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研究领域

生物多糖、蛋白质等生物大分子结构鉴定的色谱、质谱方法开发。 生物样本中多糖的提取、结构鉴定及功能研究。

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X. Sun, L. Li, K. H. Overdier, L. A. Ammons, I. S. Douglas, C. C. Burlew, F. Zhang, E. P. Schmidt, L. Chi, R. J. Linhardt, Analysis of total human urinary glycosaminoglycan disaccharides by liquid chromatography−tandem mass spectrometry, Analytical Chemistry (IF 6.320, 一区), 2015, 87, 6220-6227. X. Sun, L. Lin, X. Liu, F. Zhang, L. Chi, Q. Xia, R. J. Linhardt, Capillary Electrophoresis-Mass Spectrometry for the Analysis of Heparin Oligosaccharides and Low Molecular Weight Heparin, Analytical Chemistry (IF 6.320, 一区), 2016, 88, 1937-1943. X. Sun, A. Sheng, X. Liu, F. Shi, L. Jin, S. Xie, F. Zhang, R. J. Linhardt, L. Chi, Comprehensive identification and quantitation of basic building blocks for low molecular weight heparin, Analytical Chemistry (IF 6.320, 一区), 2016, 88, 7738-7744. X. Sun, Z. Guo, M. Yu, C. Lin, A. Sheng, Z. Wang, R. J. Linhardt, L. Chi, Hydrophilic interaction chromatography-multiple reaction monitoring mass spectrometry method for basic building block analysis of low molecular weight heparins prepared through nitrous acid depolymerization, Journal of Chromatography A (IF 3.981, 二区), 2016, 1479, 121-128. F. Li, X. Sun, W. He, C. Cai, A. Onishi, F. Zhang, R. J. Linhardt, Keratan sulfate glycosaminoglycan from chicken egg white, Glycobiology (IF 3.112, 二区), 2016, 26, 7, 693-700. Z. Liu, X. Sun, C. Cai, W. He, F. Zhang, R. J. Linhardt. Characteristics of glycosaminoglycans in chicken eggshells and the influence of disaccharide composition on eggshell properties, Poultry Science (IF 1.908, 三区), 2016, 0, 1-10. E. P. Schmidt, K. H. Overdier, X. Sun, L. Lin, X. Liu, Y. Yang, L. A. Ammons, T. D. Hiller, M. A. Suflita, Y. Yu, Y. Chen, F. Zhang, C. C. Burlew, C. L. Edelstein, I. S. Douglas, R. J. Linhardt, Urinary glycosaminoglycans predict outcomes in septic shock and ARDS, American Journal of Respiratory and Critical Care Medicine (IF 13.118, 一区), 2016, 194, 4, 439-449. E. Ucakturk, O. Akman, X. Sun, D. E. Baydar, A. Dolgun, F. Zhang, R. J. Linhardt, Changes in composition and sulfation patterns of glycosaminoglycans in renal cell carcinoma, Glycoconjugate Journal (IF 2.186, 三区), 2016, 33:103–112. Z. Wang, D. Li, X. Sun, X. Bai, L. Jin, L. Chi, Liquid chromatography-diode array detection-mass spectrometry for compositional analysis of low molecular weight heparins, Analytical Biochemistry (IF 2.334, 三区), 2014, 451, 35-41. K. St.Ange, A. Onishi, L. Fu, X. Sun, L. Lin, D. Mori, F. Zhang, J. S. Dordick, J. Fareed, D. Hoppensteadt, Walter Jeske, R. J. Linhardt, Analysis of heparins derived from bovine tissues and comparison to porcine intestinal heparins, Clinical and Applied Thrombosis and Hemostasis (IF 1.973, 四区), 2016, 22, 6, 520-527. W. He, Y. Zhu, A. Shirke, X. Sun, J. Liu, R. A. Gross, M. A. G. Koffas, R. J. Linhardt, M. Li, Expression of chondroitin-4-O-sulfotransferase in Escherichia coli and Pichia pastoris, Applied Microbiology and Biotechnology (IF 3.420, 二区), 2017), 1, 6919-6928. H. Wang, W. He, P. Jiang, Y. Yu, L. Lin, X. Sun, M. Koffas, F. Zhang, Robert J. Linhardt, Construction and functional characterization of truncated versions of recombinant keratanase II from Bacillus circulans, Glycoconjugate Journal (IF 2.186, 三区), 2017, 34, 643-649.

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