胡卫成 - 扬州大学 -

个人简介

胡卫成，男，扬州大学教授，担任Journal of Ginseng Research Associate Editor、Frontiers in Nutrition Associate Editor、Frontiers in Immunology Associate Editor、Frontiers in Pharmacology Associate Editor、eCAM Academic Editor、Journal of Immunology Research Academic Editor。主持国家自然科学基金、国家科技支撑子课题、国家星火计划、江苏省基金等省部级以上项目7项。课题组围绕药用植物的活性成分筛选、结构-效应关系研究以及关键靶蛋白的作用机制作为研究重点，取得了一系列研究成果。在Carbohydrate Polymers、Journal of Natural Product、Journal of Ginseng Research、Pytochemistry等期刊发表论文多篇；获国家发明专利7项（5项排名第一），参与制定国家标准2项。2020年获中国商业联合会科学技术一等奖（排名第一）。

研究领域

课题组围绕药用植物的活性成分筛选、结构-效应关系研究以及关键靶蛋白的作用机制作为研究重点，取得了一系列研究成果。

近期论文

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WeichengHu#,Xinfeng Wang#,Lei Wu#,Ting Shen, Lilian Ji, Xihong Zhao, Chuan-Ling Si*, Yunyao Jiang, andGongcheng Wang*. Apigenin-7-O-β-D-glucuronide inhibits LPS-inducedinflammation through the inactivation of AP-1 and MAPK singnalingpathways in RAW 264.7 macrophages and protects mice againstendotoxin shock. Food Function, Accept. WeichengHu#,Gongcheng Wang#,Pengxia Li#,Yuning Wang, Chuan-Ling Si*, Jing He, Wei Long, Yujia Bai, ZuoshanFeng, and Xinfeng Wang*. Neuroprotective effects of macranthoin Gfrom Eucommia ulmoides againsthydrogen peroxide-induced apoptosis in PC12 cells via inhibitingNF-κB activation. Chemico Biological Interaction, 2014, 224:108-116. Chuan-LingSi#*,Ting Shen#,Yun-Yao Jiang, Lei Wu, Guo-Jing Yu, Xiao-Dan Ren, Guang-Hui Xu, andWeicheng Hu*.Antioxidant properties and neuroprotective effects of isocampneosideII on hydrogen peroxide-induced oxidative injury in PC12 cells. Foodand Chemical Toxicology, 2013, 59: 145-152. WeichengHu#,Seok Ki Lee#,Mee Jung Jung, Seong-Il Heo, Jang Hyun Hur, and Myeong-Hyeon Wang*.Induction of cell cycle arrest and apoptosis by the ethyl acetatefraction of Kalopanax pcitusleaves in human colon cancer cells. Bioresource Technology, 2010,101: 9366-9371. WeichengHu#,Chaoqing Huang#,and Myeong-Hyeon Wang*.Chemical composition, nutritional value, and antioxidantconstituents of Kalopanax pictusleaves. Food Chemistry, 2012,131(2): 449-455. WeichengHu,LinglingYu, and Myeong-Hyeon Wang*.Antioxidant and antiproliferative properties of water extract fromMahonia bealei(Fort.) Carr. leaves. Food and Chemical Toxicology, 2011, 49(4):799-806. WeichengHu#,Woong Han#,Chaoqing Huang, and Myeong-Hyeon Wang*.Protective effect of methanolic extract from Duchesneaindica against oxidative stress invitro and in vivo.Environmental Toxicology and Pharmacology, 2011, 31(1): 42-50. Ling-LingYu, Weicheng Hu,Gang Ding, Rong-Tao Li, Jian-He Wei, Zhong-Mei Zou*,and Myeong-Hyeon Wang*.Gusanlungionosides A-D, potential tyrosinase inhibitors fromArcangelisia gusanlung.Journal of Natural Products, 2011, 74(5): 1009-1014. WeichengHu#,Ting Shen#, andMyeong-Hyeon Wang*.Cell cycle arrest andapoptosis by methyl3,5-dicaffeoyl quinatein human colon cancercells: Involvement of the PI3K/Akt and MAPkinase pathways. Chemico Biological Interaction, 2011, 194(1):48-57. WeichengHu andMyeong-Hyeon Wang*.Antioxidative activity andanti-inflammatory effects of diarylheptanoids isolated from Alnushirsute. Journal of Wood Science, 2011,57(4): 323-330. WeichengHu andMyeong-Hyeon Wang*.Diarylheotanoid from Alnushirsuta improvesglucose metabolism via insulin signal transduction in humanhepatocarcinoma (HepG2) cells. Biotechnology and BioprocessEngineering, 2011, 16(1): 120-126. WeichengHu#,Jin-Hee Yeo#,Yunyao Jiang, Seong-Il Heo, and Myeong-Hyeon Wang*.Antidiabetic effect of herb formulacomposed of Alnus hirsuta,Rosa davurica,Acanthopanax senticosusand Panax schinsengin streptozotocin-induced diabetic rats.Nutrition Research and Practice, 2013, 7(2): 103-108. Chuan-LingSi#*,Lei Wu#,Ting Shen#,Xiao-Feng Huang, Zhen-Guo Du, Xiao-Dan Ren, Xue-Gang Luo, andWei-Cheng Hu*.Recovery of low molecular weightgalloyltannins from agricultural residue of Juglanssigillata Dode seed husks and theirtyrosinase inhibitory effect. Bioresource, 2014, 9 (2): 2226-2236. WeiLong, Jian Xiang, Hongying Wu,WeichengHu, Xiaodong Zhang, Jin Jin, Xin He, XiuShen, Zewei Zhou, Saijun Fan*.QSAR modeling of iNOS inhibitors based on a novel regression method:Multi-stage adaptive regression. Chemometrics and IntelligentLaboratory Systems, 2013, 128: 83-88. Chuan-LingSi*, Guo-Jing Yu, Zhen-Guo Du, Xiao-Feng Huang, Su Fan, Hai-Shun Du,Wei-Cheng Hu*.A new cis-p-coumaroyl flavonol glycoside from the inner barks ofSophora japonica L. Holzforschung, DOI 10.1515/hf-2014-0342