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个人简介

1. 1984.9-1988.6 南京大学 植物学专业 理学学士 2. 1998.9-2002.6 浙江省医学科学院 病原生物学专业 医学硕士 3. 2004.2-2009.12 浙江大学 生物化工专业(生物制药方向)工学博士 4. 1988.7-2004.3 浙江省医学科学院保健食品研究所 助理研究员/副研究员 5. 2004.3至今 浙江理工大学 教授 6. 2010.5-2011.5 美国加州大学旧金山分校(UCSF)医学院癌症中心 访问学者 7. 2010.4-2012.4 清华大学 博士后

研究领域

1. 家蚕功能基因组学与酶学应用基础方面的研究; 2. 肺癌、胃癌等癌细胞信号通路中成员基因与癌症发生之间的关系和作用机制

近期论文

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1. M L Mo, M R. Li, Z. Chen, X W. Liu, Q Sheng*, H.M. Zhou*, Inhibition of the Wnt palmitoyltransferase porcupine suppresses cell growth and downregulates the Wnt/β-catenin pathway in gastric cancer, Oncol Lett. 2013, 5(5):1719-1723. 2. Ma H Y, Zhang F, LI J, Mo M L, Chen Z, Liu L L, Zhou H M, Sheng Q*. HSulf-1 suppresses cell growth and down-regulates Hedgehog signaling in human gastric cancer cells. Oncol Lett, 2011,2: 1291-1295. 3. Sheng Q, Xia J Y, Nie Z M, Zhang Y Z. Cloning, expression, and cell localization of a novel small heat shock protein gene: BmHSP25.4. Appl Biochem Biotechnol, 2010DOI 10.1007/s12010-009-8890-7. 4. Sheng Q, Zou H C, Lü Z R, Zou F, Park Y D, Yan Y B, Yao S J. Effects of acrylamide on the activity and structure of human brain creatine kinase, Int J Mol Sci, 2009, 10: 4210-4222. 5. Sheng Q, Lü Z R, Mu H, Zou H C, Zou F, Yao S J. The effect of Ag+ on arginine kinase: inhibition kinetics. J Biomol Struct Dyn, 2009, 27: 59-64. 6. ML. Mo, Z. Chen, J. Li, HL. Li, Q Sheng, HY. Ma, FX. Zhang, YW. Hua, X. Zhang, DQ. Sun, ML. Xu, RG. Niu, J.Pu Xu, HJ. Zuo, M. Liu, HM. Zhou Use of serum circulating CCNB 2 in cancer surveillance. Int J Biol Markers, 2010; 25 ( 4 ): 236-242. 7. J Li, ML. Mo, Z. Chen, Z. Chen, Q Sheng, H. Mu, F. Zhang3, Y. Zhang, XY. Zhi,H. Li, B. He*, HM. Zhou*. Adenoviral Delivery of the EMX2 Gene Suppresses Growth in Human Gastric Cancer. 2012,7(9):e45970. 8. ZB. Lv, XF. Zhang, LL. Liu, J. Chen, ZM. Nie, Q Sheng,WP. Zhang, CY. Jiang, W. Yu, D. Wang, XF. Wu, SJ. Zhang. Characterization of a gene encoding prohibitin in silkworm, Bombyx mori. Gene .2012, 502(2):118-24. 9. Nie Z M, Xu J, Chen J, Lv Z B, Wang D, Sheng Q, Wu Y, Wang X, Wu X, Zhang Y. Expression analysis and characteristics of profilin gene from silkworm, Bombyx mori. Appl Biochem Biotechnol, 2009, 158: 59-71. 10. He P A, Nie Z M, Chen J Q, Chen J, Lv Z B, Sheng Q, Zhou S P, Gao X L, Kong L Y, Wu X F, Jin Y F, Zhang Y Z. Identification and characteristics of microRNAs from Bombyx mori. BMC Genomics, 2008, 9: 248.

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