聂作明 - 浙江理工大学 - 生命科学与医药学院

个人简介

1. 1997.9-2001.7 江南大学本科生 2. 2001.9-2004.7 江南大学硕士研究生 3. 2009.9-2015.11 浙江理工大学博士研究生 4. 2004.7-2010.9 浙江理工大学实习研究员，助理研究员 5. 2010.10-至今浙江理工大学副研究员，学科主任

研究领域

1. miRNA及其它新型非编码RNA的鉴定与功能研究 2. 家蚕生物反应器制备人用和兽用疫苗研究 3. 抗菌肽的规模化制备

近期论文

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1. Yong Zhou, Chengcheng Wu, Qing Sheng, Caiying Jiang, Qin Chen, Zhengbing Lv, Juming Yao, Zuoming Nie. The lysine acetylation stabilized the SP2 protein in the silkworm Bombyx mori. Journal of Insect Physiology, 2016 (online, 10.1016/j.jinsphys.2016.06.008) (通讯作者) 2. Wu C, Wang C, Li D, Liu Y, Sheng Q, Lv Z, Yu W, Nie Z. BmHSP20.8 is Localized in the Mitochondria and has a Molecular Chaperone Function In Vitro. J Insect Sci, 2015, 15. pii: 99. (通讯作者) 3. Nie Z, Zhu H, Zhou Y, Wu C, Liu Y, Sheng Q, Lv Z, Zhang W, Yu W, Jiang C, Xie L, Zhang Y, Yao J. Comprehensive profiling of lysine acetylation suggests the widespread function is regulated by protein acetylation in the silkworm, Bombyx mori. Proteomics, 2015, 15(18):3253-66. 4. Min Liu, Chan Wang, Dan Li, Yue Liu, Qing Sheng, Zhengbing Lv, Wei Yu, Dan Wang, Yaozhou Zhang, Zuoming Nie. Cloning and Expression Characteristics of the Notch-Associated Gene BmE(spl)mgama from Silkworm, Bombyx mori. Appl Biochem Biotechnol, 2014, 173(8):2065-75. (通讯作者) 5. Nie Z, Zhou F, Li D, Lv Z, Chen J, Liu Y, Shu J, Sheng Q, Yu W, Zhang W, Jiang C, Yao Y, Yao J, Jin Y, Zhang Y. RIP-seq of BmAgo2-associated small RNAs reveal various types of small non-coding RNAs in the silkworm, Bombyx mori. BMC Genomics, 2013, 14:661 6. Zhou F, Gao Z, Lv Z, Chen J, Hong Y, Yu W, Wang D, Jiang C, Wu X, Zhang Y, Nie Z. Construction of the ie1-Bacmid Expression System and Its Use to Express EGFP and BmAGO2 in BmN Cells. Appl Biochem Biotechnol, 2013, 169(8):2237-47. (通讯作者) 7. Yang L, Lu X, Liu Y, Lv Z, Chen J, Yu W, Zhang Y, Nie Z. Expression analysis of miRNAs in BmN cells. Gene, 2012, 505(2):240-245(通讯作者) 8. Nie Z, Lv Z, Qian J, Chen J, Li S, Sheng Q, Wang D, Shen H, Yu W, Wu X, Zhang Y. Molecular cloning and expression characterization of translationally controlled tumor protein in silkworm pupae. Mol Biol Rep, 2010, 37(6):2621-2628 9. Zuoming Nie, Ruobing Zhou, Jian Chen, DanWang, Zhengbing Lv, Pingan He, Xuedong Wang, Hongdan Shen, Xiangfu Wu, Yaozhou Zhang. Subcellular localization and RNA interference of an RNA methyltransferase gene from silkworm, Bombyx mori. Comparative and functional genomics, 2008:571023. 10. Zuoming Nie, Jiangtao Xu, Jian Chen , Zhengbing Lv, Dan Wang, Xuedong Wang, Xiangfu Wu, Yaozhou Zhang. Expression Analysis and Characteristics of Profilin Gene from Silkworm, Bombyx mori. Applied Biochemistry and Biotechnology, 2009,158 (1):59-71. 11. Ping-an He*, Zuoming Nie*, Jianqing Chen, Jian Chen, Zhengbing Lv, Qing Sheng, Songping Zhou, Xiaolian Gao, Lingyin Kong, Xiangfu Wu, Yongfeng Jin, Yaozhou Zhang. Identification and characteristics of microRNAs from Bombyx mori. BMC:Genomics, 2008, 9:248. (并列第一作者). 12. Nie ZM, Zhang ZF, Wang D, He PA, Jiang CY, Song L, Chen F, Xu J, Yang L, Yu LL, Chen J, Lv ZB, Lu JJ, Wu XF, Zhang YZ. Complete sequence and organization of Antheraea pernyi nucleopolyhedrovirus, a dr-rich baculovirus. BMC Genomics. 2007, 8:248. 13. Wenping Zhang, Changrong Zhang, Zhengbing Lv, Dailing Fang, Dan Wang, Zuoming Nie,Wei Yu, Hanglian Lan, Caiying Jiang, Yaozhou Zhang. Molecular Characterization, Tissue Distribution,Subcellular Localization and Actin-Sequestering Function of a Thymosin Protein from Silkworm. PLoS ONE 2012,7(2),e31040 14. Wenping Zhang, Hanglian Lan, Tao Wu, Caiying Jiang, Zhengbing Lv,Zuoming Nie, Xiangfu Wu ,Yaozhou Zhang. Expression Analysis and Characteristics of Hypothetical Protein BmLOC778500 from Silkworm, Bombyx mori African Journal of Biotechnology 2011,10(19) :3753-3761. 15. Chen J, Gai Q, Lv Z, Chen J, Nie Z, Wu X, Zhang Y. All-trans retinoic acid affects subcellular localization of a novel BmNIF3l protein: functional deduce and tissue distribution of NIF3l gene from silkworm (Bombyx mori). Arch Insect Biochem Physiol. 2010, 74(4):217-31. 16. Hanglian Lan, Zuoming Nie, Yue Liu, Zhengbing Lv, Yingshuo Liu, Yanping Quan, Jianqing Chen, Qingliang Zhen, Qin Chen, Dan Wang, Qing Sheng, Wei Yu, Jian Chen, Xiangfu Wu, and Yaozhou Zhang. In vivo Bioassay of Recombinant human growth hormone synthesized in B. mori pupae. Journal of Biomedicine and Biotechnology, 2010:306462. 17. Sheng Q, Xia J, Nie Z, Zhang Y. Cloning, Expression, and Cell Localization of a Novel Small Heat Shock Protein Gene: BmHSP25.4.Appl Biochem Biotechnol, 2010 Ja,n 14. 2010, 162(5):1297-305. 18. Zeng F, Xie H, Nie Z, Chen J, Lv Z, Chen J, Wang D, Liu L, Yu W, Sheng Q, Wu X, Zhang Y. Characterization of the Gene BmEm4, a Homologue of Drosophila E(spl)m4, from the Silkworm, Bombyx mori. Comp Funct Genomics, 2009:947490. 19. Shen Y, Zhang T, Chen J, Lv Z, Chen J, Wang D, Nie Z, He P, Wang J, Zheng Q, Sheng Q, Wu X, Zhang Y. Molecular Characterization and Tissue Localization of an F-Box Only Protein from Silkworm, Bombyx mori. Comp Funct Genomics. 2009:416040. 20. Zhang Y, Xia Q, Xu J, Chen J, Nie Z, Wang D, Zhang W, Chen J, Zheng Q, Chen Q, Kong L, Ren X, Wang J, Lv Z, Yu W, Jiang C, Liu L, Sheng Q, Jin Y, Wu X. Aligning the proteome and genome of the silkworm, Bombyx mori. Funct Integr Genomics, 2009, 9(4):447-54.