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Zhang, K.; Li, H.; Cho, K.M. and Liao, J.C. (2010) Expanding metabolism for total biosynthesis of the nonnatural amino acid L-homoalanine. Proc Natl Acad Sci U S A. 107(14):6234-9. PMID: 20332210. Atsumi,S.; Higashide, W.; and Liao, J.C. (2009) Direct recycling of carbon dioxide to isobutyraldehyde using photosynthesis, Nat Biotechnol, 27, 1177-1180. PMID: 19915552 Zhang, K., Sawaya, M.R., Eisenberg, D.S. and J.C. Liao (2008) Expanding Metabolism for Biosynthesis of Nonnatural Alcohols, Proc. Natl. Acad. Sci. USA 105: 20653–20658 Dean, J.T.; Tran, L.; Beaven, S.; Tontonoz, P; Reue, K.; Dipple, K.D.; and Liao, J.C. (2009) Resistance to Diet-Induced Obesity in Mice with Synthetic Glyoxylate Shunt, Cell Metabolism, 9, 525–536. PMID: 19490907. (Selected for Faculty of 1000 Biology) Brynildsen, M.P.; and Liao, J.C. (2009) An integrated network approach identifies the isobutanol response network of Escherichia coli. Mol. Sys. Biol. 5:277. PMID: 19536200 Atsumi, S.; Li, Z. and Liao, J.C. (2009) Acetolactate Synthase from Bacillus subtilis Serves as a 2-Ketoisovalerate Decarboxylase for Isobutanol Biosynthesis in Escherichia coli, Appl. Env.Microbiol. 75: 6306–6311 PMID: 19684168 Atsumi, S.; T. Hanai and J.C. Liao (2008) Non-Fermentative Pathways for Synthesis of Branched-Chain Higher Alcohols as Biofuels, Nature, 451:86-89. Hanai, T., S. Atsumi, J. C. Liao (2007) Engineered synthetic pathway for isopropanol production in Escherichia coli. Appl. Env. Microbiol. 73:7814–7818 Atsumi, S., A. F. Cann, M. Connor, C.R. Shen, K. M. Smith, M.P. Brynildsen, K.J.Y. Chou, T. Hanai, and J. C. Liao (2008) Metabolic engineering of Escherichia coli for 1-butanol Production. Metabolic Eng. 10 (2008) 305–311 Farmer, W.R. and J.C. Liao, (2000) Improving Lycopene Production in Escherichia coli by Engineering Metabolic Control. Nature Biotechnol., 18, 533-537. Wong, W.W., T.Y. Tsai, J.C. Liao (2007) Single-cell zeroth-order protein degradation enhances the robustness of synthetic oscillator. Mol. Systems. Biol., 3:130. Wong ,WW and Liao, JC. (2006) The design of intracellular oscillators that interact with metabolism. Cell. Mol. Life Sci., 1215-1220 Fung, E., Wong, W.W., Suen, J.K., Bulter, T., Lee, S.G., and Liao, J.C. (2005) A synthetic gene-metabolic oscillator. Nature, 435, 118-122. Bulter, T, . Lee, S.-G., Wong, W.W., Fung, E., Connor, M.R. and Liao, J.C. (2004) Design of artificial cell-cell communication using gene and metabolic networks. Proc. Natl. Acad. Sci. USA, 101:2299-2304 [Commentary by Gerchman and Weiss, PNAS, 2004 101:2221-2222] Dean, J.T.; Rizk, M.L.; Tan, Y.; Dipple, K.M.; and Liao, J.C. (2010) Ensemble modeling of hepatic fatty acid metabolism with a synthetic glyoxylate shunt. Biophys J. 98:1385-95. PMID: 20409457. Rizk, M.L.; Liao, J.C. (2009) Ensemble modeling for aromatic production in Escherichia coli. PLoS One. 4(9):e6903.PMID: 19730732 Contador, C.A.; Rizk, M.L.; Asenjo, J.A.; and Liao, J.C. (2009) Ensemble modeling for strain development of L-lysine-producing Escherichia coli. Metab. Eng. 11:221–233. PMID: 19379820 Tran, L.M.; Rizk, M.L.; and J.C. Liao (2008) Ensemble Modeling of Metabolic Networks. Biophys J. 95:5606-17. Hyduke, D.R., Jarboe, L.R., Tran, L.M., Chou, K.J.Y., Liao, J.C. (2007) Integrated Network Analysis Identifies Nitric Oxide Response Networks and dihydroxyacid dehydratase as a Crucial Target in Escherichia coli. Proc. Natl. Acad. Sci. USA, 104, 8484-8489. [Highlighted in Chemical &, Engineering News, Aug. 20, 2007, Page 57]. Brynildsen, M.P., Wu, T.Y., Jang, S.S. and Liao, J.C. (2007) Biological Network Mapping and Source Signal Deduction. Bioinformatics, 23:1775-1782. Brynildsen, M.P., Tran, L. M. and Liao, J.C. (2006) A Gibbs Sampler for the Identification of Gene Expression and Network Connectivity Consistency. Bioinformatics, 22, 3040-3046. Kao, K.C, Tran, L.M., Liao, J.C.(2005) A global regulatory role of gluconeogenic genes in Escherichia coli revealed by transcriptome network analysisi. J. Biol. Chem., 280, 36079-36087. Galbraith, S.J., Tran, L.M. and Liao, J.C. (2006) Transcriptome Network Component Analysis with Limited Microarray Data. Bioinformatics, 22, 1886-1894. Sabatti, C, Rohlin, L, Lange, K, and Liao, J.C. (2005) Vocabulon: a dictionary model approach for reconstruction and localization of transcription factor binding sites. Bioinformatics, 21(7):922-31. Tran, L.M., M.P. Brynildsen, K. C. Kao, J. K. Suen and J. C. Liao (2005) gNCA: A framework for determining transcription factor activity based on transcriptome: Identifiability and numerical implementation. Metabolic Engineering., 7, 128-141 Kao, K.C., Yang, Y., Boscolo, R., Sabatti, C., Roychowdhury, V. and Liao, J.C. (2004) Transcriptome-based determination of multiple transcription regulator activities in Escherichia coli using network component analysis. Proc. Natl. Acad. Sci. USA, 101:641-646. Liao, J.C., Boscolo, R, Yang, Y.L., Tran,L.M., Sabatti, C., and Roychowdhury, V. (2003) Network component analysis: Reconstruction of regulatory signals in biological systems. Proc. Natl. Acad. Sci. USA, 100: 15522-15527. Sabatti, C. Rohlin, L, Oh, M.K., and Liao, J.C. (2002) Co-expression pattern from DNA microarray experiments as a tool for operon prediction. Nucl. Acids. Res., 30: 2886-2893 Tseng, G.C., M.-K.Oh, L Rohlin, J, C. Liao, and W.H. Wong (2001) Issues In cDNA Microarray Analysis: Quality Filtering Channel Normalization, Models of Variations and Assessment of Gene Effects Nucleic Acid Research, 29, 2549-2557.

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