. Chim. Acta, 2009, 92 (11), 2249-2256. Cuihong Song, Zhiqiang Ye, Guilan Wang, Dayong Jin, Jingli Yuan*, Yafeng Guan*, James Piper, “Preparation and time-gated luminescence bioimaging application of ruthenium complex covalently bound silica nanoparticles”, Talanta, 2009, 79 (1), 103-108. Weihua Guo, Zhiqiang Ye, Guilan Wang, Xiaoming Zhao, Jingli Yuan*, Yuguang Du*, “Measurement of oligochitosan-tobacco cell interaction by fluorometric method using europium complexes as fluorescence probes”, Talanta, 2009, 78 (3), 977-982. Jing Wu, Zhiqiang Ye, Guilan Wang, Dayong Jin, Jingli Yuan*, Yafeng Guan*, James Piper, “Visible-light-sensitized highly luminescent europium nanoparticles: preparation and application for time-gated luminescence bioimaging”, J. Mater. Chem., 2009, 19 (9), 1258-1264. Zhiqiang Ye, Burki Rajendar, Dai Qing, Seiichi Nishizawa, Norio Teramae, 6,7-Dimethyllumazine as a potential ligand for selective recognition of adenine opposite an abasic site in DNA duplexes, Chem. Commun., 2008, (48), 6588-6590.

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